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Ultraviolet prepulse for enhanced x-ray emission and brightness from droplet-target laser plasmas

We show that an ultraviolet prepulse significantly enhances the water-window x-ray emission and brightness for a droplet-target laser plasma. By combining a 65 mJ, 120 ps, lambda = 532 nm main pulse with an up to 3 mJ prepulse, the emitted x-ray photon flux may be increased more than eight times. The resulting C VI lambda = 3.37 nm line emission is more than 3 x 10(12) photons/sr . pulse, correspo

Application of a watershed runoff model to north-east pond river, Newfoundland: To study water balance and hydrological characteristics owing to atmospheric change

The hydrological sensitivities to long-term climate change of a watershed in Eastern Canada were analysed using a deterministic watershed runoff model developed to simulate watershed acidification. This model was modified to study atmospheric change effects in the watershed. Water balance modelling techniques, modified for assessing climate effects, were developed and tested for a watershed using

Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis.

HAMLET is the first member of a new family of tumoricidal protein-lipid complexes that kill cancer cells broadly, while sparing healthy, differentiated cells. Many and diverse tumor cell types are sensitive to the lethal effect, suggesting that HAMLET identifies and activates conserved death pathways in cancer cells. Here, we investigated the molecular basis for the difference in sensitivity betwe

SHP-2 binds to Tyr763 and Tyr1009 in the PDGF beta-receptor and mediates PDGF-induced activation of the Ras/MAP kinase pathway and chemotaxis

Activation of the beta-receptor for platelet-derived growth factor (PDGF) by its ligand leads to autophosphorylation on a number of tyrosine residues. Here we show that Tyr763 in the kinase insert region is a novel autophosphorylation site, which after phosphorylation binds the protein tyrosine phosphatase SHP-2. SHP-2 has also previously been shown to bind to phosphorylated Tyr1009 in the PDGF be

Subarachnoid Hemorrhage Induces Enhanced Expression of Thromboxane A(2) Receptors in Rat Cerebral Arteries.

Cerebral ischemia remains the key cause of morbidity and mortality after subarachnoid hemorrhage (SAH) with a pathogenesis that is still poorly understood. The aim of the present study was to examine the involvement of thromboxane A(2) receptors (TP) in the patophysiology of cerebral ischemia after SAH in cerebral arteries. SAH was induced in rats by injecting 250 microl blood into the prechiasmat

Social capital, political trust and self-reported psychological health: A population-based study.

This study investigates the association between political trust (an aspect of institutional trust) in the Riksdag (the national parliament in Sweden) and self-reported psychological health, taking generalized (horizontal) trust in other people into account. The 2004 public health survey in Skåne in Southern Sweden is a cross-sectional postal questionnaire study that was answered by 27,757 responde

Transport Phenomena Coupled by Chemical Reactions in Methane Reforming Ducts

Mass, heat and momentum transport processes are strongly coupled with catalytic chemical reactions in a methane steam reforming duct. In this paper, a three-dimensional calculation method is developed to simulate and analyze reforming reactions of methane, and the effects on various transport processes in a steam reforming duct. The results show that the design and operating parameters grouped as

Cystatins - Extra- and Intracellular Cysteine Protease Inhibitors: High-level Secretion and Uptake of Cystatin C in Human Neuroblastoma Cells.

Cystatins are present in mammals, birds, fish, insects, plants, fungi and protozoa and constitute a large protein family, with most members sharing a cysteine protease inhibitory function. In humans 12 functional cystatins exist, forming three groups based on molecular organisation and distribution in the organism. The type 1 cystatins (A and B) are known as intracellular, type 2 cystatins (C, D,

Intra-individual variations and temporal trends in dioxin levels in human blood 1987-2002.

OBJECTIVES: In Sweden, an important source for exposure to persistent organochlorine pollutants, such as PCDD and PCDF, is through intake of fatty fish from the Baltic Sea off the Eastern coast of Sweden. The present study assesses temporal trends for human levels of PCDD/F between 1987 and 2002 among 26 men from Sweden. In addition, we investigate the impact of potential determinants (age, relati

Acupuncture reduces crying in infants with infantile colic: a randomised, controlled, blind clinical study.

OBJECTIVE: To investigate whether acupuncture reduces the duration and intensity of crying in infants with colic. Patients and methods 90 otherwise healthy infants, 2-8 weeks old, with infantile colic were randomised in this controlled blind study. 81 completed a structured programme consisting of six visits during 3 weeks to an acupuncture clinic in Sweden. Parents blinded to the allocation of th

Words that second language learners are likely to hear, read, and use

In the present study, we explore whether multiple data sources may be more effective than single sources at predicting the words that language learners are likely to know. Second language researchers have hypothesized that there is a relationship between word frequency and the likelihood that words will be encountered or used by second language learners, but it is not yet clear how this relationsh

Theory of high-order sum and difference frequency mixing in a strong bichromatic laser field

We generalize the recently formulated theory of high-order harmonic generation by low-frequency laser fields to the case of high-order sum and difference frequency mixing in a two-color field of noncommensurate frequencies in the optical-infrared regime. Our theoretical description includes both the single-atom response and propagation. We observe a different behavior of the sum and difference fre

Hypersensitivity and the working environment for allergy nurses in sweden.

Background. Allergy nurses are exposed to allergens and respiratory irritants, and there are no national guidelines addressing personnel safety when working with these agents. Objective. To investigate the prevalence of allergies, asthma, and hypersensitivity symptoms among allergy nurses and the use of protective equipment and measures when working with allergen concentrates and respiratory irrit

Low-Level Cadmium Exposure Is Associated with Decreased Bone Mineral Density and Increased Risk of Incident Fractures in Elderly Men: The MrOS Sweden Study.

One risk factor for osteoporosis which has attracted increasing attention in recent years is exposure to cadmium. The aim of this study was to examine the associations between low-level cadmium exposure, from diet and smoking, and BMD and incident fractures in elderly men. The study population consisted of 936 men from the Swedish cohort of the MrOS study, aged 70-81 years at inclusion (year 2002-

Further results on asymmetric authentication schemes

This paper derives some further results on unconditionally secure asymmetric authentication schemes. It starts by giving a general framework for constructing A2-codes, identifying many known constructions as special cases. Then a full treatment of A3-codes (A2-codes protecting against arbiter's attacks) is given, including bounds on the parameters and optimal constructions. With these models as a

Phagocytosis of apoptotic cells by macrophages in anti-neutrophil cytoplasmic antibody-associated systemic vasculitis.

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of autoimmune diseases, including granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). It is not known why ANCA develop, but it has been shown that they participate in pathogenesis by activating polymorphonuclear neutrophils (PMNs). In this study we hypothesize that dysregulation of phagocytosi

Alternative food systems and the citizen-consumer

Ethically informed and committed consumers are crucial to the functioning of many alternative food systems. These consumers are poorly understood, though, and their common description as informed and democratically minded finds little resemblance to the real world. Few individuals fit the ideal of the concept of the so-called citizen-consumer. This commentary therefore argues that both researchers