The development of an alpha synuclein overexpressing In vitro model for parkinson's disease research
Abstract Parkinson’s disease (PD) is characterized by selective loss of dopaminergic neurons and progressive accumulation of intracellular alpha synuclein protein aggregates known as Lewy bodies. Due to pathological links to both sporadic and inherited cases of PD, alpha synuclein (asyn) has become a focal point for study, although the exact mechanisms of its toxicity are not known. In contrast to