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Background and aims: Ethnicity influences the prevalence of gestational diabetes (GDM) and its progression to manifest diabetes postpartum, being higher in non-European populations. This may partly be explained by differences in insulin secretion and action. Aims of the present study were to evaluate glucose homeostasis after GDM, the impact of ethnicity and other determinants of glucose toleranceBackground and aims: Ethnicity influences the prevalence of gestationaldiabetes (GDM) and its progression to manifest diabetes postpartum, beinghigher in non-European populations. This may partly be explained by differences in insulin secretion and action. Aims of the present study were toevaluate glucose homeostasis after GDM, the impact of ethnicity and otherdeterminants of glucose tolerance pos

Most signals detected by genome-wide association studies map to non-coding sequence and their tissue-specific effects influence transcriptional regulation. However, key tissues and cell-types required for functional inference are absent from large-scale resources. Here we explore the relationship between genetic variants influencing predisposition to type 2 diabetes (T2D) and related glycemic trai

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), causing Coronavirus Disease 19 (COVID-19), emerged at the end of 2019 and quickly spread to cause a global pandemic with severe socio-economic consequences. The early sequencing of its RNA genome revealed its high similarity to SARS, likely to have originated from bats. The SARS-CoV-2 non-structural protein 10 (nsp10) displays high sequ

The rationale was to longitudinally follow-up interviews performed with heart recipients at their one-year examination in order to deepen the understanding of the meaning of surviving a heart transplant. The aim was to explore the meaning of surviving three years after a heart transplant compared to one year and to identify what constitutes the change process. A phenomenological–hermeneutic method

Food additives such as emulsifiers are used in increasing quantities in the food industry. The aim of this study was to compare three different emulsifiers (polysorbate 80 (P80), carboxymethyl cellulose (CMC), and β-lactoglobulin (β-lac) with regards to their effect on the stimulation of immune cells and intestinal permeability. The immune stimulatory effects were studied in the myeloid cell line

During the last decade, personal assistance programs have suffered from cutbacks, resulting in a public debate about the future of the service. This debate has largely been framed by public commission estimations of the level of incorrect personal assistance payments, where the idea that circa 10% of all assistance payments are incorrect repeatedly has been used to justify measures designed to dec

Parent-of-origin effects (POE) and sex-specific parental effects have been reported for plasma lipid levels, and a strong relationship exists between dyslipidemia and obesity. We aim to explore whether genetic variants previously reported to have an association to lipid traits also show POE on blood lipid levels and obesity. Families from the Botnia cohort and the Hungarian Transdanubian Biobank (

The integrated nature of the Sustainable Development Goals (SDGs) presents a challenge to implementing the 2030 Agenda. Analytical methods to support decision-makers are often developed without explicitly incorporating decision-makers’ views and experience. Here, we investigate whether existing methods are fit-for-purpose in supporting decision-makers at national and subnational levels. We identif

Entangled logics, which attribute meaning to security, characterise the contemporary security field, bringing about broad comprehensions and ambiguous concepts. Civil defence has (re)surfaced as one such concept that is broadly conceived in the official discourses produced by decision-makers. Since security is ultimately enacted by practitioners, alias decision-takers, their interpretations of con

Current scholarship on race in Europe has described race as an “absent presence”. However, little is known about the dynamics of the absentness and presentness of race, including how various social processes operating at distinct levels (e.g., supranational and national) influence the uses of race and ethnicity concepts. We begin addressing this gap by examining racialised pharmaceutical regulatio

Dysphagia, or difficulty swallowing, affects 10–30 % of persons above 65 years old. Texture-modified, easy-to-swallow, puree-like food in the form of timbales is usually served to this group of patients. Due to the characteristics of timbale, its appearance only remotely reminds of the original ingredients, leading to reduced appetite, reduced nutrition intake, and even malnutrition. 3D food print

Plasmodium falciparum malaria can cause severe anemia. Even after treatment, hematocrit can decrease. The role of autoantibodies against erythrocytes is not clearly elucidated and how common they are, or what they are directed against, is still largely unknown. We have investigated antibodies against erythrocytes in healthy adult men living in a highly malaria endemic area in Uganda. We found anti

Neurotensin (NT) is a small peptide with pleiotropic functions, exerting its primary actions by controlling food intake and energy balance. The first evidence of an involvement of NT in metabolism came from studies on the central nervous system and brain circuits, where NT acts as a neurotransmitter, producing different effects in relation to the specific region involved. Moreover, newer interesti

Background: The WHO advises against recumbent position for longer periods during labour and birth. It has been suggested that upright posi-tions may improve childbirth outcomes and reduce the need for oxytocin augmentation. However RCTs of interventions to encourage upright positions are scarce. The aims of this study were to assess whether there is a relationship between the use of oxytocin augme

Objective. Experimental determination of beam quality k Q factors for two types of Farmer ionization chambers, NE2571 and IBA FC65-G, in a scanned proton beam for three nominal energies (140 MeV, 180 MeV and 220 MeV) based on water calorimetry. Approach. Beam quality correction factors were determined comparing the results obtained with water calorimetry and ionometry. Water calorimetry was perfor

Recent years have witnessed major changes to the workplace across Europe. The speed of these changes requires constant monitoring and reappraisal. In this book, recent trends are analyzed and their consequences discussed, within a socio-historical context which also reveals underlying patterns of continuity. The trends analyzed include: the presence of high rates of endemic unemployment and undere