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Depth-profiling the composition of bimetallic nanoparticles using medium energy ion scattering

The near monolayer depth resolution of medium energy ion scattering is utilized to develop a probe of the depth dependent composition of bimetallic nanoparticles supported on planar oxide supports. The approach fits spectra of scattered ion intensity versus ion energy at well-defined scattering angles taking into account the asymmetric line shape in such spectra and also the depth dependent loss p

The European general practice research network presents the translations of its comprehensive definition of multimorbidity in family medicine in ten European languages.

Multimorbidity, according to the World Health Organization, exists when there are two or more chronic conditions in one patient. This definition seems inaccurate for the holistic approach to Family Medicine (FM) and long-term care. To avoid this pitfall the European General Practitioners Research Network (EGPRN) designed a comprehensive definition of multimorbidity using a systematic literature re

The Petersburg Text of Russian Cinema in Perestroika and Post-Perestroika Eras

In order to examine contemporary Russian cinema, this thesis has two points of departure: firstly the Petersburg myth, which is here defined as reversible or ambiguous since it includes both an eschatological and a cosmogonic aspect; and secondly, the Petersburg literary text as defined in works by Vladimir Toporov. During the twentieth century, the vitality and actuality of the Petersburg myth wa

Novel aspects of the molecular mechanisms controlling insulin secretion

Pancreatic beta-cells secrete insulin by Ca2+-dependent exocytosis of secretory granules. beta-cell exocytosis involves SNARE (soluble NSF-attachment protein receptor) proteins similar to those controlling neurotransmitter release and depends on the close association of L-type Ca2+ channels and granules. In most cases, the secretory granules fuse individually but there is ultrastructural and bioph

Hypermodernist Travellers in a Postmodern World

Postmodernist perspectives in research have tended to embrace ambiguity, complexity, interconnectedness and contradiction, and have sometimes been described as a rejection of the ‘Grand Theories’ of Modernism. They have been said to reflect a view that previously taken-for-granted assumptions about the organizing principles of social phenomena must be regarded sceptically, and often make use of ir

DNA-lipid self-assembly: phase behavior and phase structures of a DNA-surfactant complex mixed with lecithin and water

The co-assembly of DNA and lipids has broad implications, from the structure of the cell nucleus to gene delivery formulations. To progress in the fundamental understanding of DNA-lipid interactions the self-assembly behavior of a cationic surfactant (dodecyltrimethylammonium, DTA) with DNA as a counterion in mixtures of water and lecithin was investigated. The phase diagram was established and th

The unknown but well-known wells in Holma. Public participation and norms in the City Tunnel Project in Malmö

Environmental management in the City Tunnel Project was a three-year, sociology of law research project (1999-2003) on how the new Environmental Code was applied to one of the largest infrastructural projects in Sweden: the City Tunnel in Malmö. The aim of this article is, after some years, to reflect on and re-examine what happened during the two extended consultations processes to try to find an

Apoptosis-Like Death in Bacteria Induced by HAMLET, a Human Milk Lipid-Protein Complex

Background: Apoptosis is the primary means for eliminating unwanted cells in multicellular organisms in order to preserve tissue homeostasis and function. It is characterized by distinct changes in the morphology of the dying cell that are orchestrated by a series of discrete biochemical events. Although there is evidence of primitive forms of programmed cell death also in prokaryotes, no informat

På väg mot integrerad vattenmiljöförvaltning–möjligheter och hinder på den lokala förvaltningsnivån.

On the background of geographical and structural barriers for integrated water management discussed by Castensson et al (1990) and Hägerstrand (1993) a case study in Kävlinge river catchment area in southern Scania, Sweden was conducted. The study focused on existing water-related and other forms of co-operation within and between municipalities. Obstacles for effective water management were studi

Structure and properties of the 5.5 K antiferromagnet EuAu2Ge2

A well crystallized sample of EuAti(2)Ge(2) was synthesized by arc-melting of the elements. The structure was refined on the basis of single crystal X-ray diffractometer data: ThCr2Si2 type, 14/mmm, a = 447.3(1), c = 1034.0(4) pm, wR2 = 0.0575, 148 F-2 values and 9 variables. The gold atoms have tetrahedral germanium coordination (261 pm Au-Ge). These AuGe4/4 tetrahedra share four common edges, le

Spatial variability of soil fungal and bacterial abundance: Consequences for carbon turnover along a transition from a forested to clear-cut site

Predicted alterations in belowground plant-allocated C as a result of environmental change may cause compositional shifts in soil microbial communities, and it has been hypothesized that such alterations will influence C mitigation in forest ecosystems. In order to investigate to what degree living trees influence the abundance and activity of mycorrhizal fungi, saprotrophic fungi, and bacteria we

Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.

Similar to other malignancies, urothelial carcinoma (UC) is characterized by specific recurrent chromosomal aberrations and gene mutations. However, the interconnection between specific genomic alterations, and how patterns of chromosomal alterations adhere to different molecular subgroups of UC, is less clear. We applied tiling resolution array CGH to 146 cases of UC and identified a number of re

Female urinary incontinence. A study on heredity, urodynamic and hormonal factors and the evaluation of a novel surgical technique

Popular Abstract in Swedish Ofrivilligt urinläckage, urininkontinens, omfattar mer än 50 miljoner människor i världen, varav cirka 500 000 i Sverige. Av dessa beräknas 2/3 vara kvinnor. Ofrivilligt urinläckage är ett medicinskt och socialt handikapp för den drabbade, operation och hjälpmedel förorsakar samhället stora kostnader. Risken för urininkontinens ökar med stigande ålder. I svenska studierAbstract Pelvic floor disorders (PFD) represent a major public health issue worldwide. Aims of this work Study I: to investigate associations between preoperative resting urethral parameters (MUCP, FL and CA) and objective outcome of laparoscopic colposuspension and, if possible, to identify cutoff values useful in clinical practice. Study II: to investigate a group of perimenopausal women reporti

Hip Fractures - Functional assessments and factors influencing in-hospital outcome of patients with hip fracture, a physiotherapeutic perspective

A hip fracture is probably one of the most fatal fractures for the elderly and estimated worldwide to reach 5 million cases annually by the year 2050. Thus, continuing efforts in preventing fractures, with more research and improved treatment strategies for those who do fracture, seem crucial. The primary aims of this thesis, which comprises seven original papers, including a total of 656 patients

Modelling procedures and properties of rubber in rolling contact

Rubber covered cylinders in rolling contact are studied in two cases; rolling over a flat surface and rolling over a groove. In the first case, two different finite element procedures are compared for the purpose of investigating if computational savings can be made when taking amplitude dependent effects into account by using a modified viscoelastic steady state rolling procedure. This procedure

Transcriptional Regulation of HIF2A/EPAS1 in Neuroblastoma

Popular Abstract in Swedish Cancer är den vanligaste dödsorsaken bland barn mellan 1–14 år i Sverige. Neuroblastom, som nästan uteslutande drabbar barn, är en aggressiv cancersjukdom som har sitt ursprung i det sympatiska (icke-viljestyrda) nervsystemet. I frisk vävnad råder strikt balans mellan celldelning och celldöd, medan cancerceller kännetecknas av en ohämmad celldelning och minskad celldödNeuroblastoma is a childhood tumor of the developing sympathetic nervous system (SNS) and is the most commonly diagnosed form of cancer in children before one year of age. Although survival curves have improved for these patients during the past decades, the conventional regimen of neuroblastoma treatment has clearly reached a plateau of efficiency with regard to increasing the survival rates of h