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Today, it is often said that we stand at the opening of a postindustrial “knowledge society,” where private enterprise has become increasingly dependent on research and innovation and where education has become a prerequisite for success on the labor market. This idea serves as a source of inspiration when governments, corporations and institutions elaborate policies and strategies for future deve
Popular Abstract in Swedish Kroppens rörelser åstadkommes genom sammandragning av muskelvävnad som kan vara av två slag, glatt eller tvärstrimmig. Den senare sorten kan indelas i skelett och hjärtmuskulatur, vilka har mycket olika egenskaper trots den gemensamma benämningen. Muskelvävnaden är uppbyggd av långsträckta, spolformade celler som innehåller tunna och tjocka kontraktila filament, beståenThe initial signal for contraction in smooth muscle is an increase in [Ca2+]i. Ca2+ ions can either enter the cytosol from the extracellular medium or be released from intracellular stores. Voltage-operated Ca2+ channels (VOC) play a dominant role in the activation of smooth muscle contraction. This thesis describes two novel regulatory mechanisms of the dihydropyridine (DHP)-sensitive VOC in smoo
Knowledge of the current distribution on a radome can be used to improve radome design, detect manufacturing errors, and to verify numerical simulations. In this paper, the transformation from near-field data to its equivalent current distribution on a surface of arbitrary material, ie the radome, is analyzed. The transformation is based on a vector surface integral representation that relates the
This Index is the first global analysis of corruption risk in defence establishments worldwide. We aim to give governments, armed forces, civil society and citizens the tools to avoid the dangers and inefficiencies that corruption in defence brings.
The objective of this work was to study the formation of DNA-cationic vesicle complexes (lipoplexes). These complexes are interesting not only from a fundamental point of view but also as promising candidates for gene therapy. The approach taken was to study first the cationic vesicles by themselves. This will allow us to better understand the "complexation mechanism" upon the addition of DNA. The
This book brings into question the dichotomies inherent in the sociology of law. It is a journey in search of a method capable of taking us beyond the theoretical limitations imposed on socio-legal research by sharply defined divisions such as “law on the books” and “law in action”, “formal” and “informal law”, “facts” and “norms”, “form” and “substance”, “internal” and “external” legal cultures o
It is well documented that the antitumour activity of the Pt(II)-complex cisplatin, and similar anticancer active complexes, is a result of metalation of DNA, and thereby inhibition of cell proliferation. Since nucleic acids are polyanions at physiological pH, the rate of adduct formation with positively charged complex, as the hydrolyzed Pt(II) complexes studied in this work, is influenced by the
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Our aim was to evaluate if there is a benefit in diagnostic accuracy and efficiency of viewing breast tomosynthesis (BT) image volumes presented horizontally oriented, but also to evaluate the use of a systematic search strategy where the breast is divided, and analyzed consecutively, into two sections. These image presentations were compared to regular vertical image presentation. All methods wer
Popular Abstract in Swedish En ny metod för att syntetisera avancerade kolhydrater har utvecklats. I en utvärdering har två kolhydratstrukturer, viktiga intermediat i ett nytt cancervaccin, syntetiserats.A novel promoter system IX/AgOTf (X=Cl or Br) for thioglycoside activation has been developed (paper I-II). The promoter system has been evaluated in the synthesis of two GD3 bis-lactam fragments (paper III).
