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Effect of red blood cell shape changes on haemoglobin interactions and dynamics : A neutron scattering study: Hb Interactions and Dynamics in RBCs

By using a combination of experimental neutron scattering techniques, it is possible to obtain a statistical perspective on red blood cell (RBC) shape in suspensions, and the inter-relationship with protein interactions and dynamics inside the confinement of the cell membrane. In this study, we examined the ultrastructure of RBC and protein-protein interactions of haemoglobin (Hb) in them using ul

Interleaflet Decoupling in a Lipid Bilayer at Excess Cholesterol Probed by Spectroscopic Ellipsometry and Simulations

Abstract: Artificial lipid membranes are often investigated as a replica of the cell membrane in the form of supported lipid bilayers (SLBs). In SLBs, the phase state of a lipid bilayer strongly depends on the presence of molecules such as cholesterol, ceramide, and physical parameters such as temperature. Cholesterol is a key molecule of biological membranes and it exerts condensing effect on lip

Visualisation of H2O2 penetration through skin indicates importance to develop pathway-specific epidermal sensing

Elevated amounts of reactive oxygen species (ROS) including hydrogen peroxide (H2O2) are observed in the epidermis in different skin disorders. Thus, epidermal sensing of H2O2 should be useful to monitor the progression of skin pathologies. We have evaluated epidermal sensing of H2O2 in vitro, by visualising H2O2 permeation through the skin. Skin membranes were mounted in Franz cells, and a suspen

Completion of radical hysterectomy does not improve survival of patients with cervical cancer and intraoperatively detected lymph node involvement : ABRAX international retrospective cohort study

Background: The management of cervical cancer patients with intraoperative detection of lymph node involvement remains controversial. Since all these patients are referred for (chemo)radiation after the surgery, the key decision is whether radical hysterectomy should be completed as originally planned, taking into account an additional morbidity associated with extensive surgical dissection prior

Family members' experiences of everyday life when a child is dependent on a ventilator : A metasynthesis study

Children using mechanical ventilation for survival represent a small, but growing, vulnerable population in society. The aim of this study was to describe the existing qualitative research that examined family members' experiences when a child is dependent on ventilator at home. A metasynthesis is an interpretative integration of qualitative research findings based on a systematic literature searc

The experiences of patients and their families of visiting whilst in an intensive care unit - A hermeneutic interview study

Aim: The aim of this study was to interpret and understand the meanings of the lived experiences of visiting of patients in an ICU and their families. Method: The research design was hermeneutic, based on interviews. This study includes 12 interviews with seven patients and five relatives who had been in an ICU. The interview text was interpreted in a Gadamerian manner as different plays with acto

Lund critical library studies – a new research group

We argue that there is a need for a more elaborate and sophisticated discussion of if, and then how, the public library fulfils its social role to con- tribute to democracy. Therefore, we have formed the Lund Critical Library Studies group with a shared interest of contributing to a more nuanced and rich discussion about public libraries. This allows us to engage in discussions on how the library

Impact of monocytic cells on recovery of uncultivable bacteria from atherosclerotic lesions

Objective. Epidemiological evidence suggests that infections may contribute to atherogenesis. However, with the exception of Chlamydophila pneumoniae, cultivable bacteria have not been recovered from atherosclerotic lesions. Therefore, we aimed at developing an approach to recover uncultivable bacteria from atherectomy tissues. Methods. We cultured homogenates from atherectomy specimens from seven

Geoelectrical monitoring of embankment dams for detection of anomalous seepage and internal erosion - experiences and work in progress in Sweden

The demand for better methods for condition control and monitoring of embankment dams will increase in a near future as a result of expected more extreme weather situations. Furthermore the availability demand on hydropower will increase as a result of switching from fossil fuels to wind and solar power, in some countries in combination with decommissioning of nuclear power. Temperature monitoring

Maximising and maintaining social value in the long term – the influence of embeddedness in addressing organisational challenges following Social Enterprise growth

Polanyi argued that throughout history the economy was embedded in society, serving as a tool to make provision for societies’ needs; but in capitalist market economies the market dominates the system, subordinating society to its work (Polanyi, 2001). Although social enterprise offers potential for re-embedding the economy into serving society (Roy & Hackett, 2017), balancing competing social

Autonomy of the EU Legal Order: A Concept in Need of Revision?

The issuing of Opinion 2/13 on the European Union’s (EU’s) accession to the European Convention on Human Rights by the Court of Justice of the EU (CJEU), followed by Case C- 284/16 Achmea and Opinion 1/17 on the compatibility with EU law of the Comprehensive Economic and Trade Agreement between Canada and the European Union (CETA), brought the concept of the autonomy of the EU legal order to the p

Towards returns management strategies in internet retailing

The digital transformation of the retailing industry in recent years has had a profound effect on consumers’ behaviour on a global scale. When shopping and browsing online, consumers are not able to “touch and feel”, which means that product returns are inevitable. The fashion industry has particularly suffered from high return rates, which fluctuate between 30% and 50%. The industry has been stru