In this work the syntheses, structure and SOD activity of covalently grafted Fe(III)-complexes formed with various N- or C-protected amino acid ligands (L-histidine and L-tyrosine) inspired by the active site of the Fe SOD enzyme are presented. Chloropropylated silica gel was used as support to mimic the proteomic skeleton of the enzyme. Anchored complexes having uniform amino acids as well as the

The cysteine proteinase inhibitor cystatin C inhibited RANKL-stimulated osteoclast formation in mouse bone marrow macrophage cultures, an effect associated with decreased mRNA expression of Acp5, Calcr, Ctsk, Mmp9, Itgb3, and Atp6i, without effect on proliferation or apoptosis. The effects were concentration dependent with half-maximal inhibition at 0.3 M. Cystatin C also inhibited osteoclast form

Four unconjugated diimine palladium complexes have been synthesized, and spectroscopically and structurally characterized. All four palladium complexes were used as catalysts in the Heck coupling reaction between iodobenzene and methyl acrylate or butyl acrylate with very good conversion to either methyl (2E)-3-phenylacrylate or butyl (2E)-3-phenylacrylate.

The endothelium lining the vascular lumen is continuously exposed to complement from the circulation. When erroneously activated on host cells, complement may generate a deleterious effect on the vascular wall leading to endothelial injury, exposure of the subendothelial matrix and platelet activation.In this review the contribution of complement activation to formation and maintenance of the path

Background: The Medical Outcomes General Health Survey (SF-36) is a widely used health status measure; however, limited evidence is available for its performance in orthopedic settings. The aim of this study was to examine the magnitude and meaningfulness of change and sensitivity of SF-36 subscales following orthopedic surgery. Methods: Longitudinal data on outcomes of total hip replacement (THR,

Three species of bradoriid arthropods from the lower to middle Cambrian transitional interval of Scania, southern Sweden, are described and illustrated: Beyrichona tines from the top of the traditional lower Cambrian (Gislov Formation: Ornamentaspis? linnarssoni Zone), and Hipponicharion eos and Alutella sp. from the basal portion of the traditional middle Cambrian (lowermost part of the Alum Shal

The brick kiln at Saltsjö Boo is one of very few such structures known from medieval Sweden. Approx ¾ of the kiln has been excavated in successive short excavations from 2006 to 2011. Carbon 14 and TL (Thermoluminiscence) analyses indicate that the kiln has been in operation from c. 1250 to c.1450. This paper presents the results of the excavations and discusses the production of bricks and indust

This study uses continuously logged driving data from 166 private cars to derive the level of jerks caused by the drivers during everyday driving. The number of critical jerks found in the data is analysed and compared with the self-reported accident involvement of the drivers. The results show that the expected number of accidents for a driver increases with the number of critical jerks caused by

In Swedish higher formal aesthetic education, students from ethnic minorities are significantly underrepresented. This also seems to be the case in music education for younger children. Accordingly, the relationship between music education and the ethnic diversity of the contemporary Swedish society, not reflected in the selection of students to the Swedish music and culture schools, is of vital iIn Swedish higher formal aesthetic education, students from ethnic mi-norities are significantly underrepresented. This also seems to be the case in music education for younger children. Accordingly, the relation-ship between music education and the ethnic diversity of the contem-porary Swedish society, not reflected in the selection of students to the Swedish music and culture schools, is of vita

We report on the fabrication of InAs nanowires coupled to superconducting leads with high critical current and widely tunable conductance. We implemented a double lift off nanofabrication Method to get very short nanowire devices with Ohmic contacts. We observe very high critical. currents of up to 800 nA in a wire with a diameter of 80 nm. The current- voltage characteristics of longer and suspen

Background and objective: The pharmacokinetics of mycophenolic acid (MPA) are complex, with large interindividual variability over time. There are also well documented interactions with ciclosporin, and assessment of MPA exposure is therefore necessary when reducing or stopping ciclosporin therapy. Here we report on the pharmacokinetic and pharmacodynamic behaviour of MPA in renal transplant patie

Popular Abstract in Swedish Ett grundantagande för avhandlingen Klassrummet som muntlig arena. Att bygga och etablera ethos är att en människa som med trovärdighet vill kunna verka som en demokratisk medborgare i olika kommunikationssituationer måste besitta kommunikativ kompetens. Följaktligen hänger demokrati och kommunikativ kompetens tätt samman. En viktig trovärdighetsfaktor i sammanhanget ärThe Class Room as an Oral Arena: Building and Establishing Ethos starts with the premise that every person who wants to act credibly as a democratic citizen must have a communicative competence. Democracy and communicative competence are closely linked. To communicate credibly is to communicate with ethos. The purpose of this dissertation is to study how students in Swedish gymnasium build and est

Bombus terrestris is one of the most commonly used insect models to investigate visually guided behavior and spatial vision in particular. Two fundamental measures of spatial vision are spatial resolution and contrast sensitivity. In this study, we report the threshold of spatial resolution in B. terrestris and characterize the contrast sensitivity function of the bumblebee visual system for a dua

Color affects us both consciously and subconsciously, and can create actions and reactions: biological (colorful males to attract females in the animal world), psychological (the use of warm colors or cool colors to effect a specific mood), symbolic (specific colors for weddings and mourning), religious (blue, saffron), emotional (expressionism in art), social (pink and blue infant clothing) or pu

Background: Substance use disorders and complications, such as drug overdose (OD) and suicide attempt (SA), are common among criminal justice clients. Methods: Since 2001, the Swedish Prison and Probation Service has assessed substance-using clients with the Addiction Severity Index (ASI), a semi-structured instrument widely used to examine substance-related problems in different domains of life.

The onset of cellular instability in adiabatic H-2/O-2/N-2 premixed flames anchored to a heat-flux burner is investigated numerically. Both hydrodynamic instability and diffusional-thermal instability are shown to play an important role in the onset of cellular flames. The burner can effectively suppress cellular instability when the flames are close to the burner, otherwise the burner can suppres

Objective: The aim of this study was to identify young women's ideal images of sexual situations and expectations on themselves in sexual situations. Study design: We conducted audio-taped qualitative individual interviews with 14 women aged 14 to 20 years, visiting two youth centers in Sweden. Data were analysed with constant comparative analysis, the basis of grounded theory methodology. Results