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Miniaturized, Membrane-Based and Environmentally Green Sample Preparation Systems: Applications for Biological and Environmental Aqueous Samples

Contemporary advancements in miniaturization of analytical systems have advantageously fostered development, automation, and hyphenation of a variety of sample preparation techniques. Among several downscaled extraction designs, porous synthetic polymeric membranes (such as flat sheet (FS) or hollow fiber (HF)) have been utilized for membrane-based extraction, separating two aqueous phases (as in

Radiography and bone scintigraphy in osteoarthritis of the knee: comparison with MR imaging

Popular Abstract in Swedish Röntgen och isotopundersökning vid knäledsartros: en jämförelse med magnetkamera-undersökning Denna avhandling utgör en del av ett större forskningsprojekt om tidig artros (s.k. broskförslitning) i knäleden. Studien omfattar nästan 200 personer med knäsmärta, som när projektet startade 1990 var mellan 35 och 54 år. Vår avsikt är att under minst 10 års tid regelbundet uThe aim was to compare radiography of the tibiofemoral joint (TFJ) and the patellofemoral joint (PFJ), as well as bone scinigraphy with MR imaging in middle-aged individuals with chronic knee pain in the format of a prospective study of knee osteoarthritis. Individuals aged 35-54 years with chronic knee pain were identified. The prevalence of chronic knee pain was 15% (279/2000). Within this grou

Ultra low energy vs throughput design exploration of 65 nm sub-VT CMOS digital filters

This paper presents an analysis on energy dissipation of a digital half band filters operated in the the sub-threshold (sub-VT ) region with throughput constraints. The degradation of speed in the sub-VT domain is counteracted by unfolding the architectures. A filter is implemented in a basic 12-bit and its various unfolded structures. The designs are synthesized in a 65 nm low-leakage high-thresh

A social perspective on the interview technique in design research. Part II: The interview as a social situation

Many studies focusing on the design activity use the interview technique as a part of their investigation. Methodological discussions about the interview setting as the locus of a social interaction between the interviewer and the respondent and its implications for the interpretation of the obtained data are nevertheless rarely found in publications within our design community. Part I of this pub

Streptococcus pyogenes and its interactions with the human host

Popular Abstract in Swedish Streptococcus pyogenes Människan är ständigt koloniserad av en mängd olika mikroorganismer. De flesta bakterier är ofarliga och en del av dem är faktiskt nödvändiga för oss, t.ex. de tarmbakterier som hjälper oss att producera vitaminer. Grupp A streptokocker (GAS) eller Streptococcus pyogenes, är en av de vanligaste sjukdomsframkallande bakterierna hos människan. De kaWe have found that a set of group A streptococcal strains, primarily associated with skin infections, express surface-associated M proteins that bind plasminogen and plasmin with high affinity. The binding is mediated by a common 13 amino acid internal repeated sequence located in the NH2-terminal surface-exposed portion of these M proteins. It could be demonstrated that plasminogen, absorbed by t

Tryptophan-related Neurotransmission in the Brain: Disturbances Associated with Experimental Hepatic Encephalopathy

Popular Abstract in Swedish Tryptofan (TRP) är en s.k. essentiell aminosyra d.v.s. den kan inte syntetiseras av kroppen utan måste intas med födan. TRP ingår bl.a. som byggsten i kroppens proteiner men TRP används även som substrat för bildningen av signalsubstansen serotonin (även kallad 5-hydroxytryptamin; 5-HT). Dessutom kan TRP användas för bildningen av de för kroppen livsviktiga molekylerna In the present study, L-tryptophan (TRP)-related disturbances in the brain in experimental hepatic encephalopathy (HE) were investigated. The endogenous NMDA-receptor agonist and L-TRP metabolite quinolinic acid (QUIN) has been suggested to be involved in the pathogenesis of HE. We were, however, unable to detect any increases in QUIN levels in rats subjected to a chronic portacaval shunt (PCS) ei

Memory-Aware Feedback Scheduling of Control Tasks

This paper presents the incorporation of an auto-tuning real-time garbage collector into a feedback-based on-line scheduling system. The studied feedback scheduler is designed to dynamically adjust the sampling periods of a set of controller tasks in order to maximize the overall control performance. In the suggested approach, the memory management overhead is made explicit and taken into account