Genome-wide association studies have shown that variation in MTNR1B (melatonin receptor 1B) is associated with insulin and glucose concentrations. Here we show that the risk genotype of this SNP predicts future type 2 diabetes (T2D) in two large prospective studies. Specifically, the risk genotype was associated with impairment of early insulin response to both oral and intravenous glucose and wit

Popular Abstract in Swedish I och med de smarta mobiltelefonernas framväxt överförs allt mer data i de mobila nätverken. Detta ställer allt högre krav på mobilsystemen och de mobila enheterna. Ett effektivt utnyttjande av de tillgängliga resurserna är nödvändigt. Det tillgängliga frekvensspektrat är begränsat och måste utnyttjas så väl som möjligt. Detta görs bland annat genom att öka mängden dataIn this thesis different aspects of baseband implementation of mobile communication systems is treated. The content is focused on symbol detection and channel estimation in MIMO and OFDM. The thesis deals with the complete chain from algorithm to silicon implementation within these areas. The main contribution of this thesis is described in the included papers. The first paper handles symbol dete

In this study we investigated how mood influences the degree of realism in participants’ confidence judgments (based on an episodic memory task). Using music and film in combination, we successfully induced half of the participants into an elated mood, but failed to induce a sad mood in the other half. Contrary to our prediction, our data indicated that there was no difference in the realism of th

Aims: To illuminate patients' experiences of being cared for and nurses' experiences of caring for patients in a multiple-bed hospital room. Background: Many patients and healthcare personnel seem to prefer single-bed hospital rooms. However, certain advantages of multiple-bed hospital rooms (MBRs) have also been described. Method: Eight men and eight women being cared for in a multiple-bedroom

Clinical studies have shown that moderately intense physical activity effectively treats various types of depression. Beneficial effects have been reported in the acute phase of the disease as well as in a long-term perspective. In addition, epidemiological studies have shown that inactivity increases the risk of depression and that exercise prevents relapse. Depressed patients are often prescribe

In patients undergoing peritoneal dialysis (PD) for end-stage renal failure, the optimum electrolyte composition of a dialysis solution is that which best serves the homeostatic needs of the body. Comparing the transperitoneal removal of electrolytes by conventional PD solutions (CPDSs) with that by normal kidneys, it is evident that peritoneal removal is in the lower range of what can be consider

The objective was to study obesity and insulin resistance in relation to leisure time physical activity (LTPA) and occupational physical activity (OPA) in a Swedish population, with particular focus on sex differences. Using a cross-sectional design, waist circumference, body mass index (BMI), glucose/insulin metabolism, blood pressure, heart rate, self-reported education, smoking, alcohol consump

I Sverige inleddes utvecklingen mot entreprenaddriven äldreomsorg i början av 1990-talet. Sedan dess har antalet äldre som får hjälp av privata utförare blivit allt fler. Fortfarande är det dock en mindre andel av äldreomsorgen som drivs på entreprenad. Entreprenaddriften är en förhållandevis ny företeelse som fått stor massmedial uppmärksamhet genom åren. De effekter som hittills har kunnat pres

The second of two reports from the conference Virtual City in Lund, Sweden, in 1998.

In a previous study from our laboratory, high tumor levels of tissue inhibitor of metalloproteinases-1 (TIMP-1) have been associated with an adverse response to chemotherapy in metastatic breast cancer suggesting that TIMP-1, which is known to inhibit apoptosis, may be a new predictive marker in this disease. The purpose of this study was to investigate the association between TIMP-1 and objective