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Hand function after nerve repair.

Treatment of injuries to major nerve trunks in the hand and upper extremity remains a major and challenging reconstructive problem. Such injuries may cause long-lasting disabilities in terms of lost fine sensory and motor functions. Nowadays there is no surgical repair technique that can ensure recovery of tactile discrimination in the hand of an adult patient following nerve repair while very you

Detecting shifts of transmission areas in avian blood parasites - a phylogenetic approach

We investigated the degree of geographical shifts of transmission areas of vector-borne avian blood parasites (Plasmodium, Haemoproteus and Leucocytozoon) over ecological and evolutionary timescales. Of 259 different parasite lineages obtained from 5886 screened birds sampled in Europe and Africa, only two lineages were confirmed to have current transmission in resident bird species in both geogra

Genotyping of hepatitis C virus isolates by a modified polymerase chain reaction assay using type specific primers: epidemiological applications

A polymerase chain reaction (PCR)-based assay using primers against the hepatitis C core gene has been described [Okamoto et al. (1992a): Journal of General Virology 73:673-679]. Within the two major HCV genotypes 1 and 2, the Okamoto system identifies two subtypes each (1a, 1b and 2a, 2b, respectively). Typing is achieved by a primary PCR with consensus primers followed by a nested PCR with type

Effects of malaria double infection in birds: one plus one is not two.

Avian malaria parasites are supposed to exert negative effects on host fitness because these intracellular parasites affect host metabolism. Recent advances in molecular genotyping and microscopy have revealed that coinfections with multiple parasites are frequent in bird-malaria parasite systems. However, studies of the fitness consequences of such double infections are scarce and inconclusive. W

Gate-defined quantum-dot devices realized in InGaAs/InP by incorporating a HfO2 layer as gate dielectric

Gate-defined quantum dots in an InGaAs/InP heterostructure are realized by incorporating a high-kappa HfO2 material as a gate dielectric using atomic layer deposition. The fabricated quantum-dot devices show Coulomb blockade effect at low temperature. The Coulomb blockade current peaks are found to shift in pairs with the magnetic field applied perpendicular to the quantum-dot plane, due to the fi

Restorative neurology in movement disorders

Cell replacement for restoration of neurological functions in patients with movement disorders has been investigated for more than 15 years. Initial attempts used autologous adrenal medulla grafts implanted into the denervated striatum of patients with Parkinson's disease (PD). This approach was soon abandoned in favor of intrastriatal implantation of human embryonic mesencephalic tissue, rich in

Democratization and Women's Empowerment: The Effects of Electoral Systems, Participation and Repetition in Africa.

This article investigates three hypotheses suggested in the literature on women's political empowerment, operationalized here as increased legislative representation. These hypotheses are that (1) electoral systems manipulate women's political empowerment; (2) increased popular participation empowers women in particular; and (3) accumulated experience gained over several electoral cycles facilitat

The potential of polymeric cryogels in bioseparation

This is a review discussing the production and properties of cryogels (from the Greek κριoσ (kryos) meaning frost or ice), immobilization of ligands in cryogels and the application of affinity cryogels in bioseparation. Cryotropic gel formation proceeds in a non-frozen liquid microphase existing in the macroscopically frozen sample. Due to the cryoconcentration of gel precursors in the non-frozen

Two major classes in the M protein family in group A streptococci

The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, wh

Risk of collapse in the eastern Baltic cod fishery

The eastern Baltic cod fishery, as many fisheries worldwide, is experiencing a major crisis. The combination of current environmental conditions, fishing mortality rates, and stock size indicates that this fishery is not sustainable. In order to rebuild the population and sustain the fishery in the future, it is essential to define a biologically appropriate exploitation level. In this paper, we t

Photochemical reactivity of aquatic macrophyte leachates: abiotic transformations and bacterial response

We evaluated the influence of UV radiation exposure time on abiotic transformations of leachates from 2 aquatic macrophytes: Phragmites australis and Hydrocaris morsus-ranae. In addition, we studied the influence of phototransformations of DOM on bacterial growth. Sterile filtered leachates were exposed to UV radiation for 5, 10, 24, 48, 72 and 120 h or kept in the dark. Dissolved inorganic carbon

ACTH reduces the rise in ApoB-48 levels after fat intake.

It has been repeatedly demonstrated that ACTH administration lowers plasma lipid concentrations in man. The present study was designed to test the hypothesis, based on observations of decreased apolipoprotein B (ApoB) synthesis and secretion in vitro, that ACTH administration inhibits the postprandial output of ApoB in man. Therefore, we studied the response to a fat-rich meal supplemented with Vi

Sensed presence and mystical experiences are predicted by suggestibility, not by the application of transcranial weak complex magnetic fields

Transcranial magnetic stimulation (TMS) with weak (micro Tesla) complex waveform fields have been claimed to evoke the sensed presence of a sentient being in up to 80% in the general population. These findings have had a questionable neurophysiological foundation as the fields are approximately six orders of magnitude weaker than ordinary TMS fields. Also, no independent replication has been repor

Effects of litter addition and warming on soil carbon, nutrient pools and microbial communities in a subarctic heath ecosystem

Climatic warming leads to the expansion of deciduous shrubs and trees in the Arctic. This leads to higher leaf litter inputs, which together with warming may alter the rate of carbon and nutrient cycling in the arctic ecosystems. We assessed effects of factorial warming and additional litter on the soil ecosystem of a subarctic heath in a 7-year-long field experiment. Fine root biomass, dissolved

Oxidized LDL antibodies in treatment and risk assessment of atherosclerosis and associated cardiovascular disease.

Immune responses against oxidized forms of LDL play a critical role in activation and regulation of the inflammatory process that characterizes all stages of atherosclerosis. In humans oxidized LDL is targeted by both IgM and IgG autoantibodies. Immunization of hypercholesterolemic animals with oxidized LDL has been shown to inhibit atherosclerosis demonstrating that at least some of these immune

The instability of planetary systems in binaries: how the Kozai mechanism leads to strong planet-planet interactions

In this Letter we consider the evolution of a planetary system around a star inside a wide binary. We simulate numerically the evolution of the planetary orbits for both coplanar and highly inclined systems. We find that the Kozai mechanism operates in the latter case. This produces a highly eccentric outer planet the orbit of which crosses those of some of the inner planets. Strong planet-planet