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Choroid plexus-cerebrospinal fluid route for monocyte-derived macrophages after stroke

Background: Choroid plexus (CP) supports the entry of monocyte-derived macrophages (MDMs) to the central nervous system in animal models of traumatic brain injury, spinal cord injury, and Alzheimer's disease. Whether the CP is involved in the recruitment of MDMs to the injured brain after ischemic stroke is unknown. Methods: Adult male C57BL/6 mice were subjected to focal cortical ischemia by perm

Enablers and barriers to project planning and scheduling based on construction projects in Oman

While the concepts of planning and scheduling seem to be adequately discussed in the project management literature, relatively few examples of factors specifically affecting the performance of planning and scheduling are to be found. The study reported in this paper investigated a set of factors identified as enablers and barriers to successful project planning and scheduling of construction proje

Assessment of effect of ductile tearing on cleavage failure probability in ductile to brittle transition region

The fracture behaviour of ferritic and ferritic martensitic steels in ductile to brittle transition (DBT) region has been extensively studied in recent years and a probabilistic approach of master curve method is generally used to describe the fracture toughness of BCC steels in DBT region as a function of temperature. The assessment of cleavage failure probability however is still untouched in th

Ultrafast Electron Dynamics in Solar Energy Conversion

Electrons are the workhorses of solar energy conversion. Conversion of the energy of light to electricity in photovoltaics, or to energy-rich molecules (solar fuel) through photocatalytic processes, invariably starts with photoinduced generation of energy-rich electrons. The harvesting of these electrons in practical devices rests on a series of electron transfer processes whose dynamics and effic

Banks and Swedish financial crises in the 1920s and 1930s

Financial crises occur at regular and unpredictable moments in capitalist economies. However, an absence of shared theoretical approaches to and even definitions of the subject still plague the analysis of financial crises. This situation makes historical analysis even more important. This article compares two Swedish financial crises, one in the 1920s and the other in the 1930s. The comparison sh

How deformed are the TSD bands in odd Lu isotopes?

The experimental fingerprints for large deformation in the triaxial strongly deformed (TSD) bands of 163,165,167Lu are discussed. It is argued that these fingerprints are not very convincing. On the contrary, especially the fact that there exist strong interactions between the TSD bands and normal-deformed (ND) bands indicates that the deformation of the TSD bands cannot be very different from tha

Nursing care for stroke patients : A survey of current practice in eleven European countries

AIMS AND OBJECTIVES: To conduct a survey of the clinical nursing practice in European countries in accordance with the European Stroke Strategies (ESS) 2006, and to examine to what extent the ESS have been implemented in stroke care nursing in Europe.BACKGROUND: Stroke is a leading cause of death and disability globally. Optimal organisation of interdisciplinary stroke care is expected to ameliora

Is ambient heat exposure levels associated with miscarriage or stillbirths in hot regions? A cross-sectional study using survey data from the Ghana Maternal Health Survey 2007

It is well established that high ambient heat could cause congenital abnormalities resulting in miscarriage or stillbirth among certain species of mammals. However, this has not been systematically studied in real field settings among humans, despite the potential value of such knowledge for estimating the impact of global warming on the human species. This study sought to test the hypothesis that

Evolution of sociality in spiders leads to depleted genomic diversity at both population and species levels

textcopyright 2017 John Wiley Sons Ltd.Across several animal taxa, the evolution of sociality involves a suite of characteristics, a "social syndrome," that includes cooperative breeding, reproductive skew, primary female-biased sex ratio, and the transition from outcrossing to inbreeding mating system, factors that are expected to reduce effective population size (Ne). This social syndrome may be

Antibody heavy chain variable domains of different germline gene origins diversify through different paths

B cells produce antibodies, key effector molecules in health and disease. They mature their properties, including their affinity for antigen, through hypermutation events; processes that involve, e.g., base substitution, codon insertion and deletion, often in association with an isotype switch. Investigations of antibody evolution define modes whereby particular antibody responses are able to form

The XMM deep survey in the CDF-S : X. X-ray variability of bright sources

Aims. We aim to study the variability properties of bright hard X-ray selected active galactic nuclei (AGN) in the redshift range between 0.3 and 1.6 detected in the Chandra Deep Field South (XMM-CDFS) by a long (∼3 Ms) XMM observation. Methods. Taking advantage of the good count statistics in the XMM CDFS, we search for flux and spectral variability using the hardness ratio (HR) techniques. We al

Dosimetry-based treatment planning for molecular radiotherapy : A summary of the 2017 report from the Internal Dosimetry Task Force

Background: The European directive on basic safety standards (Council directive 2013/ 59 Euratom) mandates dosimetry-based treatment planning for radiopharmaceutical therapies. The directive comes into operation February 2018, and the aim of a report produced by the Internal Dosimetry Task Force of the European Association of Nuclear Medicine is to address this aspect of the directive. A summary o

Switching Molecular Conformation with the Torque on a Single Magnetic Moment

For the endohedral fullerene molecule HoLu2N@C80, it is shown that the endohedral HoLu2N unit may be oriented in a magnetic field. The Ho magnetic moment is fixed in the strong ligand field and aligns along the holmium-nitrogen axis. The torque of a magnetic field on the Ho magnetic moment leads to a hopping bias of the endohedral unit inclining to an orientation parallel to the externally applied

Control theory for software engineering : Technical briefing

Pervasiveness and complexity of modern software are challenging engineers to design applications able to guarantee the desired quality of service despite unpredictable runtime variations in their execution environment. A variety of techniques have been proposed in the last year for the design of self-adaptive applications; however, most of them is tailored to specific applications or can provide l

Protective and Nanoporous Alumina Films Studied in situ by X-ray and Electrochemical Methods

Aluminium och Aluminiumlegeringar, som förutom aluminium innehåller några få procent av andra metaller, används i flera olika produkter såsom mobiltelefoner, flygplan, bilar och byggnader. Bland annat är aluminiumlegeringar det mest använda byggtekniska materialet efter järnlegeringar. Det breda användandet av aluminiumlegeringar förklaras av de många fördelaktiga egenskaperna. Till exempel har leIn this thesis, the studies of native and anodic oxides on both aluminum model single crystal surfaces as well as on aluminum alloys found in applications are presented. The focus has been on the characterization in situ as the oxide is growing by an electrochemical process called anodization. For the investigations, a combination of various X-ray scattering and spectroscopy methods, as well as el