Monomeric and dimeric cyclomaltodextrinases reveal different modes of substrate degradation
Two cyclomaltodextrinases (CDase) of thermophilic origin were investigated for their action on cyclodextrins. Although most CDases known today are made up of at least homodimers, one of the enzymes studied was shown to be a monomer in solution, while the other one was a dimer. Interestingly, the dimeric enzyme had a much superior selectivity for a cyclodextrin substrate compared to its monomeric h