The study concerns whether DNA flow cytometry and estrogen receptor analysis might help predict which breast cancer patients, particularly node-positive ones, were at the greatest risk of developing loco-regional recurrence (LRR). Such patients would best benefit from postoperative radiotherapy following modified radical mastectomy and axillary lymph node dissection. After this type of surgery, 50

We revised the hip (6 stems and 5 sockets) with impacted morselized allografts and cement in 6 patients. We followed prosthetic migration by roentgen radiostereometric analysis (RSA) every 7th day for 6 weeks after the first (index) examination performed on the first postoperative day before mobilization. Most of the migration occurred during the first 2 weeks. In most cases more than half of the

This paper describes the development of two web based education and training packages EMERALD and EMIT designed to meet the training needs of professional medical physicists. The programme has been developed over a number of years by collaboration between hospitals and universities across Europe. The programme concentrates on assisting competence development in five initial areas; diagnostic radio

Biosensors based on whole bacterial cells and on bacterial heavy metal binding protein were used to determine the mercury concentration in soil. The soil samples were collected in a vegetable garden accidentally contaminated with elemental mercury 25 years earlier. Bioavailable mercury was measured using different sensors: a protein-based biosensor, a whole bacterial cell based biosensor, and a pl

Genetic engineering has been used to construct fusion proteins of Fusarium solani pisi cutinase and tryptophan-based tags, expressed in Saccharomyces cerevisiae, to increase the partitioning in aqueous two-phase systems. The separation systems were composed of thermoseparating polymers (random copolymers of ethylene oxide and propylene oxide, EOPO) and detergents (C12EOn). In this study, the fluor

We take our own life stories as points of departure to look at some of the ways in which women were politicized in Argentina and West Germany (our respective countries of origin), focusing on similarities as well as differences in our politicization processes. We aim at putting present discussions about global political movements into a historical perspective. We want also to illuminate the centra

A model of how to calculate the load distribution for a chain drive is presented. In the model the complete standard geometry is used without any assumptions. The rollers which are in contact with the sprockets can move freely along the tooth flanks and their positions are given be force equilibrium. Since the positions of the rollers and thereby also the load distribution are dependent on the two

Popular Abstract in Swedish Wellpapp är ett populärt material i förpackningar för transport och lagring av konsumentvaror. Den viktigaste anledningen till dess popularitet är materialets höga styvhet och styrka, i förhållande till vikt och kostnad. Ingenjörsmässig användning av wellpapp kompliceras av många faktorer. En väsentlig nackdel är materialets känslighet för fuktpåverkan, vilken dessutom The storage of compressive loaded boxes in an environment with naturally varying humidity is a practical issue in corrugated board employment. Time dependent variables such as moisture content, strain fields, stress fields and material strength play important roles for the time to failure. Supplementary, the stochastic nature of material and moisture load is obstructing the prediction of a reliabl

A series of placebo powders for inhalation was characterized regarding bulk density and powder flowability using different techniques. The powders were of the ordered mixture type and were prepared by mixing a pharmaceutical carrier grade of lactose with different fractions of intermediate sized and fine (i.e., micronized) lactose. A modified Hausner Ratio was obtained by measurement of the poured

We used site-directed mutagenesis to alter the specificity of human cystatin C, an inhibitor with a broad reactivity against cysteine proteinases. Nine cystatin C variants containing amino acid substitutions in the N-terminal (L9W, V10W, V10F and V10R) and/or the C-terminal (W106G) enzyme-binding regions were designed and produced in Escherichia coli. It was discovered that the inhibition profile

The mol-ecule of the title compound, C14H14S, lies on a crystallographic twofold axis running through the central S atom, and hence mol-ecules have exact C-2 mol-ecular symmetry. Density-functional theory calculations reveal that the energy-optimized mol-ecular structure in the gas phase is close to that observed in the crystal structure. The crystal packing is dominated by double chains running a

BACKGROUND: Hereditary non-polyposis colorectal cancer (HNPCC) (Lynch cancer family syndrome I (LCFS1) and II (LCFS2)) is one of the most common hereditary cancer disorders. HNPCC results from dominantly inherited germline mutations in mismatch repair (MMR) genes, leading to genomic instability and cancer. No predictive physical signs of HNPCC are available to date. AIMS: Increased complexity in t

The kinetics of oxidation of hydroxylamine by iron() have been studied spectrophotometrically. The effects of pH, reactant and product concentrations led to two experimental rate expressions. The results obtained are consistent with a mechanism dependent on the relative iron(III)-to-hydroxylamine concentrations; an excess of iron() gives a stoichiometry of 2 : 1 for the total reaction and N2O as t