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Little is known about the nature of post mortem degradation of proteins and peptides on a global level, the so-called degradome. This is especially true for non-neural tissues. Degradome properties in relation to sampling procedures on different tissues are of great importance for the studies of for instance post translational modifications and/or the establishment of clinical biobanks. Here, snap

Background. R-Limonene is a common fragrance terpene found in domestic and industrial products. R-Limonene autoxidizes on air exposure, and the oxidation products can cause contact allergy. In a recent multicentre study, 5.2% (range 2.3-12.1%) of 2900 patients showed a positive patch test reaction to oxidized R-limonene. Objective. To study the exposure to limonene among consecutive dermatitis pat

Background: So far there are no studies comparing the attitudes of patients with hereditary conditions to the attitudes of the general public on how to handle genetic risk information which mutation carriers refuse to disclose to relevant family members. The purpose of the present study was to investigate whether such patients and members of the general public want to be informed about the existen

The incidence of type 1 diabetes (T1D) is increasing, either because of environmental factors accelerating onset of the disease or because of inducement of autoimmune diabetes in children who previously were at lower risk. High levels of immunoglobulin (Ig), specifically, IgM and IgA, and a low level of IgG were reported in adult patients; however no studies have analyzed the increasing incidence

Neighborhood characteristics have been associated with both depression and diabetes, but to date little attention has been paid to whether the association between depression and diabetes varies across different types of neighborhoods. This prospective study examined the relationship between depression, neighborhood deprivation, and risk of type 2 diabetes among 336,340 adults from a national-repre

Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass index, waist circumference, hip circumference, and waist-to-hip-ratio (133,723 individuals) and took forward 348 SNPs into follow-up (additional 137,052 individuals) in a total of

The grocery retail industry, with its large product volumes, low margins and fierce competition, is constantly seeking efficiency improvements in its supply chain. The grocery retail industry uses an immense amount of packaging and is directly affected by packaging logistics activities. There is, therefore, a potential for efficiency improvements in the grocery retail supply chain through the inte

The autoimmune disease Systemic Lupus Erythematosus is associated with hereditary deficieny of early components from the classical pathway of complement activation, but not with deficiency of complement component C3 or of the alternative pathway components. The classical pathway is involved in elimination of pathological immune complexes from the circulation by transport via complement receptor ty

The best mode of delivery for fetuses with intrauterine growth restriction (IUGR) and umbilical artery (UA) blood flow changes is not well elucidated. Uterine artery, fetal UA, middle cerebral artery (MCA), and venous blood flow changes during uterine contractions during an oxytocin challenge test (OCT) have not been observed systemically. AIMS: To evaluate outcome in IUGR with UA blood flow chang

The 16O(gamma,pn) reaction has been measured with a resolution high enough to resolve individual low-lying states in the residual 14N nucleus. The relative population of the states provides detailed information about the quantum numbers of the proton-neutron pairs on which photons are absorbed. Partial cross-sections, available to the acceptance of the detector system, have been extracted for the

Antibodies are important protein structures in the immunological defence. Occasionally the regulation of the production of these antibodies fails and antibodies directed against self structures are produced in large scale. Antibody production can also complicate or make transfusions and transplantations impossible. Purified protein A from Staphylococcus aureus immobilised to beaded agarose can ads

The rapid developments within the life science and biotechnology areas put up ever-new demands on more sophisticated techniques and methods for chemical and biological analysis to reach deeper insight into the events at molecular level. Miniaturisation of assays and systems on microchips is one way to increase throughput and advance through parallel analysis lines, multiplexing and integration. Th