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Tunnelled lateral fasciocutaneous thoracodorsal flap with a skin island in breast reconstruction in oncoplastic breast surgery

The technique and results of a tunnelled lateral fasciocutaneous flap with a skin island is described in immediate partial breast reconstruction in a subpopulation in oncoplastic breast surgery. Fifteen patients were operated on from January 2008 to January 2011. The subpopulation consisted of patients with small or medium-sized breasts. All patients had invasive ductal carcinomas, located in the

ADAM10 and BACE1 are localized to synaptic vesicles.

Synaptic degeneration and accumulation of the neurotoxic amyloid β-peptide (Aβ) in the brain are hallmarks of Alzheimer disease. Aβ is produced by sequential cleavage of its precursor protein, APP, by the β-secretase BACE1 and γ-secretase. However, Aβ generation is precluded if APP is cleaved by the α-secretase ADAM10 instead of BACE1. We have previously shown that Aβ can be produced locally at th

Complexation and precipitation reactions in the ternary As(V)-Fe(III)-OM (organic matter) system

The predominant forms of arsenic (As) in anoxic and oxic environments are As(III) and As(V), respectively, and the fate of these forms is influenced by interactions with mineral surfaces and organic matter (OM). Interactions between As(V) and OM are believed to occur mainly via iron(Fe)-bridges in ternary Fe-arsenate complexes, but direct evidence for these interactions are scarce. Furthermore, si

Naturalization and Earnings: A Denmark-Sweden Comparison

The determinants and consequences of the naturalization of immigrants is a hot topic in the political debate in Europe. This article compares the effect of naturalization on the income attainment of immigrants in two Scandinavian countries, Denmark and Sweden, using longitudinal register data from 1986 and onward. Sweden is characterized by low obstacles to naturalization, and existing studies pro

The effects of counterion exchange on charge stabilization for anionic surfactants in nonpolar solvents

Hypothesis: Sodium dioctylsulfosuccinate (Aerosol OT or NaAOT) is a well-studied charging agent for model poly(methyl methacrylate) (PMMA) latexes dispersed in nonpolar alkane solvents. Despite this,few controlled variations have been made to the molecular structure. A series of counterion exchanged analogs of NaAOT with other alkali metals (lithium, potassium, rubidium, and cesium) were prepared,

Effects of Regioselectivity and Lipid Class Specificity of Lipases on Transesterification, Exemplified by Biodiesel Production

Lipase-catalyzed ethanolysis of triolein was studied as a model for biodiesel production. Four lipases were immobilized on porous polypropylene, and ethanolysis reactions were carried out in methyl t-butyl ether. The reaction products were analyzed using gas chromatography. Three of the four lipases studied were efficient in the conversion of triolein to 2-monoolein, but slow in the final step of

Identification of Novel Genetic Markers Associated with Clinical Phenotypes of Systemic Sclerosis through a Genome-Wide Association Strategy

The aim of this study was to determine, through a genome-wide association study (GWAS), the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis (SSc). We considered limited (IcSSc) and diffuse (dcSSc) cutaneous involvement, and the relationships with presence of the SSc-specific auto-antibodies, anti-centromere (ACA), and anti-topoisomerase I (ATA). Four GWAS

Prospectively measured triiodothyronine levels are positively associated with breast cancer risk in postmenopausal women

Introduction: The potential association between hypo-and hyperthyroid disorders and breast cancer has been investigated in a large number of studies during the last decades without conclusive results. This prospective cohort study investigated prediagnostic levels of thyrotropin (TSH) and triiodothyronine (T3) in relation to breast cancer incidence in pre- and postmenopausal women. Methods: In the

Mental disorders and vulnerability to homicidal death: Swedish nationwide cohort study

Objective To determine the risk of people with mental disorders being victims of homicide. Design National cohort study. Setting Sweden. Participants Entire adult population (n=7 253 516). Main outcome measures Homicidal death during eight years of follow-up (2001-08); hazard ratios for the association between mental disorders and homicidal death, with adjustment for sociodemographic confounders;

The efficiency of continuous regional intra-arterial infusion in the treatment of infected pancreatic necrosis

Objective: Our aim was to investigate the efficiency of continuous regional intra-arterial infusion (CRAI) with antisecretory agents and antibiotics in the treatment of infected pancreatic necrosis. Materials and methods: CRAI was used as a new clinical technique to treat acute pancreatitis patients during a 4-year period at the First Affiliated Hospital, Wenzhou Medical College, China. In this re

First therapeutic use of Artesunate in treatment of human herpesvirus 6B myocarditis in a child.

BACKGROUND: Human herpesvirus 6 (HHV-6) is an important cause of fulminant or acute viral myocarditis. However, insufficiency of standard antiviral treatment against HHV-6 is an emerging problem. OBJECTIVES: To describe the case of child with HHV-6 myocarditis who was treated by unloading with a left ventricular assist device and Artesunate. STUDY DESIGN: Case report supported by histological and

Thick Recognition: Advancing thoery on identity change in intractable conlficts

This study relates the concept of recognition to processes of conflict transformation. The recognition concept has been underdeveloped in recent IR literature, where the main emphasis has been on interstate relations and on recognition as cause of conflict. This article challenges that understanding through the introduction of the concept of thick recognition. Thus an understanding of recognition

Influence of salt ions on binding to molecularly imprinted polymers.

Salt ions were found to have an influence on template binding to two model molecularly imprinted polymers (MIPs), targeted to penicillin G and propranolol, respectively, in water-acetonitrile mixtures. Water was detrimental to rebinding of penicillin G whereas propranolol bound in the entire water-acetonitrile range tested. In 100% aqueous solution, 3-M salt solutions augmented the binding of both

Sexual force at sexual debut. Swedish adolescents with disabilities at higher risk than adolescents without disabilities

The aims of this study are first to compare the incidence of force on the first occasion of sexual intercourse reported by participants with disabilities to that of students without disabilities; second to determine whether there are significant differences in mental health, substance abuse, and school performance as reported by participants forced into their sexual debut as opposed to those who w

Measurement of W+W- production in pp collisions at root s=7 TeV with the ATLAS detector and limits on anomalous WWZ and WW gamma couplings

This paper presents a measurement of the W+W- production cross section in pp collisions at root s = 7 TeV. The leptonic decay channels are analyzed using data corresponding to an integrated luminosity of 4: 6 fb(-1) collected with the ATLAS detector at the Large Hadron Collider. The W+W- production cross section sigma(pp -> W+W- + X) is measured to be 51.9 +/- 2.0(stat) +/- 3.9(syst) +/- 2.0(lumi)

Binary classification of F-18-flutemetamol PET using machine learning: Comparison with visual reads and structural MRI

F-18-flutemetamol is a positron emission tomography (PET) tracer for in vivo amyloid imaging. The ability to classify amyloid scans in a binary manner as 'normal' versus 'Alzheimer-like', is of high clinical relevance. We evaluated whether a supervised machine learning technique, support vector machines (SVM), can replicate the assignments made by visual readers blind to the clinical diagnosis, wh

Comparison between capillary, venous and arterial levels of protein S100B in patients with severe brain pathology

Background: Protein S100B is soon in clinical use as a sensitive marker after mild traumatic head injury in adults. Initial studies of S100B in pediatric head injury have shown promising results. Venous sampling can be challenging in children and capillary samples are often a preferred option. The aim of the study was to investigate the relation between capillary, venous and arterial measurements

IL-9 Governs Allergen-induced Mast Cell Numbers in the Lung and Chronic Remodeling of the Airways

Rationale: IL-9 is a pleiotropic cytokine that has multiple effects on structural as well as numerous hematopoietic cells, which are central to the pathogenesis of asthma. Objectives: The contribution of IL-9 to asthma pathogenesis has thus far been unclear, due to conflicting reports in the literature. These earlier studies focused on the role of IL-9 in acute inflammatory models; here we have in