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Railway Open System Tribology

Tribology in the railway system is of increasing interest in the new railway era due to the demand for higher speed and load capacity. Since railway vehicles operate in an open environment, their performance depends greatly on temperature, humidity and natural and artificial contaminants. Meanwhile, the “feedback” of railway vehicles to the surroundings, such as noise and airborne particles, is of

Hip arthroplasty for acute hip fracture in patients with neurological disorders : A report Of 9,702 cases from the Swedish arthroplasty register

Introduction: The purpose of this study was to investigate neurological disorder as a risk factor for dislocation following arthroplasty for acute hip fractures. We also analysed medical and surgical adverse events (AE), readmission, reoperation, revision, and mortality as secondary outcomes. Methods: A longitudinal cohort study using prospectively collected and aggregated data from the Swedish Hi

Shear strain and inflammation-induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction : A computational study

Excessive tissue deformation near cartilage lesions and acute inflammation within the knee joint after anterior cruciate ligament (ACL) rupture and reconstruction surgery accelerate the loss of fixed charge density (FCD) and subsequent cartilage tissue degeneration. Here, we show how biomechanical and biochemical degradation pathways can predict FCD loss using a patient-specific finite element mod

Bringing Advanced Therapies for Parkinson's Disease to the Clinic : An Analysis of Ethical Issues

Advanced therapies for Parkinson's disease (PD) constitute a broad range of treatments, each presenting specific ethical challenges. Some of these therapies are established and in clinical use, like device-aided therapies, and others, based on advanced therapeutic medicinal products (ATMPs), are still in early stage of clinical trials. This paper focuses on some common ethical issues arising in th

Human complex-forming glycoprotein, heterogeneous in charge : the primary structure around the cysteine residues and characterization of a disulfide bridge

The amino acid sequence of the cysteine-containing regions of human complex-forming glycoprotein, heterogeneous in charge (protein HC) was determined by studies of the tryptic peptides of the completely reduced and radioalkylated protein. One of the cysteines was located in the amino-terminal part of the molecule at position 34....Diagonal map electrophoresis showed that the cysteine residue in th

Studying the innate immune response to myocardial infarction in a highly efficient experimental animal model

The reduction in mortality following acute myocardial infarction (AMI) is an important achievement of modern medicine. Despite this progress, AMI remains the most common cause of heart failure (HF) and HF-related morbidity and mortality. The involvement of the innate immune response in different stages after AMI has attracted important attention in recent years. With the increasing range of potent

Does Engaging in Data Philanthropy Impact Business Value?

Data philanthropy (DP) is a new but much-lauded phenomenon. Extant DP research has been either conceptual, exploratory, and/or qualitative. The present study seeks to examine the business value of data philanthropy to the donor firm. We use an event study method to analyze stock performance of public firms associated with data philanthropy activities to determine if a link exists. We find signific

Comparison of Long-term Performance of Bioprosthetic Aortic Valves in Sweden from 2003 to 2018

Importance: The performance of bioprosthetic aortic valves is usually assessed in single valve models or head-to-head comparisons. National databases or registries offer the opportunity to investigate all available valve models in the population and allows for a comparative assessment of their performance. Objective: To analyze the long-term rates of reintervention, all-cause mortality, and heart

Timing of mechanical circulatory support during primary angioplasty in acute myocardial infarction and cardiogenic shock : Systematic review and meta-analysis

Objectives: We aim to define whether the timing of microaxial left ventricular assist device (IMLVAD) implantation might impact on mortality in acute myocardial infarction (AMI) cardiogenic shock (CS) patients who underwent primary percutaneous coronary intervention (PPCI). Background: Despite the widespread use of PPCI, mortality in patients with AMI and CS remains high. Mechanical circulatory su

Aquaporin-5 in breast cancer

The water channel aquaporin-5 (AQP5) is essential in transepithelial water transport in secretory glands. AQP5 is ectopically overexpressed in breast cancer, where expression is associated with lymph node metastasis and poor prognosis. Besides the role in water transport, AQP5 has been found to play a role in cancer metastasis, migration, and proliferation. AQP5 has also been shown to be involved

Perception of COVID-19 impacts on the construction industry over time

The emergence of COVID-19 has been changing in the world since 2020 and prompted social, cultural, and economic systems to adjust their structures, routines, and processes. The economic aspects of the pandemic appeared soon, and many industries changed their workflow and procedures through a mandatory or recommended quarantine. Knowing the impact of COVID-19 on different areas of construction proj

Evaluation of nonlinear static and dynamic analysis of steel braced frame buildings subjected to near-field earthquakes using FBD and DBD

Near-field earthquake is one of the primary sources of ground motions that significantly affecting the structure's seismic response in its surrounding area containing pulse-long periods. The two popular and reliable approaches for the seismic investigation of structures are known as the force and displacement-based seismic design (FBD and DBD), extensively developed in the literature. In the prese

Construction schedule, an influential factor on air pollution in urban infrastructure projects

Urbanization growth and aging infrastructures necessitate new infrastructure construction projects in congested urban areas. Urban construction projects interrupt the regular on-road vehicle traffic flow that affects air pollution concentration in the adjacent areas. The project schedule, however, is a possible contributor to the air pollution which has been neglected to date. This research propos

Air pollution concentration near sensitive urban locations : A missing factor to consider in the grade separation projects

The high vehicle congestion is the main contributing factor to air pollution originated from the engine's combustion in many urban areas. Grade separation projects have been used to solve this problem and have resulted in overall air pollution reduction in many cases. Many grade separation projects are constructed near sensitive urban locations accommodating susceptible individuals. This research

Approximation problems and weights

This thesis is mainly concerned with investigations of approximation problems on spaces of analytic functions on the unit disc in the complex plane, which naturally arise in connection to spectral problems of certain classes of linear operators acting on the spaces in question. For instance, quasi-nilpotency of certain analytic paraproducts on the Hardy spaces and on the Bergman spaces are investi

Pain management with popliteal block for fibular graft harvesting in head and neck reconstruction; a randomised double-blind placebo-controlled study

BACKGROUND AND OBJECTIVES: Curative treatment for locally advanced head and neck tumours often includes reconstructive surgery using a microvascular free flap. Effective recuperation is essential but may be impeded by postoperative donor site pain. The aim of this study was to evaluate the effects of a continuous popliteal block on postoperative pain after fibular graft harvesting.MATERIAL AND MET

Free-Standing Metal Halide Perovskite Nanowire Arrays with Blue-Green Heterostructures

Vertically aligned metal halide perovskite (MHP) nanowires are promising for various optoelectronic applications, which can be further enhanced by heterostructures. However, present methods to obtain free-standing vertically aligned MHP nanowire arrays and heterostructures lack the scalability needed for applications. We use a low-temperature solution process to prepare free-standing vertically al