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Chemokine (C-C motif) receptor 2 (CCR2)-signaling can mediate accumulation of microglia at sites affected by neuroinflammation. CCR2 and its main ligand CCL2 (MCP-1) might also be involved in the altered metabolism of beta-amyloid (Aβ) underlying Alzheimer's disease (AD). We therefore measured the levels of CCL2 and three other CCR2 ligands, i.e. CCL11 (eotaxin), CCL13 (MCP-4) and CCL26 (eotaxin-3

We develop a general patch-use model of central place foraging, which subsumes and extends several previous models. The model produces a catalog of central place effects predicting how distance from a central place influences the costs and benefits of foraging, load-size, quitting harvest rates, and giving-up densities. In the model, we separate between costs that are load-size dependent, i.e. a d

In this thesis, computationally efficient statistical models for large spatial environmental data sets are constructed. In the first part of the thesis, a method for estimating spatially dependent temporal trends is developed. A space-varying regression model, where the regression coefficients for the spatial locations are dependent, is used. The spatial dependence structure is specified by a Ga

Participants decided whom of two patients to prioritize for surgery in three studies. The factual quantitative information about the patients (e.g., probability of surviving surgery) was given in vignette form with case descriptions on Visual Analogue Scales - VAS's. Differentiation and Consolidation theory predicts that not only the attractiveness of facts but also the mental representations of o

This article is about the cognitive meanings of animal ornamentation in a long term perspective. Special focus is upon the relation between the images of animal ornamentation and verbal expressions in the heroic skaldic poetry from the early medieval period. The article also discuss animal ornamentation in relation to gender.

This paper presents the results of combined investigation of the chemical bond formation in fluorinated multiwalled carbon nanotubes (MWCNTs) with different fluorine contents (10-55 wt %) and reference compounds (highly oriented pyrolytic graphite crystals and "white" graphite fluoride) using x-ray absorption and photoelectron spectroscopy at C 1s and F 1s thresholds. Measurements were performed a

Vertical arrays of direct band gap III-V semiconductor nanowires (NWs) hold the prospect of cheap and efficient next-generation photovoltaics, and guidelines for successful light-management are needed. Here, we use InP NWs as a model system and find, through electrodynamic modeling, general design principles for efficient absorption of sun light in nanowire arrays by systematically varying the nan

Many control engineering tasks nowadays rely on the simulation of complex multi-physics systems. Modern tools allow to build the required dynamic models conveniently, thanks to Object-Oriented Modelling languages, e.g., Modelica, and to perform simulations with hardly any additional effort on the part of the analyst. However, when simulation speed is of concern, the same tools fall short of exploi

Popular Abstract in Swedish Hjärt- och kärlsjukdomar är den främsta orsaken till en för tidig död för både män och kvinnor i dagens industrialiserade samhällen. I det akuta förloppet av dessa sjukdomar spelar blodplätten (trombocyten) en viktig roll då den är inblandad i bildandet av blodproppar. Den kärnlösa och kortlivade trombocytens roll är vanligen en annan och central i läkningsprosessen av Platelets are central for the primary haemostatis. The platelet has surface bound receptors that are vital for the platelet activation. One of these receptors, the purinergic ADP-activated G-protein coupled receptor (GPCR) P2Y12 is a key receptor for platelet activation, and thus for thrombus formation, which makes P2Y12 a target in pharmaceutical antiplatelet therapies. As a complement during rev

1/f noise is studied in dual-gated InAs nanowire transistors consisting of an omega top gate with high-k atomic layer deposited dielectric and silicon dioxide to substrate back gate. Noise spectra at varying gate bias combinations are compared from devices with differing top-gate lengths to separate the noise contributions of the top-gated channel from the ungated access portion, including the met

Popular Abstract in Swedish Rökning är den vanligaste och viktigaste riskfaktorn för att få sänkt lungfunktion. Kroniskt obstruktiv lungsjukdom (KOL) orsakas oftast av rökning, men drabbar inte alla som röker. Det är en sjukdom som ger försämrad lungfunktion och de som drabbas upplever andfåddhet och hosta, ibland med slemproduktion. För att ställa diagnosen KOL krävs att lungfunktionen har undersSmoking is the most common and important risk factor for reduced lung function. Chronic Obstructive Pulmonary Disease (COPD) affects mainly smokers and is characterized by airflow obstruction, assessed using one of two major diagnostic spirometric criteria. Aspects of lung function besides spirometry in smokers fulfilling none, either or both of the spirometric criteria for COPD are not well known

Background Increased levels of thyroglobulin (Tg) and thyroid-stimulating hormone (TSH) are associated with differentiated thyroid carcinoma (TC) risk, but strong epidemiological evidence is lacking. Methods Three hundred fifty-seven incident TC case patients (n = 300 women and 57 men; mean age at blood collection = 51.5 years) were identified in the EPIC cohort study and matched with 2 (women) or

Objectives To determine the effect of an ultrasound training course on the performance of pattern recognition when used by less experienced examiners and to compare the performance of pattern recognition, a logistic regression model and a scoring system to estimate the risk of malignancy between examiners with different levels of experience. Methods Using ultrasound images of selected adnexal mass

Background: There is a controversy regarding the existence of a socio-economic gradient for cerebral palsy. Perinatal emergencies and preterm birth increase the risk for the offspring to develop cerebral palsy. The aim of this study was to investigate the association of socio-economic indicators with cerebral palsy (CP) and the role of perinatal health as mediator of this association. Methods: Reg

This article about Federico Fellini’s Amarcord (1973) and Ingmar Bergman’s Fanny and Alexander (1982) concerns one aspect of the directors’ childhood memories, namely how authoritarian institutions are used to disrupt otherwise fairly idyllic and nostalgic lives and worlds. The films blend detailed memories with playful fantasies, combine experiences of the directors’ alter ego Titta and Alexander

In this paper a data set of 716 radiocarbon dates from the South-Swedish Upland is presented. The dated material is charcoal found beneath clearance cairns, which originates from agricultural land clearance by fire. The chronological distribution of the calibrated dates, presented as summed probability, is interpreted in terms of agricultural fluctuations as well as long-term changes in human popu

We studied the heating efficiency of an electrically heated vest (EHV), its relationship to the microclimate temperature distribution in a three-layer clothing ensemble and the effect of an EHV on the clothing’s total thermal insulation by both theoretical analysis and thermal manikin measurements. The heat losses at different ambient conditions and heating states were recorded and the heating eff