Aim: To describe the clinical course, morbidity and platelet recovery in an unselected Nordic cohort of children with chronic Immune Thrombocytopenic Purpura (ITP). Methods: Prospective 5-year follow-up of 96 children with ITP lasting more than 6 months, with reporting of hospital admissions, severity of bleeding episodes, and stabilization of platelet counts above 20, 50 and 150 x 10(9) /L. R

BACKGROUND: Mutations altering BLM function are associated with highly elevated cancer susceptibility (Bloom syndrome). Thus, genetic variants of BLM and proteins that form complexes with BLM, such as TOP3A and RMI1, might affect cancer risk as well. METHODS: In this study we have studied 26 tagged single nucleotide polymorphisms (tagSNPs) in RMI1, TOP3A, and BLM and their associations with cancer

The project “3D-Digging at Çatalhöyük” began in 2010 thanks to collaboration between Stanford University (Archaeological Center) and the University of California Merced with the scope to record, document (with different digital technologies) and visualize in virtual reality all the phases of archaeological excavation. Phase I (2010 excavation season) of the project was mainly oriented to test diff

50 years ago, on June 11, 1963 president John F Kennedy, in live television, gave his commemorated speech to the American people where he declared his demand for civil rights for all Americans. The film Guess who is coming to dinner (Stanley Kramer, 1967) was an attempt to raise this question again by bringing up the topic of interracial marriage. This essay aims at studying how this is done, by s

Addiction treatment often requires medical, psychosocial and social expertise - and benefits from collaboration. The pronounced role of social authorities in evaluation and treatment is unique to the addiction field. Unified responsibility for evaluation and treatment of addiction is under consideration. Treatment of psychiatric and physical co-morbidity benefits from a unified responsibility with

In myocardial ischemia-reperfusion (I/R) injury, complement activation, tissue plasminogen activator (t-PA) and extracellular adenosine triphosphate (ATP) release contribute to myocardial injury. ATP is degraded into adenosine by the enzyme apyrase, and adenosine possesses cardioprotective properties. ADC-1004 is an antagonist of the receptor to the activated complement factor C5a. Hypothermia has

The structure of interest is a thin, metallic coating of fcc copper, of thickness down to a few nanometers only, resting on a stiffer substrate. The elastic and plastic properties of the thin coating using nanoindentation under different geometrical features such as size of the indenter and coating thickness are determined. The force-displacement curve is monitored during indentation and the preci

In order to promote phase separation and properties of anion-exchange membranes (AEMs)we have prepared polysulfones with an exceptionally high local concentration of imidazolium groups. Statistical copolymers containing single dioxyphenylene rings directly functionalized with four cationic groups were synthesized by polycondensations of 4,4’-dichlorodiphenylsulfone, 4,4′-isopropylidenediphenol and

The mill in Lilla Harrie vas belonging to noble families in the medieval period. It was confiscated by the king in 1502 and sold to the archbishop in 1509. By the reformation in the 1530:ies it again came to be owned by the king. It belonged to the castle in Landskrona and in the royal archives it is possible to follow the developement of the mill in detail up to the swedish conquest in 1658. Then

A leaky lens antenna system for short pulse applications is designed, fabricated and characterized. The antenna has very good phase center stability over large bandwidths. The leaky lens antenna is connected to an in-house wavelet generator to transmit 100 ps pulses centered at 57.5 GHz. It is shown that the antenna preserves the reference pulse shape and has very low dispersion.

In the beginning of the 1990s, Sweden experienced an economic recession. The unemployment rate increased significantly and the proportion of young adults receiving social assistance rose dra-matically. In response, municipalities initiated local intervention programs aimed at reducing the number of young social assistance recipients. In 2005, this population had decreased. However, the organizatio