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This study aimed to evaluate the permeation-enhancing properties of Coegin Pharma’s gel serum formulation on NPP-4, a peptide of interest for melanogenesis stimulation. A full-thickness reconstructed human skin model (MatTek EpiDermFT), comprising epidermis and dermis, was used to evaluate NPP-4 distribution in the gel serum vs a H2O reference vehicle. In parallel, methylene blue was used as a mod
