Dysfunction of the gastrointestinal tract has now been recognized to affect all stages of Parkinson's disease (PD). The consequences lead to problems with absorption of oral medication, erratic treatment response, as well as silent aspiration, which is one of the key risk factors in developing pneumonia. The issue is further complicated by other gut abnormalities, such as small intestinal bacteria

BackgroundDense Non Aqueous Phase Liquids (DNAPL) such as chlorinated solvents are common pollutants stemming from different types of industries including dry cleaning facilities, and reports on cases showing serious risk to soil and ground water are frequent on a global scale. DNAPLs are especially problematic as they are denser than water and move down through the groundwater, not always followi

Background: Media frequently report on overall work-place challenges in Swedish schools, including teachers’ working conditions, their well-being, and students’ declining results. Language is the key to success in every school subject. Therefore, optimal language learning environments are important. Poor sound environments affect teachers’ vocal health, their general well-being, and students’ perf

Edward Joseph Snowden blev världsberömd när han visselblåste om USA:s statliga övervakningsprogram. Amnesty International kallade honom en hjälte som främjade mänskliga rättigheter och tvingade fram en viktig global debatt om massövervakning. Som en kontrast till detta skrev den faste skribenten i The New Yorker, Jeffrey Toobin, att Snowden är ”en grandios narcissist som förtjänar att sitta i fäng

Insulin stimulates Na+,K+-ATPase activity and induces translocation of Na+,K+-ATPase molecules to the plasma membrane in skeletal muscle. We determined the molecular mechanism by which insulin regulates Na+,K+-ATPase in differentiated primary human skeletal muscle cells (HSMCs). Insulin action on Na +,K+-ATPase was dependent on ERK1/2 in HSMCs. Sequence analysis of Na+,K+-ATPase α-subunits reveale

Type 2 (non-insulin-dependent) diabetes mellitus is a progressive metabolic disorder arising from genetic and environmental factors that impair beta cell function and insulin action in peripheral tissues. We identified reduced diacylglycerol kinase δ (DGKδ) expression and DGK activity in skeletal muscle from type 2 diabetic patients. In diabetic animals, reduced DGKδ protein and DGK kinase activit

In March 2018, it became publically known that Indian Space Research Organisation ISRO's launch on 12 January 2018 deployed four space objects into orbit that were not authorised by the Federal Communications Commission (FCC) of the United States of America (US). Prior to the launch with ISRO's Polar Satellite Launch Vehicle, US-based tech start-up Swarm Technologies had received a dismissal by th

Hydroacoustic and optical remote sensing have been commonly used to map shallow nearshore benthic features. However, the number, type, scale, and accuracy of the mapping products that can be obtained from the two sensors differ; as such, there can be limited agreement between their mapping products. These differences can be further accentuated if the hydroacoustic data are interpolated to produce

Människans reflektioner över etiska frågeställningar befinner sig i spänningen mellan att formulera vad som är allmänmänskligt och vad som kan betraktas som särskiljande för olika individer och grupper av människor. Hur ska vi leva tillsammans? Och vad är ett gott samhälle? Det som ska vara gemensamt och gränserna för olikhet måste (åter)erövras i varje tid. Och i varje tid samsas ”eviga” etiska s