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Using a Targeted Proteomics Chip to Explore Pathophysiological Pathways for Incident Diabetes- The Malmö Preventive Project

Multiplex proteomic platforms provide excellent tools for investigating associations between multiple proteins and disease (e.g., diabetes) with possible prognostic, diagnostic, and therapeutic implications. In this study our aim was to explore novel pathophysiological pathways by examining 92 proteins and their association with incident diabetes in a population-based cohort (146 cases of diabetes

Tillbaka till dåtiden? : Om bibelvetenskapens roll och metoder : En replik till Joel Halldorf

The exegetical subjects have a particular interdisciplinary role within academia, implying that their responsibilities and significance are – and should be – under constant debate. In his article, church historian Joel Halldorf, argues for the overt use of theological interpretations (in the narrow sense of "normative theology") in the exegetical discipline. Halldorf thereby highlights some currenThe exegetical subjects have a particular interdisciplinary role within academia, implying that their responsibilities and significance are – and should be – under constant debate. In his article, church historian Joel Halldorf, argues for the overt use of theological interpretations (in the narrow sense of "normative theology") in the exegetical discipline. Halldorf thereby highlights some curren

Local initiatives and global regimes - Multi-scalar transition dynamics in the chemical industry

The breaking with regime logics is one of the key leverage points to enable a socio-technical transition. Understanding how, and under what conditions, this may happen is thus an important task for transition studies. Recent research on socio-technical regimes has shown that they may be less geographically bound than previously assumed. Regimes may instead be replicated and reinforced globally thr

Linking, Searching, and Visualizing Entities in Wikipedia

In this paper, we describe a new system to extract, index, search, and visualize entities in Wikipedia. To carry out the entity extraction, we designed a high-performance, multilingual, entity linker and we used a document model to store the resulting linguistic annotations. The entity linker, HEDWIG, extracts the mentions from text usinga string matching Engine and links them toentities with a co

A tool for sourcing sustainable building renovation : The energy efficiency maturity matrix

The success of sustainable building renovation is inevitably dependent on the capabilities of the involved stakeholders throughout the entire project. Therefore, any building client with intentions of sustainable building renovations must reflect on sourcing the adequate capabilities for a sustainable renovation project. The question in focus is: how to facilitate a sourcing strategy for energy-ef

Predictors and mediators of outcome in CBT for chronic pain : The roles of psychological flexibility and PTSD

Långvarig smärta är ett vanligt förekommande och tärande tillstånd som är bland de mest kostsamma hälsoproblemen för både individen och samhället som helhet. Kognitiv beteendeterapi (KBT) är den mest spridda psykologiska behandlingen för långvarig smärta. Även om metoden är evidensbaserad och rekommenderad ger den relativt blygsamma förbättringar för smärtrelaterad funktion och medföljande emotionChronic pain is a commonly occurring and debilitating condition, and among the costliest health problems for both the individual and society at large. Cognitive behavioral therapy (CBT) is the most widely-disseminated psychological treatment for chronic pain. Even though it is recommended and evidence-based, it yields quite modest improvements in pain-related functioning and accompanying symptoms

Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates

AMP-activated protein kinase (AMPK) is a key regulator of cellular energy homeostasis, acting as a sensor of energy and nutrient status. As such, AMPK is considered a promising drug target for treatment of medical conditions particularly associated with metabolic dysfunctions. To better understand the downstream effectors and physiological consequences of AMPK activation, we have employed a chemic

Medeltidsarkeologi 1983-2009, förmedling, representativitet och ansvar

Even when the editor of the popular journal Populär Arkeologi claims to be communicating the latest advances in archaeological research to the public and that the authors often are professional archaeologists, this is done very rarely and focuses mostly on dating and artifacts. Is it the editor’s responsibility or must the archaeologists themselves highlight these issues in their articles? Common

Networked authority and regionalised governance : Public transport, a hierarchy of documents and the anti-hierarchy of authorship

This paper is concerned with the authority of written documents and how these artefacts work as governance devices. Networked authority is introduced as a concept to elucidate how documents accumulate formal power in a collaborative process, where several formally independent but informally interdependent organisations together point out the direction of regional public transport planning in the f

Localizing SDGs : the case of city planning in Malmö

Cities have an important role to play in implementing the UN Sustainable Development Goals (SDGs) and to mobilize sustainability at the urban level. Yet, municipalities encounter challenges in localizing the SDGs into their governance structures, and there is a need to advance our understanding of cities strengths and weaknesses in such processes. In this article we provide knowledge and reflectio

Monitoring internal erosion in embankment dams using 3D Electrical Resistivity Tomography: Älvkarleby test embankment dam

One major risk threatening embankment dam integrity is internal erosion of the core. Internal erosion progresses inside the dam but it is difficult to detect with conventional methods. Electrical Resistivity Tomography (ERT) is a potential-based method that can sense the interior of the dam, and this study aims to evaluate the capability of ERT as a complementary monitoring technique for discoveri

Moisture Buffering of Hemp-Lime with Biochar and Rape Straw-Lime as Surface Materials for a Stable Indoor Climate

An appropriate and stable indoor climate in museums is crucial to guarantee an appropriate preservation of our cultural heritage. Depending on the collection, indoor temperature and relative humidity need to be kept within a certain range. Fluctuations in temperature and relative humidity could cause damage to museum artefacts and may require higher energy needs than necessary. Biochar is a materi