Giant cell arteritis (GCA), affects an age group where osteoporosis is common. A well-established treatment for osteoporosis is medication with bisphosphonates. Bisphosphonates are overall well-tolerated but can trigger several different acute inflammatory reactions with systemic features and symptoms and signs from the ocular and musculoskeletal system, all of which resemble those of GCA. Here is

This paper discusses the key legal issues arising from the constitutional conceptions of both the EU and the UK in the latter’s withdrawal process. It argues that the adherent Brexit dilemma is mainly the result of the UK’s non-codified constitution on the one hand, exposing legal uncertainty over institutional procedures, regional involvement, or the precise status of international law. Neverthel

The coherent generation of synchrotron radiation by an electron storage ring is predicted for wavelengths equal to or longer than the electron bunch length. With typical bunch lengths of approximately 1 cm, diffraction and chamber- screening effects have so-far blocked observation of coherent radiation from a conventional radiation beam line. In the low-energy, second-generation light source MAX-I

Passive Landau cavities have been built, installed and taken into regular operation in the MAX II ring. The purpose of the Landau damping system is twofold: to decrease the energy spread of the beam induced by coupled bunch oscillations and to increase the Touschek life-time. The cavities are of the pillbox type operated at 1500 MHz, the third harmonic of the main RF. This paper describes the desi

An undulator with short poles (period 24 mm) and extremely narrow gap (magnet gap 7.7 mm) using a squeezable vacuum chamber has been installed and is in operation at the MAX-lab 550 MeV storage ring. The device operates with a vacuum chamber aperture down to 6.2 mm. The behaviour of the storage ring concerning lifetime, emittance, tune shift and closed orbit is well described by conventional model

An electron beam profile monitor system is described. It utilizes the visible bending magnet synchrotron radiation (SR) to form an image of the beam. A model for calculating diffraction and depth of field effects is introduced. Assuming a Gaussian distributed electron beam, the relation between beam image size and actual beam size is then calculated with this model, for a number of practical measu

At the synchrotron radiation facility MAX, the rest gas pressure in the storage rings is dominated by synchrotron radiation induced gas desorption. This desorption decreases with accumulated photon dose. The rate of decrease, or conditioning, is of greatest importance, since an acceptable machine performance, after opening the vacuum system, is highly dependent on the vacuum recovery. In MAX II th

In this report, we first discuss some different pre-injector possibilities for the ESRF booster synchrotron, using estimated machine performances. We then focus on the commercially available linac schemes carrying out more detailed calculations. We also look into the possibility of recyling the particles through the linacs.

A 1.5 GeV third generation storage ring optimised for the VUV and soft X-ray spectral region is currently being built at MAX-lab. The magnet lattice, ring architecture and production choices are optimised to fit within rather tight boundary conditions without sacrificing performance. In this paper, the magnet lattice, light characteristics, injection and technical solutions for the ring are presen

Lipid auto-oxidation in milk is affected by a complex interplay of pro- and antioxidants. Several of these compounds are also important nutrients in the human diet and may have other physiological effects in the gastrointestinal tract and other tissues. Among antioxidative enzymes superoxide dismutase catalyses the dismutation of superoxide anion to hydrogen peroxide. The degradation of hydrogen p

Background.In some regions, including the Baltic Sea, fatty fish such as salmon and herring contain high levels of polychlorinated dibenzodioxins and dibenzofurans. We investigated human exposure to these potentially toxic substances in relation to the consumption of fish from the Baltic Sea.Methods.Plasma levels of 10 different dibenzofurans and 7 dioxins were analyzed in three groups of Swedish

We study transportation networks controlled by dynamical feedback tolls. We consider a multiscale transportation network model whereby the dynamics of the traffic flows are intertwined with those of the drivers' route choices. The latter are influenced by the congestion status on the whole network as well as dynamic tolls set by the system operator. Our main result shows that a broad class of dece

The spread of new beliefs, behaviors, conventions, norms, and technologies in social and economic networks are often driven by cascading mechanisms, and so are contagion dynamics in financial networks. Global behaviors generally emerge from the interplay between the structure of the interconnection topology and the local agents' interactions. We focus on the Threshold Model (TM) of cascades first

We consider a broad class of stochastic imitation dynamics over networks, encompassing several well known learning models such as the replicator dynamics. In the considered models, players have no global information about the game structure: they only know their own current utility and the one of neighbor players contacted through pairwise interactions in a network. In response to this information

Most expression quantitative trait locus (eQTL) studies to date have been performed in heterogeneous tissues as opposed to specific cell types. To better understand the cell-type-specific regulatory landscape of human melanocytes, which give rise to melanoma but account for

Imitation dynamics for population games are studied and their asymptotic properties analyzed. In the considered class of imitation dynamics - that encompass the replicator equation as well as other models previously considered in evolutionary biology - players have no global information about the game structure, and all they know is their own current utility and the one of fellow players contacted

The IEEE Control Systems Society (CSS) Technical Committee on Networks and Communication Systems (TC-NCS) focuses on areas that involve the interplay among networks, communication, and systems control. The TC is organized into eight working groups, Control of Network Systems, Information Networks and Control, Networked Sensing and Sensor Networks, Optimization and Game Theoretic Methods in Network

Background: Full-term pregnancy (FTP) is associated with a reduced breast cancer (BC) risk over time, but women are at increased BC risk in the immediate years following an FTP. No large prospective studies, however, have examined whether the number and timing of pregnancies are associated with BC risk for BRCA1 and BRCA2 mutation carriers.Methods: Using weighted and time-varying Cox proportional