Clonality studies of mature cells suggest that the primary transformation event in myelodysplastic syndrome (MDS) most frequently occurs in a myeloid-restricted progenitor, a hypothesis supported by recent studies of purified CD34(+)Thy1(+) hematopoietic stem cells (HSCs) in cases with trisomy 8 (+8). In contrast, we recently demonstrated that a lymphomyeloid HSC is the target for transformation i

The emission time chronology of neutrons, protons, and deuterons from the E/A=61 MeV Ar-36+Al-27 reaction is deduced from two-particle correlation functions.

Methods for planning and control of the flow of material in the manufacturing enterprise are more or less appropriate to use in a specific situation, mainly depending on the existing planning environment. How well they contribute to an effective material flow is also depending on how they are applied. This paper examines which material planning methods companies are using, to what extent these met

We studied the structure of genetic variation (at both ramet- and genet-level) and clonal diversity within and among populations in the four closely related arctic clonal sedges Carex bigelowii, C. ensifolia, C. lugens and C. starts by use of allozyme markers. Compared to other sedges and arctic plants, the studied taxa all had high levels of genetic variation, both within populations and taxa. Th

A system is developed that from an image sequence of a deformable object automatically extracts features and tracks them through the sequence, estimates the non-rigid 3D structure and finally computes a surface triangulation. Also the camera motion is acquired. The object is supposed to deform according to a linear model, while the motion of the camera can be arbitrary. No domain specific prior of

We present estimates of standardized selection (directional and quadratic) differentials via reproductive success on eight morphological traits in a newly founded long-term study population of great reed warblers Acrocephalus arundinaceus in Sweden. In order to predict the evolutionary response to selection in these traits we present estimates of heritabilities (h(2)), phenotypic (r(P)) and geneti

OBJECTIVE: The aim of this study was to describe the distributions of major extracellular matrix components, such as proteoglycans, collagen acid hyaluronan, in the fetal membranes at term. STUDY DESIGN: Fetal membranes were obtained from elective cesarean deliveries at term. Guanidinium extracts were analyzed for proteoglycans with alcian blue precipitation, sodium dodecyl sulfate-polyacrylamide

Purpose: This trial of the German High-Grade Non-Hodgkin's Lymphoma Study Group compares the use of high-dose therapy (HDT) as part of primary treatment with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) plus etoposide followed by involved-field (IF) radiotherapy in a randomized, multicenter, phase III study. Patients and Methods: Three hundred twelve patients with "aggressive"

Through the past decades, new medical devices have been introduced at an increasing pace at the urge primarily of manufacturers, clinicians, and patients. Whereas it is mandatory to assess and approve new pharmaceuticals before their widespread use is allowed, innovations in medical devices generally have not been subject to the smae restrictions. The European Communitys program on completion of t

Today, shortened lead-times in the automotive industry have raised requirements on rapid information exchange. The increased use and access to the Internet have created possibilities to transfer information to people independent of location. This development, together with the increased speed in the portable computer technology, has opened possibilities for bringing results from sheet-metal-formin

The mean effective gain (MEG) is one of the most important parameters for the characterisation of antennas in wireless channels. An analysis of some fundamental properties of the MEG is provided and corresponding physical interpretations are given. Three points are analysed in detail: (i) closed-form expressions for MEG in a mixed environment with both stochastic and deterministic components are p

The aim of this article is to explore how retail store image is perceived by consumers from different cultural backgrounds and with different degrees of awareness and experience of the retailer. The subject is IKEA, a retailer recognized as having a global approach to the markets in which it operates, resulting in a highly standardized approach to store branding. However, rather than employing tra

Impact assessment (IA) is an instrument that is gradually making inroads into European Union policy making. Great ambitions are tied to the introduction of a compulsory system of IA as a way to achieve better regulation but also as a tool to improve legitimacy of government and increase unity in European politics. In order to raise the quality of the assessments, which has been questioned, there i

A festival report from Lund International Fantastic Film Festival 2005

Three well-known dynamic acidification models (MAGIC, SAFE, SMART) were applied to data sets from five Integrated Monitoring sites in Europe. The calibrated models were used in a policy-oriented framework to predict the long-term soil acidification of these background forest sites, given different scenarios of future deposition of S and N. Emphasis was put on deriving realistic site-specific scena

Purpose: To demonstrate the feasibility of a novel technique that modifies the configuration of a thoracic stent-graft after deployment to comply with the arch curvature. Technique: The principle of a Bowden cable has been applied to direct a conventional thoracic stent-graft in situ after deployment. A suture placed at the proximal inner curve of a conventional thoracic stent-graft is fitted with

Given the great range of visual systems, tasks and habitats, there is surprisingly little experimental evidence of how visual limitations affect behavioural strategies under natural conditions. Analysing this relationship will require an experimental system that allows for the synchronous measurement of visual cues and visually guided behaviour. The first step in quantifying visual cues from an an