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Pseudo script at Gebel el Silsila : an introduction to Ancient Egyptian quarry marks

The ancient Egyptian site of Gebel el Silsila is known for its many pharaonic stelai, funerary shrines and the famous rock-cut chapel of Pharaoh Horemheb, but this article leaves the Pharaohs’ chronicles and explores instead a complex and mysterious marking system that is preserved as engravings in the site’s extensive quarries that run on both sides of the Nile. Here we will investigate Graeco-Ro

USING AN OPTIMISED OSL SINGLE-ALIQUOT REGENERATIVE-DOSE PROTOCOL FOR LOW-DOSE RETROSPECTIVE DOSIMETRY ON HOUSEHOLD SALT.

The single-aliquot regenerative-dose (SAR) protocols used in retrospective dosimetry for optically stimulated luminescence measurements have been mainly developed for archaeological and geological dating of quartz and feldspar. The aim in this study is to find a read-out protocol that can generate the most reproducible signal for household salt (NaCl) at absorbed doses below 100 mGy. The relation

MICRODOSING FOR EARLY BIOKINETIC STUDIES IN HUMANS.

Microdosing is a new concept in drug development that-if implemented in the pharmaceutical industry-would mean that new drugs can be tested earlier in humans than done today. The human microdosing concept-or 'Phase 0'-may offer improved candidate selection, reduced failure rates in the drug development line and a reduction in the use of laboratory animals in early drug development, factors which w

Disturbed vibrotactile sense in finger pulps in patients with Type 1 diabetes-correlations with glycaemic level, clinical examination and electrophysiology.

Aims In a cohort of men and women with Type 1 diabetes, prospectively followed for > 20 years, vibrotactile sense in fingers was investigated and related to neurophysiological tests, glycaemic level and clinical score. Methods Out of 58 patients, diagnosed at the age of 15-25 years and recruited 1984-1985, 32 patients (13 women, median age 52 years, range 44-75 years; 19 men, median age 52 years,

Overview on health research ethics in Egypt and North Africa.

Developing countries, including Egypt and North African countries, need to improve their quality of research by enhancing international cooperation and exchanges of scientific information, as well as competing for obtaining international funds to support research activities. Research must comply with laws and other requirements for research that involves human subjects. The purpose of this article

Sensitizing capacity and cross-reactivity of phenyl glycidyl ether studied in the guinea-pig maximization test.

BACKGROUND: Simultaneous contact allergies to the reactive diluent phenyl glycidyl ether (PGE) and epoxy resins based on diglycidyl ether of bisphenol A (DGEBA) or epoxy resins of the bisphenol F-type have been reported. The latter epoxy resins contain three isomers of diglycidyl ether of bisphenol F (DGEBF). PGE, DGEBA, and DGEBF are chemically similar with respect to the reactive glycidyl group

Improving the survival of grafted dopaminergic neurons: a review over current approaches

Neural transplantation is developing into a therapeutic alternative in Parkinson's disease. A major limiting factor is that only 3-20% of grafted dopamine neurons survive the procedure. Recent advances regarding how and when the neurons die indicate that events preceding actual tissue implantation and during the first week thereafter are crucial, and that apoptosis plays a pivotal role. Triggers t

Tensile Strength of Surgical Knots Performed with the da Vinci Surgical Robot.

The objective of this study was to estimate the tensile strength of surgical knots made using the da Vinci robot. Four different types of flat square knots (strand-to-strand 4 throw, strand-to-strand 6 throw, loop-to-strand 4 throw, and loop-to-strand 6 throw) were made using the da Vinci-S system by 4 different surgeons, all experienced with the system. For the knots, we used braided polyglactin

Is contact allergy to disperse dyes and related substances associated with textile dermatitis?

Summary Background Disperse dyes (DDs) are the most common sensitizers among textile dyes, but there is little knowledge of the clinical relevance of positive patch test reactions. Objective To investigate if patient-reported textile-related skin problems can be explained by contact allergy to eight different DDs and/or to chemically related substances, by occupation or by atopic constitution, and

Pre-Emptive Treatment With Rituximab of Molecular Relapse After Autologous Stem Cell Transplantation in Mantle Cell Lymphoma.

PURPOSE: Minimal residual disease (MRD) is predictive of clinical progression in mantle-cell lymphoma (MCL). According to the Nordic MCL-2 protocol we prospectively analyzed the efficacy of pre-emptive treatment using rituximab to MCL patients in molecular relapse after autologous stem cell transplantation (ASCT). Patients and Materials: MCL patients enrolled in the study, who had polymerase chain