Salinomycin attackerar cancerstamceller i hypoxi Bröstcancer är den näst vanligaste typen av cancer i Sverige och representerar cirka 15 % av alla cancerfall, med mer än 7500 nya fall årligen. Ett stort problem, som forskningen och sjukvården kämpar med, är tumörer som sprids och som återkommer efter några år. Den orsakande faktorn bakom dessa problem tros vara en liten mängd resistenta cancerce

Abstract European blackberries constitute a polyploid complex of closely related microspecies, which includes species in Rubus sect. Rubus and Rubus sect. Corylifolii of Rubus subgenus Rubus. These species reproduce by facultative agamospermy. New microspecies evolve from time to time by hybridization between Rubus sect. Rubus and R. caesius or R. idaeus, or by sexual reproduction. Because of the

Effekter på mossammansättning vid avverkningar i tallskog i södra Sverige Andelen skyddad skog är idag låg och för att ta reda på hur arter och mångfald kan bevaras måste produktionsskog studeras. Bottenskiktet i form av t.ex. mossor har stor betydelse för förekomst av andra artgrupper och även kommersiellt vid skogsföryngring. Sedan tidigare finns studier på långtidseffekter av kalavverkning meIn this study bryophyte species richness, abundance and sexual reproduction was screened in sampling plots in a planted costal Scots pine forest set in a logging system in Southern Sweden, with control plots in the adjacent nature reserve. Data was collected from seven different stands, with equal stand structures in a chronosequence after commercial thinning; data was in the same way collected fr

The information contained in the DNA (Deoxyribonucleic acid) of an organism that will finally be expressed, is first converted into a molecule called RNA (Ribonucleic acid). This is mainly composed of two types of sequences: the exons, carrying the information that will give rise to the formation of proteins and will be finally expressed in the organism, and the introns, which mainly include regul

Behandling av lakvatten inom avfallsdeponierna Syftet med projektet var att utvärdera den faktiska lakvattenreningskapaciteten inom Hedeskogas avfallsanläggning, Skånes län. Målet var även att mäta eventuell bakterieaktivitet i dess dammar, i vilka lakvattnet hanteras. Men vad är då lakvatten? Lakvatten produceras varje gång vatten infiltreras genom ämnen samt när olika sorters substanser samlas Dissolved ammonia is often referred to as one of the major contaminants in landfill leachates. Discharge concentration limits for municipal wastewater treatment plants in Sweden have been tightened in order to meet higher water quality standards. Because of REVAQ, a certification system tailored to ensure better sludge quality, wastewater treatment plants may decide whether to accept leachate from

Food trucks provide personalized experiences by eliminating anonymity and allowing the customer to slow down and engage. Their mobility facilitates transformation and a sense of occasion, thus possessing elements of performance, urgency and excitement. Having the ability to define spaces and revive locations, food trucks creates affiliative communities with natural meeting locations. The food truc

In several years after its discovery in the placenta, the human leukocyte antigen (HLA) class lb protein, HLA-G, was not given much attention, nor was it assigned great importance. As time has unraveled, HLA-G has proven to have distinctive functions and an unfore­ seen and possibly important role in reproduction. HLA-G is characterized mainly by its low polymorphism and restricted tissue distribu

MicroRNAs (miRNAs) are an exciting new field which has been connected to different cancers and cellular imbalances. In previous studies, our group has been able to find a correlation between miR-96 and prostate cancer (PC). Here we studied miR-96’s effect on the cell-cell adhesion protein E-cadherin’s RNA and protein expression levels upon miR-96 inhibition. Furthermore, because the bone is one of

The life stages of the sciarid fly Scatopsciara cunicularius and the effect of 3rd & 4th instar larval feeding on the bryophyte liverwort Marchantia polymorpha were studied in laboratory at two constant temperatures, 12.3 ± 0.6 ºC and 22.6 ± 1.7 ºC. A 14-hour period of light was provided during the 24-hour day/night-cycle. The experiments were carried out inside Petri dishes, at a relative hum

Vårt syfte med detta arbete var att undersöka hur synen på ojämlikheter bland barn och unga ser ut idag och vi valde att göra detta genom att samla in information från verksamma inom barn- och välgörenhetsorganisationer. Vi ville undersöka hur de diskuterar ojämlikheter, deras konsekvenser och i vilka sammanhang de anser att de uppkommer. Vi intervjuade fem personer, från olika organisationer, och

The focus of this work is to investigate and apply the remote sensing method of object-based image analysis (OBIA) for vegetation classification of a permafrost underlain peatland in sub-arctic Sweden, by using aerial imagery of high resolution. Since the northern landscapes are an important source of naturally stored CH4 and CO2, their contribution to the global carbon cycle is a focus in researc

This paper contains a study of the Nobel Peace Prize winner Liu Xiaobo’s texts on the Iraq war, and the implications of the problem representation encompassed in his view on the war. By use of the “What’s the problem represented to be?”- approach by Carol Bacchi, I have found that the problem representation in Liu Xiaobo’s texts on the Iraq war is “lack of democracy and freedom”. Because of the pr

Purpose: The purpose of this paper is to assess the sustainability of the efficient market theorem when accounting for extreme events, which are of the essence in a Black Swan investment philosophy. Methodology: Quantitative approach. Empirical foundation: Historical secondary monthly and daily data of various variables during January 1, 1996 - December 31, 2012. Conclusions: The Black Swan inv

Being the host of an Olympic Game can change the image of a city forever. The games last for only a month but the preparations begin many years before and the legacy lasts many years to come. In order to host the Olympic Games of 2008 Beijing underwent major changes and tore down old neighborhoods and replaced them with brand new buildings. Huge arenas, new landmarks, which will always be connecte

Glaciärer har visat sig vara känsliga för klimatologiska förändringar i sitt närområde och deras känslighet sträcker sig över flera olika tidsskalor. Glaciärerna har därför kommit att användas som indikatorer på både pågående och förhistoriska klimatförändringar. För att glaciärerna ska kunna spegla klimatet så krävs emellertid tillförlitliga mätmetoder av glaciärernas massa. I avsikt att återge gGlaciers integrate variations in climate over several different time scales and are thus used as indicators of both present and past climate change. It is however of importance to be able to correctly measure changes in the glaciers mass over time (the glaciers mass-balance), if one wishes to use the glaciers as climate indicators. The mass-balance of a glacier is a direct result of the glaciers a

This study is about the extent of how church law (of 1571, 1686 and 2000) in Sweden has affected and still affects the church's welfare administrations such as schools, hospitals and care institutions. Recent studies seem to indicate that the Church of Sweden is aiming to start expanding its organisation to include more social welfare activities to meet increasing demands from the general publ

Navigeringstjänster blir allt mer populära, men även om det finns en betydande mängd tjänster, finns det fortfarande begränsningar, speciellt för fotgängare. Fotgängare gör dagligen flera val om hur de ska hitta den bästa vägen i sin närmiljö. Att utveckla en navigeringstjänst för gående (PRNS) involverar flera viktiga faktorer. I denna studie analyseras flera befintliga nättjänster och studien viRoute network service is becoming increasingly popular. However, although there are significant amount of route network services there are still limitations especially to pedestrian network services. Pedestrians daily make decision about their navigation choices. Developing a pedestrian route network service (PRNS) involves several factors. During this study the analysis of several routing network

Advanced features of modern mobile devices have made it possible to develop and use maps and map based applications for navigation purposes. Since most mobile map applications nowadays are developed for motor vehicles, there is a demand for portable pedestrian navigation applications. In this thesis the Android mobile map application with standard navigation tools for pedestrian navigation was dev

The purpose of this thesis is to increase the understanding of the important elements for the local government when implementing sustainability in a city. By increasing the understanding of the important elements local governments are able to realize the critical factors in the implementation.