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CONTEXT/OBJECTIVE: The aim of this study was to examine the effect of statins and other lipid-lowering agents on the development of Graves orbitopathy (GO) in patients with newly diagnosed Graves disease (GD). METHODS: Our sample included the full adult population of individuals living in Sweden with newly diagnosed GD between 2005 and 2018 (n = 34 894). We compared the GO incidence in statin user
The elliptic flow of electrons from beauty hadron decays at midrapidity (|y|
A pre-requisite for the design of wireless systems is the understanding of the propagation channel. While a wealth of propagation knowledge exists for bands below 6 GHz, the same can not be said for bands approaching millimeter-wave frequencies. In this paper, we present the design, implementation and measurement-based verification of a re-configurable 27.5-29.5 GHz channel sounder for measuring d
Vegetation phenology obtained from time series of remote sensing data is relevant for a range of ecological applications. The freely available Sentinel-2 imagery at a 10 m spatial resolution with a ~ 5-day repeat cycle provides an opportunity to map vegetation phenology at an unprecedented fine spatial scale. To facilitate the production of a Europe-wide Copernicus Land Monitoring Sentinel-2 based
Young adults experiencing mental health problems are less educated than their peers, putting them in a more vulnerable position for employment and career possibilities. While Supported employment models have been widely implemented, educational supports may be necessary in order to contribute to longer term and sustainable employment. The aim of this study was to describe the state of current rese
Introduction: The role of chemotherapy for patients with dedifferentiated chondrosarcoma (DDCS) is still under discussion. Here, we present the outcome in patients with DDCS treated with intensive chemotherapy from the EUROpean Bone Over 40 Sarcoma Study. Materials and methods: The chemotherapy regimen included doxorubicin, ifosfamide and cisplatin. Postoperative methotrexate was added in case of
This paper looks into the system of student informants (xuesheng xinxiyuan), which is, to systematically recruit and more generally, to mobilise or encourage the students to watch and inform on their professors on university campuses in China. After Xi Jinping assumed power in late 2012, along with the Chinese Communist Party’s intensifying control of university space, mounting reports show that p
Excessive bleeding is a serious complication associated with impaired survival after surgery for acute type A aortic dissection (ATAAD). Different ABO blood groups are associated with variable levels of circulating von Willebrand factor and therefore potentially altered risks of surgical haemorrhage. The current study aimed to assess the impact of blood group on bleeding complications after ATAAD
Along with China’s long-delayed response to the COVID-19 outbreak is its nationwide activation of the ‘gridded management’ system. Relying largely on the mass recruitment of the war-time rhetoric and ideology in mobilizing the people to watch and tell on each other, this ‘gridded management’ system is officially highlighted as playing a key role in China’s combat against COVID-19. Through examinin
The cutback was widely used in advanced gas turbines to protect the trailing edge. The land was a main structure in the cutback region. Therefore, the present study describes a numerical investigation on the film cooling performance in the cutback region with various land shapes (straight- expanding land, arch- expanding land, contracting- expanding land and campaniform land) and blowing ratios (0
Herwig 7 is a general-purpose Monte Carlo generator of particle collisions comprising both hard perturbative as well as soft phenomenological physics. Herwig is therefore capable to describe the entire final state of hadronized particles in a collision event. A spacetime topology of a parton system entering hadronization is fully described and tested for the first time. A combination of informatio
The correlation function measured in ultrarelativistic nuclear collisions is strongly non-Gaussian. Using two different models we study which effects can influence its shape and how much. In particular, we focus on the parametrizations expressed with the help of Lévy-stable distributions. We show that the Lévy index may deviate substantially from 2 due to non-critical effects such as resonance dec
The Learning with Errors (LWE) problem receives much attention in cryptography, mainly due to its fundamental significance in post-quantum cryptography. Among its solving algorithms, the Blum-Kalai-Wasserman (BKW) algorithm, originally proposed for solving the Learning Parity with Noise (LPN) problem, performs well, especially for certain parameter settings with cryptographic importance. The BKW a
Male butterflies in the hyperdiverse tribe Eumaeini possess an unusually complex and diverse repertoire of secondary sexual characteristics involved in pheromone production and dissemination. Maintaining multiple sexually selected traits is likely to be metabolically costly, potentially resulting in trade-offs in the evolution of male signals. However, a phylogenetic framework to test hypotheses r
The Genomic Medicine Sweden (GMS) initiative aims to strengthen precision medicine across the country. This will be accomplished through the implementation of large-scale sequencing techniques in Swedish healthcare. With a patient-centered view, initial efforts will focus on rare diseases, cancer, pharmacogenomics, and infectious diseases, and subsequently extend to complex diseases. GMS is being
Since the demand for raw material is still growing, historical mining dumps are in the focus of geophysical investigations because they can still bear valuable minerals. Moreover, the risk assessment of groundwater contamination due to solutions processes within slag dumps is an important part of dump characterisations. One suitable technique to use is the spectral induced polarisation (SIP) metho
Spectral information from induced polarisation (IP) measurements can be used for several applications as the characterisation of the lithology, the estimation of hydraulic parameters, the localization of contaminated areas and many more.So far, the spectral content has been mainly determined in frequency domain (FD). Due to significant instrumental developments and advanced data processing and inv
BACKGROUND: Emerging data support the use of thymidine kinase 1 (TK1) activity as a prognostic marker and for monitoring of response in breast cancer (BC). The long-term prognostic value of TK1 kinetics during neoadjuvant chemotherapy is unclear, which this study aimed to elucidate. METHODS: Material from patients enrolled to the single-arm prospective PROMIX trial of neoadjuvant epirubicin, docet
