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Prevalence of thyroid autoimmunity in children with celiac disease compared to healthy 12-year olds.

Objectives. Studies have suggested a correlation between untreated celiac disease and risk for other autoimmune diseases. We investigated the prevalence of thyroid autoimmunity in 12-year-old children (i) with symptomatic celiac disease diagnosed and treated with a gluten-free diet, (ii) with screening-detected untreated celiac disease, and (iii) without celiac disease. Methods. Blood samples from

Signaling mechanisms in Streptococcal M1 proteininduced inflammation and injury in the lung

Streptococcus pyogenes of the M1 serotype is frequently associated with severe streptococcal infections. Acute lung injury is recognized as a key component in the pathophysiology of streptococcal M1 proteininduced inflammation. Numerous reports have demonstrated that excessive infiltration of neutrophils is a rate-limiting step in septic lung damage. We observed that targeting neutrophil functions

Metaforer och materialiseringar. Om apor hos Vladimir Nabokov och Sara Stridsberg

By tradition the humanities have been anthropocentrically focused on the lives of human beings in arts and literature. The limited analysis of what other species do in literature – and of the different relations between humans and animals that are represented – has sustained the notion of a hierachical divide between humans and other species, thereby reducing the ethical potential of literature to

Structural and magnetic properties of nanoclusters in GaMnAs granular layers

Structural and magnetic properties of GaAs thin films with embedded nanoclusters were investigated as a function of the annealing temperature and Mn content. Surprisingly, the presence of two kinds of nanoclusters with different structure was detected in most of the samples independently of the thermal processing or Mn content. This proved that the presence of a given type of clusters cannot be as

Search for massive colored scalars in four-jet final states in root s=7 TeV proton-proton collisions with the ATLAS detector

A search for pair-produced scalar particles decaying to a four-jet final state is presented. The analysis is performed using an integrated luminosity of 34 pb(-1) recorded by the ATLAS detector in 2010. No deviation from the Standard Model is observed. For a scalar mass of 100 GeV (190 GeV) the limit on the scalar gluon pair production cross section at 95% confidence level is 1 nb (0.28 nb). When

Honeybee navigation: critically examining the role of the polarization compass

Although it is widely accepted that honeybees use the polarized-light pattern of the sky as a compass for navigation, there is little direct evidence that this information is actually sensed during flight. Here, we ask whether flying bees can obtain compass cues derived purely from polarized light, and communicate this information to their nest-mates through the 'waggle dance'. Bees, from an obser

Sunnybrook and House-Brackmann Systems in 5397 Facial Gradings

Objectives. To study the correlation between Sunnybrook and House-Brackmann facial grading systems at different time points during the course of peripheral facial palsy. Study Design. Prospective multicenter trial. Setting. Seventeen otorhinolaryngological centers. Subjects and Methods. Data are part of the Scandinavian Bell's palsy study. The facial function of 1920 patients with peripheral facia

Regulation of Autoimmunity and Inflammation by microRNAs and Environmental Factors

Tolerance is crucial for maintaining immunological balance and avoid autoimmune diseases like type 1 diabetes and the inflammatory bowel disease, ulcerative colitis (UC). In Study I, we have investigated the regulatory role of a class of noncoding RNAs, the miRNAs, during thymocyte development of the where central tolerance is established. We used the non-obese diabetic mouse (NOD) which is spon

Smooth 2-D frequency estimation using covariance fitting

In this paper, we introduce a non-parametric 2-D spectral estimator for smooth spectra, allowing for irregularly sampled measurements. The estimate is formed by assuming that the spectrum is smooth and will vary slowly over the frequency grids, such that the spectral density inside any given rectangle in the spectral grid may be approximated well as a plane. Using this framework, the 2-D spectrum

Elementary and macroscopic light-induced currents and their Ca(2+)-dependence in the photoreceptors of Periplaneta americana

In a microvillar photoreceptor, absorption of an incident photon initiates a phototransduction reaction that generates a depolarizing light-induced current (LIC) in the microvillus. Although in-depth knowledge about these processes in photoreceptors of the fruitfly Drosophila is available, not much is known about their nature in other insect species. Here, we present description of some basic prop

Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3 '-sulfo-lactose, and 2 '-fucosyllactose

Galectin-4 is a tandem-repeat galectin with two distinct carbohydrate recognition domains (CRD). Galectin-4 is expressed mainly in the alimentary tract and is proposed to function as a lipid raft and adherens junction stabilizer by its glycan cross-linking capacity. Galectin-4 plays divergent roles in cancer and inflammatory conditions, either promoting or inhibiting each disease progression, depe

Long-term sustained remission in a cohort study of patients with rheumatoid arthritis: choice of remission criteria.

Remission is a widely accepted goal for treatment of rheumatoid arthritis (RA) but has to be sustained to arrest joint damage and disability. However, appropriate criteria for the assessment of sustained remission in long-term studies are not established. Therefore, we have compared the disease activity score calculated on 28 joints (DAS28) remission criterion, the Simplified Disease Activity Inde

Social capital, desire to increase physical activity and leisure-time physical activity: A population-based study.

OBJECTIVES: To investigate the associations between social capital (trust) and leisure-time physical activity. STUDY DESIGN: The 2004 Public Health Survey in Skåne is a cross-sectional study. METHODS: In total, 27,757 individuals aged 18-80 years answered a postal questionnaire (59% participation). Logistic regression models were used to investigate the associations between trust, desire to incr

Non-work at work : Resistance or what?

Based on 43 interviews conducted with employees who spend around half of their working-hours on non-work related activities such as cyberloafing', a typology of empty labour is suggested according to sense of work obligation and potential output in order to set the phenomenon of workplace time-appropriation into a theoretical context in which wasteful aspects of organization and management are tak

Formal subdivision of the Holocene Series/Epoch: a Discussion Paper by a Working Group of INTIMATE (Integration of ice-core, marine and terrestrial records) and the Subcommission on Quaternary Stratigraphy (International Commission on Stratigraphy)

This discussion paper, by a Working Group of INTIMATE (Integration of ice-core, marine and terrestrial records) and the Subcommision on Quaternary Stratigraphy (SQS) of the International Commission on Stratigraphy (ICS), considers the prospects for a formal subdivision of the Holocene Series/Epoch. Although previous attempts to subdivide the Holocene have proved inconclusive, recent developments i

Prospective analysis of neuropsychiatric events in an international disease inception cohort of patients with systemic lupus erythematosus

Objectives To determine the frequency, accrual, attribution and outcome of neuropsychiatric (NP) events and impact on quality of life over 3 years in a large inception cohort of patients with systemic lupus erythematosus (SLE). Methods The study was conducted by the Systemic Lupus International Collaborating Clinics. Patients were enrolled within 15 months of SLE diagnosis. NP events were identifi