We have previously identified C1 domain-containing phosphatase and TENsin homologue (C1-TEN) as being an intracellular binding partner for Axl receptor tyrosine kinase (RTK). C1-TEN is a tensin-related protein that houses an N-terminal region with predicted structural similarity to PTEN. Here, we report our observations on the effects of ectopic expression of C1-TEN in HEK293 cells, which resulted

Med hjälp av elva fallstudier undersöktes hur livskvaliteten hos funktionshindrade påverkas av tillgången till ortopedtekniska (OT) hjälpmedel och professionella insatser. Resultatet tyder på att det finns stora skillnader i insatser för samma funktionshinder och därmed kostnader mellan olika personer som får OT-hjälpmedel. Den som lever ett mer aktivt liv och t ex sportar får i regel mer avancera

Recension av Chris Rodleys intervjubok med David Cronenberg.

The gamma-decay of excited states in the neutron deficient isotopes Tc-87 and Tc-88 has been observed for the first time. The fusion-evaporation reactions Ni-58(S-32, p2n)Tc-87 and Ni-58(S-32, pn)Tc-88 at 110 MeV, Ca-40(Cr-50, p2n)Tc-87 and Ca-40(Cr-50, pn)Tc-88 at 170 MeV and Ni-58(Ar-36, alpha-pn)Tc-88 at 145 MeV beam energy were used. Unambiguous identification of these nuclei which are populat

Denna rapport är ett exempel på hur man utför en noggrann fuktdimensionering av en byggnad. Till vår hjälp har vi en checklista som ska användas i projekteringen. Den presenteras i FUKTDIMENSIONERING MED GENERELL CHECKLISTA i rapporten TVBH-3031. Generella checklistor syftar till att kontrollera alla fuktbelastningar under en byggnads brukstid så att inte byggnaden får skador eller andra olägehet

Using the Implicit Association Test, we investigate whether employers and students possess implicit and explicit negative attitudes and implicit perform-ance stereotypes toward Arab-Muslim men relative to native Swedish men. We also examine if employers and students have implicit and explicit performance stereotypes toward obese individuals relative to people of normal weight. The results demonstr

Objectives: Due to the increased diagnosis of prostate cancer at earlier stages and the overall increased use of hormone therapy, also in earlier disease stages, many patients will receive long-term hormone therapy. Therefore, the timing of initiating hormone therapy and the type of hormone therapy have become crucial items in the appropriate management of patients with prostate cancer. in additio

A recent new strategy for the transformation of mono-dioxolane protected 1,3-cyclohexadione into bridgehead hydroxyl bicyclo[2.2.2]octane derivatives, based on allylindation followed by ozonolysis and intramolecular aldol addition, was modified to include asymmetric allylindation. This enabled the first enantioselective synthesis of (1R,4R,6S)-endo-4-(tert-butyl-dimethyl-silyloxy)-6-hydroxy-bicycl

In the area of environment adaptations for people with physical disabilities, it is of vital importance that the design is optimized considering the human-environment interactions. All involved persons in such a planning process must be given sufficient support in understanding the information, so that everyone can participate actively. There is an apparent risk that discussions will be kept betwe

Development of autoimmune disease is the result of activation of the immune system that subsequently leads to tissue destruction. Although the clinical outcome significantly differs between autoimmune diseases, some pathogenic pathways could be shared. During the recent years, intense efforts to find the genetic factors behind development of the complex and polygenic autoimmune diseases have been

Radiolabelled monoclonal IgM rheumatoid factors, four from patients with type II essential cryoglobulinaemia and one originating from a patient with rheumatoid arthritis, were tested for binding to group A, B, C and G streptococci and Escherichia coli. Two of the preparations exhibited different binding patterns for the streptococci, whereas the remaining three were not reactive. The binding of on

This study has focused on structures formed through the release of lipid membrane material from milk fat globules. The aim of the study was to describe vesicles in the cream plasma and processing-induced vesicular structures in cream and buttermilk. The dairy samples were divided into three fractions through centrifugation, using DO for density control. These fractions were examined using cryogeni

The emissions of particles, and gaseous compounds, into the ambient air from biomass-fired moving grate boilers were characterized under different boiler operation conditions. The boilers had a thermal capacity of similar to1 MW. The flue gas cleaning systems consisted of multicyclones for the removal of coarse particles. Dry wood fuel that consisted of shavings, wood chips, and sawdust from a loc

In this paper, we propose a method for the estimation of the fundamental frequency of a periodic waveform based on the shift-invariance property of the sinusoidal signal model known from ESPRIT. An advantage of the proposed method is that the model order and the fundamental frequency can be found jointly and that the method does not depend on the density of the observation noise but rather on it b