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Time-resolved white light transillumination for optical imaging

Purpose: To describe a new breast-imaging method with the potential of multi-spectral optical transillumination based on a time-resolved technique. Material and Methods: A breast phantom was irradiated with ultra-short laser pulses of white light generated by self-phase modulation of an incident high-power laser pulse in water. Time-resolved detection of the transmitted light was performed. Contra

Gene-Lifestyle Interactions in Complex Diseases: Design and Description of the GLACIER and VIKING Studies.

Most complex diseases have well-established genetic and non-genetic risk factors. In some instances, these risk factors are likely to interact, whereby their joint effects convey a level of risk that is either significantly more or less than the sum of these risks. Characterizing these gene-environment interactions may help elucidate the biology of complex diseases, as well as to guide strategies

Characterization of an alternative transcript of the human CREB3L2 gene.

CREB3L2, a member of the CREB3 family of transcription factors, spans >120 kbp and is composed of 12 exons. We characterized a widely expressed transcript of CREB3L2 generated by an intronic polyadenylation site in intron 4 of the gene. It could be translated to a CREB3L2 variant which is localized both in the nucleus and the endoplasmatic reticulum. The protein retains the N-terminal transactivat

Att återförtrolla det sekulariserade samhället: Är Sverige på väg in i Vattumannens tidsålder?

Artikeln diskuterar en nyandlig terapiform och en kurs i personalutveckling för att exemplifiera hur dessa och liknande rörelser försöker med nya medel hitta och har hittat vägar in i samhällets institutioner. De vill med nya, ”vetenskapliga” rön medvetandegöra svenskarna om deras inre potential och de vänder sig inte bara till individuella sökare utan erbjuder också sina tjänster till offentliga

The accuracy of absorbed dose estimates in tumours determined by Quantitative SPECT: A Monte Carlo study.

Abstract Background. Dosimetry in radionuclide therapy estimates delivered absorbed doses to tumours and ensures that absorbed dose levels to normal organs are below tolerance levels. One procedure is to determine time-activity curves in volumes-of-interests from which the absorbed dose is estimated using SPECT with appropriate corrections for attenuation, scatter and collimator response. From cor

General intellectual capacity of young men with cleft lip with or without cleft palate and cleft palate alone.

We report on the general intellectual capacity of men around 17-19 years of age and with cleft lip either with or without cleft palate (CLP) or cleft palate alone. Data were obtained from the Swedish National Service enrolment register for the years 1991-1997, about 335 individuals with CLP and 88 with cleft palate alone, who were compared with a control group consisting of 272 879 people. Those w

The botanical integrity of wheat products influences the gastric distention and satiety in healthy subjects.

BACKGROUND: Maintenance of the botanical integrity of cereal kernels and the addition of acetic acid (as vinegar) in the product or meal has been shown to lower the postprandial blood glucose and insulin response and to increase satiety. However, the mechanism behind the benefits of acetic acid on blood glucose and satiety is not clear. We hypothesized that the gastric emptying rate could be invol

Development and quality analysis of the Work Experience Measurement Scale (WEMS).

Instruments related to work are commonly illuminated from an ill-health perspective. The need for a concise and useable instrument in workplace health promotion governed the aim of this paper which is to present the development process and quality assessment of the Work Experience Measurement Scale (WEMS). A survey, using a questionnaire based on established theories regarding work and health, and

Profiling genetic variation along the androgen biosynthesis and metabolism pathways implicates several single nucleotide polymorphisms and their combinations as prostate cancer risk factors.

Several candidate genes along androgen pathway have been suggested to affect prostate cancer risk but no single gene seems to be overwhelmingly important for a large fraction of the patients. In this study, we first screened for variants in candidate genes and then chose to explore the association between 18 variants and prostate cancer risk by genotyping DNA samples from unselected (n = 847) and