Patch testing with serial dilutions of various isothiazolinones in patients hypersensitive to methylchloroisothiazolinone/methylisothiazolinone.
In 2005, methylisothiazolinone (MI) on its own came into use as a preservative. Prior to that, MI was always present together with methylchloroisothiazolinone (MCI). Can the pattern of reactivity to the separate active ingredients in allergic patients tell us something about the primary sensitizer?
