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Several ligands based upon 2-substituted bicyclic[2.2.2]octane-2,6-diols (BODOLs) were synthesized and evaluated in two catalytic reactions: I) the Ti(IV)-mediated catecholborane asymmetric reduction of prochiral ketones and II) as catalysts in the asymmetric addition of diethylzinc to aromatic aldehydes. The ligands were prepared by baker's yeast mono-reduction of bicyclo[2.2.2]octane-2,6-dione,
Understanding consumer experiences of products is becoming increasingly important for producers acting on the global market. This paper presents a pilot study done as part of the development of a VIPET (Visual Internet Product Experience Tool), a future tool for remote user assessment of product experiences. The aim of the tool is to provide users with a convenient and intuitive approach to assess
Popular Abstract in Swedish Den främsta orsaken till att cancer kan leda till döden är att tumörceller växer in i angränsande vävnad (invasiv) och tar sig in i blodet eller lymfsystemet och på så sätt sprids (metastaserar) till andra ställen i kroppen och stör funktionen i livsviktiga organ dvs tumören får ett aggressivt växtsätt. Det är därför viktigt, både ur prognostisk och terapeutisk synvinkeThe progressive process of tumour invasion and generation of metastases is the primary cause of death for most patients with cancer. Some of the regulatory components of this progressive process are adhesion, migration, and proteolysis. Urokinase -type plasminogen activator (u-PA) is a serine protease associated with tissue remodelling, cellular invasiveness, matrix degradation, angiogenesis, and
Antologi med inledning plus fem artiklar om olika perspektiv på vad som utmärker samtidshistoria.
Different theories have changed the way we address to technol-ogy. In the debate on the core of Information System (IS), El Sawy identi-fied three faces of IS views: connection, immersion, and fusion. El Sawy contends that it may be time for a natural shift of emphasis from the con-nection view to the immersion view to the fusion view as IT continues to morph and augment its capabilities. In the f
The paper introduces a probabilistic semantics for the paraconsistent temporal logic Ab presented by the authors in a previous work on future contingents. Probabilistic concepts help framing two possible interpretations of the logic in question - a `subjective' and an `objective' one - and explaining the rationale behind both of them. We also sketch a proof-method for Ab and address some considera
Two enzymes involved in the biosynthesis of polyamines, ornithine decarboxylase (ODC, from human and Leishmania donovani) and spermidine synthase (SPDS, from Plasmodium falciparum and Caenorhabditis elegans) were studied using biochemical methods, homology modelling and X-ray crystallography. ODC catalyses the first and committed step in polyamine biosynthesis, the decarboxylation of ornithine to
Stability problems associated with haptics and robot control with obstacle avoidance are analyzed. Obstacle avoidance algorithms are revised to accomplish stable redesign using absolute stability and passivity theory. A modification of potential functions for haptic rendering and obstacle avoidance allowing stable operation for high stiffness is proposed. The modification leads to velocity-depende
Popular Abstract in Swedish Undersökningar om hur anhöriga till svårt psykiskt sjuka upplever sin situation är ovanliga i Sverige. Däremot har anhörigas situation oftare uppmärksammats i undersökningar i England och USA. Den moderna samhällsbaserade psykiatrin behöver kunskap om anhörigas situation både för att kunna bedriva en effektiv vård, för att möjliggöra ett optimalt deltagande i vården fråImportant aspects of family burden, participation in care and needs for support among a total of 422 relatives to severely mentally ill patients, voluntarily and compulsorily admitted to hospital, were investigated in a study performed between 1986-1997. The results showed high levels of both external and internal experienced burden among the relatives. The level of burden remained on an almost eq
INTRODUCTION Anaesthesia induced hypothermia is a common serious but preventable condition associated with increased bleeding and blood transfusion, increased risk for surgical site infections and increased risk for morbid cardiac events. Active warming is effective in preventing hypothermia but there is a need for more easy to use cost-effective products making active warming available to more pa
