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Normal science and the hidden lemmas of mathematical epidemiology

Normal science is a characterization of science in our epoch and a demarcation of what “scientific” means. It divides science in disciplined/normed paradigms. Mathematical epidemiology is the paradigm that regulates the activity of mathematicians with respect to the study of epidemics. It also represents the interest (multiple meanings implied) of the community that guards it. In contrast, a real

Affinity-Purification Combined with Crosslinking Mass Spectrometry for Identification and Structural Modeling of Host-Pathogen Protein-Protein Complexes

Host-pathogen protein-protein interactions are highly complex and dynamic and mediate key steps in pathogen adhesion to host, host invasion, and colonization as well as immune evasion. In bacteria, these interactions most often involve specialized virulence factors or effector proteins that specifically target central host proteins. Here, I present a mass spectrometry-based proteomics approach sta

Unstructured Interviews – A Conversational Iceberg

My ongoing work on the lived experiences of young adult migrants is phenomenological research aimed at the process of social resilience and social experiences of young adult migrants. I'm conducting unstructured interviews to learn more about the phenomenon's textural (what was experienced) and structural (how it was experienced) characteristics. In these unstructured interviews, I emphasize the m

Laboratory Experiments on Soil Stabilization to Enhance Strength Parameters for Road Pavement

Clay soils can cause significant distress in road construction due to their low strength. Stabilizing such soil improve with binder agents prior to the geotechnical works can significantly its performance and ensure safety and stability of roads while exploitation. This research envisaged the use of five different binders (lime, energy fly ash, bio fly ash, slag, cement) as an additive stabilizing

Effects of adsorbed molecular ordering to the superconductivity of a two-dimensional atomic layer crystal

The effect of 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) adsorption on the physical properties of the two-dimensional (2D) atomic layer superconductor (ALSC) In/Si(111)-(7×3) has been studied by angle-resolved photoelectron spectroscopy, transport measurements, and scanning tunneling microscopy. Hole doping from the adsorbed molecules has been reported to increase the superconducting tra

Direct observation of large-area strain propagation on free-standing nanomembranes

Investigations on epitaxial nanostructures with size of tens of nanometers have been a challenging issue for techniques that present high strain sensitivity but restricted spatial resolution. This is the case of recently developed x-ray nanoprobe techniques. Despite its inherent nondestructive character, submicron x-ray spots have only been successfully applied to the study of individual nanostruc

Multiplicity fluctuations and correlations in 5.02 TeV p+Pb collisions at zero impact parameter

We present a Bayesian method to reconstruct event-by-event multiplicity fluctuations and rapidity correlations in p+Pb collisions at zero impact parameter from minimum-bias data, without assuming any model of the collision dynamics. We test it on Monte Carlo simulations with the Angantyr model, then apply it to ATLAS data on the distribution of charged multiplicity and transverse energy in p+Pb co

Plasma Galectin-4 Levels Are Increased after Stroke in Mice and Humans

Epidemiological studies have associated plasma galectin-4 (Gal-4) levels with prevalent and incident diabetes, and with an increased risk of coronary artery disease. To date, data regarding possible associations between plasma Gal-4 and stroke are lacking. Using linear and logistic regression analyses, we tested Gal-4 association with prevalent stroke in a population-based cohort. Additionally, in

Urban Cemeteries and the Aesthetics of Care

Even though urban cemeteries in Sweden today can be seen as making space for different memorial practices, they are also a materialization of certain cultural and religious norms (Kjaersgaard & Venbrux, 2016), which sometimes are expressed as functional and aesthetic values. In this respect, the urban cemetery has an abiding attitude to change in building on past traditions and designs to addrEven though urban cemeteries in Sweden today can be seen as making space for different memorial practices, they are also a materialization of certain cultural and religious norms (Kjaersgaard & Venbrux, 2016), which sometimes are expressed as functional and aesthetic values. In this respect, the urban cemetery has an abiding attitude to change in building on past traditions and designs to addr

Precision Prognostics for Cardiovascular Disease in Type 2 Diabetes : A Systematic Review and Meta-analysis

BACKGROUND: Precision medicine has the potential to improve cardiovascular disease (CVD) risk prediction in individuals with type 2 diabetes (T2D).METHODS: We conducted a systematic review and meta-analysis of longitudinal studies to identify potentially novel prognostic factors that could improve CVD risk prediction in T2D. Out of 9380 studies identified, 416 studies met inclusion criteria. Outco

Countering the Proliferation of Plastic Waste through Circularity

How can the circular economy address the challenges of plastic waste? By rethinking production, distribution, and consumption patterns. It is a complex challenge that necessitates ethical, cultural, technical, and social considerations, far beyond managerial concerns. Recirculating some plastic and taking out the rest will require unraveling deeply embedded practices and choices in society.

The circular economy: a geometry lesson

To maintain its transformational potential, the circular economy needs to be associated with an actual closing of material loops, recognising that this entails a new balance of power among corporations, customers and those who work with material recovery—not least waste pickers in the global south. The environmental footprint of production and consumption must be reduced, through decreased extract

An intricate dance of intersubjectivity : The social and cognitive benefits of a digital shared reading group

This article deepens the understanding of characteristic features of Shared Reading (SR) that can shed light on health benefits of this literary practice suggested by previous research. We provide a detailed analysis of language, interaction, reading strategies and collaborative meaning-making in an online SR group in which participants read and discussed a modernist poem. We triangulate our analy

Brott har lönat sig

For many young boys on the loose, crime pays off, write researchers Ardavan Khoshnood and Sten Levander. But with early interventions, we can probably slow down gang crime.

Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture

Background: Atherosclerotic plaque ruptures, triggered by blood flow–associated biomechanical forces, cause most myocardial infarctions and strokes. Objectives: This study aims to investigate the exact location and underlying mechanisms of atherosclerotic plaque ruptures, identifying therapeutic targets against cardiovascular events. Methods: Histology, electron microscopy, bulk and spatial RNA se