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Validering av ny prognostisk modell i lymfkörtelnegativ bröstcancer baserad på automatiskt utvärderade DNA flödescytometriska data
Exploring health professionals´ experiences of being involved in a research project
The involvement of health professionals in research may ensure the acquisition of relevant and sustainable knowledge that is applicable in practice. However, knowledge is lacking about how professionals experience being involved. Therefore, the aim of this study was to explore how health professionals experienced the process of being involved in a project related to research on ageing and health.
Prolonged tamoxifen therapy; effects on contralateral breast cancer, endometrial cancer incidence and cardiovascular mortality
Involving professionals in research. In the field of ageing and health.
Involving professionals in research can ensure the acquisition of knowledge, that is relevant, applicable and sustainable. Professionals are people who work in health systems, or organisations that contribute to health systems, such as practitioners, managers or other decision-makers. They have context-specific knowledge which the researchers often lack. Therefore, when they are involved in resear
Learning Mechanisms for Retail Professionals: An Investigation of Warehouse workers, Procurement Officers, and Store Managers
The retail sector is facing fundamental transformations in nearly every part of the value chain, affecting the need for competence development in many retail professions. As most learning at work is informal and there is a deficit of studies of how such learning takes place in specific professions, systematized work with competence development is hampered. We therefore investigated the informal le
Weighing stars from birth to death : mass determination methods across the HRD
The mass of a star is the most fundamental parameter for its structure, evolution, and final fate. It is particularly important for any kind of stellar archaeology and characterization of exoplanets. There exist a variety of methods in astronomy to estimate or determine it. In this review we present a significant number of such methods, beginning with the most direct and model-independent approach
Estrogen receptor (ER)-beta has favorable independent prognostic value for ER-alfa negative breast cancer patients receiving adjuvant tamoxifen
Top Electrode Engineering for Freedom in Design and Implementation of Ferroelectric Tunnel Junctions Based on Hf1- xZrxO2
Ferroelectric tunnel junctions (FTJs) based on ultrathin HfO2 have great potential as a fast and energy-efficient memory technology compatible with complementary metal oxide semiconductors. FTJs consist of a ferroelectric film sandwiched between two distinct electrodes, the properties of which are intricately linked to the electrical properties of the FTJs. Here we utilize a W crystallization elec
Detection of HCl in a premixed H2/O2/Ar flame seeded with CHCl3 using mid-IR polarization spectroscopy
Mid-infrared polarization spectroscopy was applied to detect HCl at trace level in an atmospheric pressure premixed H2/O2/Ar flame with chloroform seeding. Detection sensitivity and potential interference from water lines was investigated.
A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen
Autoantigen discovery is a critical challenge for the understanding and diagnosis of autoimmune diseases. While autoantibody markers in current clinical use have been identified through studies focused on individual disorders, we postulated that a reverse approach starting with a putative autoantigen to explore multiple disorders might hold promise. We here targeted the epidermal protein transglut
The Influence of Postoperative Coronal Alignment on Tibial Migration After Total Knee Arthroplasty in Preoperative Varus and Valgus Knees : A Secondary Analysis of 10 Randomized Controlled Trials Using Radiostereometric Analysis
BACKGROUND: Orthopaedic surgeons aim for mechanical alignment when performing total knee arthroplasty (TKA) as malalignment is associated with loosening. Loosening may be predicted by migration as measured with radiostereometric analysis (RSA), but previous RSA studies on postoperative alignment have shown contradictory results and have been limited to cemented implants and small numbers of patien
COVID-19 pandemic and the great impulse to telemedicine : The basis of the WONCA Europe Statement on Telemedicine at the WHO Europe 70th Regional Meeting September 2020
Telemedicine is the use of telecommunication and information technologies to support the delivery of healthcare at a distance, guaranteeing patients healthcare by facilitating access where barriers exist; the COVID-19 pandemic has attracted worldwide interest in this field. The purpose of this paper is to highlight the main pros and cons of telemedicine, which serve as the basis of the WONCA Europ
TRPV1 har viktig roll i hjärnan
The discovery of TRPV1 as a receptor for capsaicin, the pungent ingredient in chili pepper, and noxious heat has triggered immense research on the role of TRP channels as polymodal receptors in sensory neuronal signaling. The rich abundance of TRPV1 in nociceptive primary afferents and its involvement in inflammatory and neuropathic pain encouraged the development of analgesics acting on TRPV1. Ho
3D gas-liquid interfaces and flow characteristics of two-phase flows in horizontal tubes
In order to investigate the characteristics of gas-liquid two-phase flows in horizontal mini circular tubes with inner diameters of 3.14 and 6.68 mm, a prism is adopted to improve the light path in the visualization experimental setup. The front and top views of air-water two-phase flow patterns in two tubes are captured synchronously based on the improved method. Three-dimensional gas-liquid inte
Time dependent effects of tamoxifen treatment on cardiovascular morbidity
Sediment Records Shed Light on Drivers of Decadal Iron Concentration Increase in a Boreal Lake
Increasing iron (Fe) concentrations are found in lakes on a wide geographical scale but exact causes are still debated. The observed trends might result from increased Fe loading from the terrestrial catchment, but also from changes in how Fe distributes between the water column and the sediments. To get a better understanding of the causes we investigated whether there has been any change in the
Central venous catheterisation - clinical studies on mechanical complications in the ultrasound-guided era
Central venous catheterisation is one of the most common invasive procedures performed on patients in secondary care. Unfortunately the catheterisation procedure is associated with mechanical complications that both can be life-threatening and may force postponement of life-saving treatments such as surgery and chemotherapy. The use of real-time ultrasound guidance increases success rates and redu
Informal care provision among male and female working carers : Findings from a Swedish national survey
INTRODUCTION: Informal carers in paid employment-working carers (WKCs)-have complex support needs. However, little is known about WKCs' pattern of informal care provision, the support they receive, the impact providing care has on their employment, and how these vary between male and female WKCs. This study describes the pattern of informal care provision and received support among Swedish WKCs.RE
Between the scientific and the alternative: women’s claims about copper toxicity caused by IUD use
The copper IUD is a widely used contraceptive, recommended to many women who want a long-acting contraceptive method and sometimes seen as an alternative for those who want to avoid side effects associated with hormonal alternatives. However, while many report being satisfied with their copper IUD, a growing number of women speak about a range of mental and physical symptoms believed to be caused
