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Constructions of migrant victims of labor exploitation in Nordic court cases

The aim of this article is to explore how courts produce certain representations of victims of labor exploitation in the Nordic context based on court judgements from Denmark, Finland, Norway and Sweden. To achieve this, we analyze and compare criminal court judgements focused on the exploitation of migrant workers by asking: How are ‘victims’ of labor exploitation represented in Nordic court judg

Evaluating the affinity and kinetics of small molecule glycomimetics for human and mouse galectin-3 using surface plasmon resonance

Galectin-3 is a beta-galactoside-binding mammalian lectin that is one of a 15-member galectin family that can bind several cell surface glycoproteins via its carbohydrate recognition domain (CRD). As a result, it can influence a range of cellular processes including cell activation, adhesion and apoptosis. Galectin-3 has been implicated in various diseases, including fibrotic disorders and cancer,

Novel inhibitory effect of galectin-3 on the respiratory burst induced by Staphylococcus aureus in human neutrophils

Among the responders to microbial invasion, neutrophils represent the earliest and perhaps the most important immune cells that contribute to host defense with the primary role to kill invading microbes using a plethora of stored anti-microbial molecules. One such process is the production of reactive oxygen species (ROS) by the neutrophil enzyme complex NADPH-oxidase, which can be assembled and a

Safety and pharmacokinetics of GB1211, an oral galectin-3 inhibitor : a single- and multiple-dose first-in-human study in healthy participants

PURPOSE: Galectin-3, a β-galactoside-binding lectin, plays a key role in several cellular pathways involved in chronic inflammation, heart disease and cancer. GB1211 is an orally bioavailable galectin-3 inhibitor, developed to be systemically active. We report safety and pharmacokinetics (PK) of GB1211 in healthy participants.METHODS: This phase 1, double-blind, placebo-controlled, first-in-human

Access to justice and social rights for victims of trafficking and labour exploitation in Sweden

This chapter delves into the challenges encountered by victims of human trafficking and other forms of labour exploitation in Sweden as they struggle to access social rights and justice. By drawing from theories of victimisation as an interactional process, the study examines the role of professionals such as government agents, social services, unions, and NGOs as facilitators in assisting victimsThis chapter delves into the challenges encountered by victims of human trafficking and other forms of labour exploitation in Sweden as they struggle to access social rights and justice. By drawing from theories of victimisation as an interactional process, the study examines the role of professionals such as government agents, social services, unions, and NGOs as facilitators in assisting victims

Acute and Long-Term Changes in Blood-Borne Biomarkers in Response to Dynamic Standing in Nonambulant Children With Cerebral Palsy

PURPOSE: To investigate acute and long-term changes in hormonal and inflammatory biomarkers in nonambulant children with cerebral palsy in response to dynamic standing exercise.METHODS: Fourteen children with severe cerebral palsy were recruited. Anthropometrics and body composition measures were obtained. Physical activity levels before the study were assessed using hip-worn accelerometry. All ch

"It is something that gives us hope" : Lived experience among parents to children with cerebral palsy who are non-ambulant of the phenomenon physical activity, with or without the use of a novel dynamic standing device

INTRODUCTION: Regular physical activity confers health benefits for all. Parents commonly want their children to be physically active, and want to be physically active themselves, but children with cerebral palsy (CP) who are non-ambulant face challenges, and they need support to be physically active. Dynamic standing in the novel motorized assistive device Innowalk has positive effects in childre

Spatially Guided and Single Cell Tools to Map the Microenvironment in Cutaneous T-Cell Lymphoma

Mycosis fungoides (MF) and Sézary syndrome (SS) are two closely related clinical variants of cutaneous T-cell lymphomas (CTCL). Previously demonstrated large patient-to-patient and intra-patient disease heterogeneity underpins the importance of personalized medicine in CTCL. Advanced stages of CTCL are characterized by dismal prognosis, and the early identification of patients who will progress re

The External Dimensions of the European Union's Autocracy Crisis

This contribution analyses the external dimensions of the EU’s autocracy crisis. It argues that the internal and external dimensions of the crisis, and those relating to accession, are interlinked, and that more genuine social democracy, human rights, and rule of law would help address the crisis. It concludes that a paradigm shift to a holistic approach is needed to understand and address the cau

Gradient-based optimization of non-linear structures and materials

Gradient-based optimization is a potent tool in many design processes today. It is particularly useful in industries where weight considerations are crucial, such as aerospace, but can also be exploited in for example civil engineering applications to reduce the material use and thereby the environmental impact. With the advent of advanced manufacture methods, it even possesses the potential to de

Reduced Vestibulo-Ocular Reflex During Fast Head Rotation in Complete Darkness

The human vestibulo-ocular reflex (VOR) leads to maintenance of the acuity of an image on the retina and contributes to the perception of orientation during high acceleration head movements. Our objective was to determine whether vision affects the horizontal VOR by assessing and comparing the performance at the boundaries of contribution of: (a) unrestricted visual information and (b) no visual i

Turbulent premixed flames in a model gas turbine combustor: fuel sensitivity and flame dynamics

The demand for energy security and reduction of greenhouse gas emissions has led to a surge of interest in the development of high-efficiency and low-emission gas turbine engines that can run on alternative low carbon content fuels, such as hydrogen-enriched fuel and syngas. However, the combustion characteristics of these fuels can significantly alter the flame characteristics and operability ran

Dissolved Organic Matter from a colloidal perspective

Dissolved organic matter (DOM) is considered the most bioavailable fraction of soil, and thus play a key role in the cycling of carbon. Because of its mobility, DOM also forms the connection between terrestrial and aquatic systems, and constitutes an important vector for nutrients and contaminants. DOM is in this thesis operationally defined as the organic matter in an aqueous solution which is no