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Buildings of all types are increasingly becoming complex ‘systems of systems.’ They are subject to evolving societal objectives, new and innovative materials, and in many countries, regulatory ecosystems are having difficulty keeping pace with rapidly changing societal, environmental and technological changes. Two evolving objectives that are stimulating changes to buildings and communities are th
BACKGROUND: Diarrhea is a leading cause of death among children <5 years of age and can have long-term adverse consequences for human development. The World Health Organization has recommended the therapeutic use of zinc for the treatment of diarrhea, along with oral rehydration solutions, since 2004. We studied recent trends in the use of zinc to treat diarrhea in 23 low- and middle-income countr
Synchronizing free-electron laser pulses for time-resolved experiments is necessary as an unsynchronized system reduces the effective repetition rate of the experiment. Additionally, free-electron laser longitudinal coherence and spectral brightness are limited by electron beam energy spread. In this paper, a variable bunch compressor design and compression schemes were developed to: reduce klystr
This paper examines the origins of formal education in colonial Zambia and its long-term consequences for educational attainment and gender inequality. Combining novel panel data on the location of missionary stations and mission school enrolment by gender and missionary society from 1924 to 1953 with contemporary data from the 1990 Zambian census, we ana-lyze the long-term effects of missionary e
Ecosystems worldwide are experiencing a range of natural and anthropogenic disturbances, many of which are intensifying as global change accelerates. Ecological responses to those disturbances are determined by both the vulnerabilities of species and their interspecific interactions. Understanding how individual species contribute to the (in-)stability of an aggregated community property, or funct
Featured Application: Evaluating the effect of train impact velocity, pedestrian position, and station environment on head injury and run-over risk. Application to future safety device design. Introduction: Subway–pedestrian collisions are a significant and growing problem, but they are poorly understood. This study presents the first subway–pedestrian collision model with the aim of evaluating th
En vetenskapligt uppdaterad översikt av industriella revolutionen, med fokus på de inledande faserna i Storbritannien
The tumour microenvironment is programmed by cancer cells and substantially influences anti-tumour immune responses1,2. Within the tumour microenvironment, CD8+ T cells undergo full effector differentiation and acquire cytotoxic anti-tumour functions in specialized niches3–7. Although interactions with type 1 conventional dendritic cells have been implicated in this process3–5,8–10, the underlying
Introduction Delayed palliative management (DPM) is an alternative for prostate cancer (PCa) patients with poor performance status, or those who received radical treatment but progressed and no longer meet the criteria for curative treatment. PIONEER is a large network of federated data analytic platforms in PCa that aims to improve its care through the application of big data analytics. The objec
Horizontal gene transfer is one of the most important drivers of bacterial evolution. Transformation by uptake of extracellular DNA is traditionally not considered to be an effective mode of gene acquisition, simply because extracellular DNA is degraded in a matter of days when it is suspended in e.g. seawater. Recently the age span of stored DNA was increased to at least 2 Ma. Here, we show that
This article explores the representation of the female image in the visual artwork of generative AI and the gender issues in it, using eight different generative AI systems, ERNIE-ViLG 2.0, Shuhua, and Yihui from China and Nightcafe, Fotor, Jasper Art, DALLE and Deep dream generator from the West, as comparative cases. In this paper, female cyborg is selected as a representative of female images,
BACKGROUND Advanced Therapy Medicinal Products (ATMPs) for human use have advanced globally with the rapid adoption of Chimeric Antigen Receptor T-cell (CAR-T) therapies in haemato-oncology. CAR-T cell therapy and ATMPs have unique, significant acute and chronic toxicities, and appropriate patient care is crucial. Significant challenges, including the need for nurse education and training, accompa
Background: Stroke is one of the major chronic non-communicable diseases (NCDs) with high morbidity, disability and mortality. The key to preventing stroke lies in controlling risk factors. However, screening risk factors and quantifying stroke risk levels remain challenging. Methods: A novel prediction model for stroke risk based on two-level feature selection and deep fusion network (SRPNet) is
Women have made substantial gains in education in recent decades and outperformmen in educational attainment across the OECD, but the consequences of this reversal of the gender gap in education (RGE) have not been well researched. In this study, we address the association between the RGE and partnering, employment, and support for a right-wing populist party in Sweden. Of note, we explore the dif
Women have made substantial gains in education and outperform men regarding educational attainment across the OECD, but the consequences of this reversal of the gender gap in education (RGE) have not been well researched. We address the association between the RGE and partnering, employment, and support for a right-wing populist party in Sweden. We explore the differential impacts of women's educa
Politiska ledningar runtom i Europa måste agera bestämt när något land helt eller delvis försöker dra sig undan finansieringen av kollektiva varor, skriver Jerker Holm, professor vid ekonomihögskolan, Lunds universitet.
Abstract:Background:Chronic postoperative inguinal pain (CPIP) affecting daily activities is reported in 8-12% and moresevere pain between 0.6-6% after inguinal hernia repair. CPIP incidences are based on a variety ofPROMs and definitions of pain, making comparison between studies difficult. Pain during sexualactivity (SEX-P) is rarely studied in randomized settings. Few RCTs with large cohorts re
