A recursive algorithm is proposed for estimation of parameters in mixture models, where the observations are governed by a hidden Markov chain. The performance of the algorithm is studied by simulations of a symmetric normal mixture. The algorithm seems to be stable and produce approximately normally distributed estimates, provided the adaptive matrix is kept well conditioned.

The interaction between human papillomavirus (HPV) particles and cell surface heparan sulfate requires intact conformation of the HPV particles. Type-specific HPV serology is currently based on virus-like particles (VLPs) with intact conformation. Presence of incorrectly folded VLPs in VLP preparations is recognized as an important cause of cross-reactivity in HPV serology. Heparin-coated microtit

I formulate a simple model of the ultimatum game, in which a proposer and a responder can receive a reward if they agree on how to divide this reward between them. The model is easy to analyse and shows that strong tendencies to fair division are expected when evolution of strategy frequencies follow the traditional gradient dynamics assumed in evolutionary models. The mean stable offer is typical

We present some results on the existence of bounded positive solutions to a class of nonlinear second order ordinary diferential equations by using the Schauder-Ekhonov fixed point theorem. An application to the existence of bounded positive solutions to certain quasilinear elliptic equations in two-dimensional exterior domains is also given.

Levosimendan is a new agent for the treatment of acute heart failure. Levosimendan acts via complementary mechanisms; it enhances contractility by sensitising cardiac myofilaments to calcium and dilates blood vessels by opening ATP-dependent potassium channels. In contrast to traditional inotropes (beta-agonists or phosphodiesterase inhibitors), levosimendan does not raise myocyte calcium levels a

Aberrations in the G1/S checkpoint are common in malignancies and are probably important for tumor development. Few G1/S studies have been performed on renal cell carcinoma (RCC) and therefore in this study the cyclin D3 protein content in 80 RCCs and that in 12 corresponding normal kidney cortex tissues are characterized using Western blotting. High cyclin D3 protein content was observed in 16% o

Utvärderingen av Lyckebo solvärmeanläggnng med säsongslagring i öppet bergrum avslutades den 1 juli 1986. De värmeförluster som då konstaterades föranledde den uppföljning som denna rapport redovisar. Man försöker klarlägga orsakerna till avvikelser mellan beräknade och uppmätta värmeförluster och dra slutsatser för framtida projekt.

OBJECTIVE: To form a methodologic basis for DNA analysis of ductal carcinoma in situ (DCIS) and invasive carcinoma (IC) of the breast, including very small lesions, by comparison of flow cytometric (FCM) and image cytometric (ICM) methods for DNA quantitation. STUDY DESIGN: The material consisted of 41 DCIS lesions and 26 ICs. FCM DNA analysis of unfixed, frozen samples were compared to (1) FCM of

Objective: To investigate the influence of contextual and individual factors on self-reported psychological health. Design/setting/participants/measurements: The 2000 public health survey in Scania is a cross-sectional postal questionnaire study with a 59% participation rate. A total of 13,715 persons aged 18-80 answered the questionnaire. A multilevel logistic regression model, with individuals a

Most digital radiographic systems of today have wide latitude and are hence able to provide images with a small constraint on dose level. This opens up for an unprejudiced dose optimisation. However, in order to succeed in the optimisation task, good knowledge of the imaging and detection processes is needed. As a part of the European-wide research project 'unification of physical and clinical req

Intervju med George A Romero

Två tillämpningsexempel visar att den beskrivna fuktdimensioneringsmetoden är praktiskt genomförbar både när det gäller övergripande anvisningar (s k generella checklistor) för olika byggnadsdelar och för exakt definierade kontrollpunkter för en enskild byggnadsdelar (s k projekteringschecklista som redovisar ett oventilerat varmtak med papp eller dukar av gummi eller plast). De anvisningar som fi

The aim of this study was to review the research literature on pain and quality of life (QoL) and the relationship between these variables among people aged 75 years and above with rheumatoid arthritis and/or osteoarthritis. A Medline and CINAHL search was carried out using MeSH terms rheumatoid arthritis, osteoarthritis, QoL and pain in various combinations. Seventeen articles were identified tha

The doubly magic nucleus 100Sn represents a crucial test for the nuclear shell model, which is a widely used model for a quantitative description of nuclei. Excited states in 100Sn are experimentally not accessible with present day techniques, but it is possible to gain insight into its structure by studying the properties of excited states of neighboring nuclei. These nuclei are by themselves ver

We investigate the time scales of various dynamic processes during the evolution of the particle size distribution from its emission from a vehicle exhaust pipe through its dilution at kerbside and urban level. In addition, the situation in a road tunnel or near a highway is discussed. The derived formula framework allows the estimation of approximated time scales based on a given particle size di