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Ultrasound Assisted Alkaline Pre‐treatment Efficiently Solubilises Hemicellulose from Oat Hulls

The establishment of sustainable bioeconomies requires the utilization of new renewable biomaterials. One such material currently seen as a waste product is oat hulls. Oat hulls exhibit a great potential for the production of dietary fibres due to their exceptionally large hemicellulose content (35%). Their recalcitrant structure however requires a suitable pre-treatment method to access and proce

New Kids on the Block : The Emerging Role of YAP/TAZ in Vascular Cell Mechanotransduction

YAP and TAZ are transcriptional coactivators controlled by the Hippo signaling pathway and by actin dynamics, and that are critical for cell growth and organ size control. YAP and TAZ are exquisitely sensitive to mechanical cues, such as substrate stiffness and shear stress, and the realization is growing that they play roles in arterial remodeling and aneurysm formation. This chapter discusses ho

Boronic Acid Functionalized Nanosilica for Binding Guest Molecules

Dendritic fibrous nanosilica (DFNS) has very high surface area and well-defined nanochannels; therefore, it is very useful as supporting material for numerous applications including catalysis, sensing, and bioseparation. Due to the highly restricted space, addition of molecular ligands to DFNS is very challenging. This work studies how ligand conjugation in nanoscale pores in DFNS can be achieved

How to detect late-onset inborn errors of metabolism in patients with movement disorders - A modern diagnostic approach

We propose a modern approach to assist clinicians to recognize and diagnose inborn errors of metabolism (IEMs) in adolescents and adults that present with a movement disorder. IEMs presenting in adults are still largely unexplored. These disorders receive little attention in neurological training and daily practice, and are considered complicated by many neurologists. Adult-onset presentations of

The genus eriastichus la salle (Hymenoptera, eulophidae, tetrastichinae) in the neotropical region, introducing 48 new species

Our knowledge of the recently described genus Eriastichus La Salle is greatly enhanced with the addition of 48 new species: E. acribis sp. nov., E. aphritis sp. nov., E. cluridis sp. nov., E. coelotis sp. nov., E. co-lenis sp. nov., E. copalensis sp. nov., E. daptilis sp. nov., E. decoris sp. nov., E. denotatis sp. nov., E. derilis sp. nov., E. diadrys sp. nov., E. dotaensis sp. nov., E. drupis sp

Blue tit Cyanistes caeruleus males increase their reproductive effort when subject to a flea experimental manipulation

Parasites exert a strong selection pressure on their hosts as manifested in behavioural antiparasite traits to reduce negative impacts on fitness. The numerous nest-dwelling ecto-parasites residing in avian nests make altricial birds excellent model-systems for investigating the relationship between parasites and their hosts. Here, we experimentally increased natural levels of hen fleas Ceratophyl

The exercise of discretion in international law – why constraining criteria have a proper place in the analysis of legal decision-making

In international law, the exercise of legal discretion is constrained by criteria, such as the abuse of rights doctrine and the principle of legal certainty. The hitherto research of these criteria gives reason to take up a discussion on the appropriate way of conceptualising discretion and constraining criteria. This article, in contrast to the belief of other scholars, makes a case for the under

Radical trachelectomy

Radical trachelectomy is the cornerstone' of fertility-sparing surgery in patients with early-stage cervical cancer wishing to preserve fertility. Growing evidence has demonstrated the oncologic safety and subsequent favorable pregnancy outcomes in well-selected cases. In the absence of prospective trials, the decision on the appropriate surgical approach (vaginal, open, or minimally invasive surg

The perils of authentic leadership theory

In this commentary, we discuss perils of authentic leadership theory (ALT) in a modest effort to help weed out one theory that has gone amiss to pave the way for new ideas. We make an argument for why ALT is not only wrong in a harmless manner, but it may be outright perilous to leadership scholars, scholarship and those who believe in it. It may undermine academic work, delegitimize university in

Projection Bias and Youth’s and Parents’ Perceptions of Their Joint Political Discussions

This study investigated the idea that youth’s perceptions of the frequency of family political discussions and of parental political support mostly derive from their own political interest, a form of projection bias. Tests were performed of whether the same bias applies to parents, and whether youth’s and parents’ perceptions of political discussions and political support overlap to only a limited

The Alzheimer's Association international guidelines for handling of cerebrospinal fluid for routine clinical measurements of amyloid β and tau

The core cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarkers amyloid beta (Aβ42 and Aβ40), total tau, and phosphorylated tau, have been extensively clinically validated, with very high diagnostic performance for AD, including the early phases of the disease. However, between-center differences in pre-analytical procedures may contribute to variability in measurements across laboratories.

A combined measurement and modelling approach to assess the sustainability of whole-tree harvesting—a swedish case study

The demand of renewable energy has increased the interest in whole-tree harvesting. The sustainability of whole-tree harvesting after clear-cutting, from an acidification point of view, depends on two factors: the present acidification status and the further loss of buffering capacity at harvesting. The aims of this study were to investigate the relationship between these two factors at 26 sites a

Associations of prenatal methylmercury exposure and maternal polyunsaturated fatty acid status with neurodevelopmental outcomes at 7 years of age : results from the Seychelles Child Development Study Nutrition Cohort 2

BACKGROUND: Fish is a primary source of protein and n-3 PUFA but also contains methylmercury (MeHg), a naturally occurring neurotoxicant to which, at sufficient exposure levels, the developing fetal brain is particularly sensitive. OBJECTIVES: To examine the association between prenatal MeHg and maternal status of n-3 and n-6 PUFA with neurodevelopment, and to determine whether PUFA might modify p

Exogenous LL-37 but not homogenates of desquamated oral epithelial cells shows activity against Streptococcus mutans

Objective: The antimicrobial peptide hCAP18/LL-37 is detected in desquamated epithelial cells of human whole saliva, but the functional importance of this pool of hCAP18/LL-37 is not understood. Here, we assess the impact of homogenates of desquamated oral epithelial cells and exogenous, synthetic LL-37 on two oral bacteria: S. mutans and S. gordonii. Material and methods: Desquamated epithelial c

Rekindling the Agenda on Women, Peace and Security: can the EU lead by example?

The terrain of war and peace is not gender neutral. This was recognised for the first time by the UN Security Council in its resolution 1325 (UNSC 1325) adopted on 31 October 2000. It is a historic decision for the global efforts to achieve the equality of women and girls in this terrain. For the first time, the principal organ with primary responsibility for international security acknowledged a

Management of Spontaneous Isolated Mesenteric Artery Dissection : A Systematic Review

Background and Aims: There are increasing reports on case series on spontaneous isolated mesenteric artery dissection, that is, dissections of the superior mesenteric artery and celiac artery, mainly due to improved diagnostic capacity of high-resolution computed tomography angiography performed around the clock. A few case–control studies are now available, while randomized controlled trials are

Asymmetric contributions of seed and pollen to gene dispersal in the marsh orchid Dactylorhiza umbrosa in Asia Minor

Orchids differ from other plants in their extremely small and partly air-filled seeds that can be transported long distances by wind. Seed dispersal in orchids is expected to contribute strongly to overall gene flow, and orchids generally express low levels of genetic differentiation between populations and low pollen to seed flow ratios. However, studies in orchids distributed in northern Europe