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The increased electrification of society and the development of smart grids are often seenas central in the transition towards a more sustainable and secure energy system and necessaryto address the challenges of increasing energy demand and limited resources. Thereare many visions and ideas on what a smart grid is or could be. While most research relatedto environmental impacts on the smart grid
Hybridization allows adaptations to be shared among lineages and may trigger the evolution of new species1,2. However, convincing examples of homoploid hybrid speciation remain rare because it is challenging to demonstrate that hybridization was crucial in generating reproductive isolation3. Here we combine population genomic analysis with quantitative trait locus mapping of species-specific trait
Postural tachycardia syndrome (POTS) is a chronic autonomic disorder characterized by excessive heart rate elevation upon standing or head-up tilt, in the absence of orthostatic hypotension. This debilitating condition affects primarily young to middle-aged individuals, particularly women, and substantially influences quality of life. The main presenting symptoms are lightheadedness, palpitations,
Recent research suggests that to help their preferred coalition win an election, voters are willing to vote for a political party other than their preferred choice. In this field, voting for smaller parties under proportional representation is an under-studied feature. A crucial factor to estimate the chances for smaller parties is polls. In this study, we analyze the influence of opinion polls on
Nonclusion is aligned with Universal Design and involves a critical approach to the categorisation of people. Specifically, nonclusion resists categorisations of bodies/roles and does not come with predefined or presupposed limits in terms of who something is meant for. While UD and nonclusion generally target Design and Architecture, this article explores how nonclusion can be conveyed through te
Housing provisions in the Western world, Australia included, are characterised by several challenges. New residential typologies are needed to cope with, for example, environmental and economic considerations of land use, escalating construction cost, and the lack of affordable housing. Urban form determines measures of density. It also spurs our common imaginaries of urban life. Hence,to calibrat
Endoplasmic reticulum (ER) membrane resident P5A-ATPases broadly affect protein biogenesis and quality control, and yet their molecular function remains debated. Here, we report cryo-EM structures of a P5A-ATPase, CtSpf1, covering multiple transport intermediates of the E1 → E1-ATP → E1P-ADP → E1P → E2P → E2.Pi → E2 → E1 cycle. In the E2P and E2.Pi states a cleft spans the entire membrane, holding
Outcome under-ascertainment, characterized by the incomplete identification or reporting of cases, poses a substantial challenge in epidemiologic research. While capture-recapture methods can estimate unknown case numbers, their role in estimating exposure effects in observational studies is not well established. This paper presents an ascertainment probability weighting framework that integrates
This article summarizes the state of the science on the role of the gut microbiota (GM) in diabetes from a recent international expert forum organized by Diabetes, Diabetes Care, and Diabetologia, which was held at the European Association for the Study of Diabetes 2023 Annual Meeting in Hamburg, Germany. Forum participants included clinicians and basic scientists who are leading investigators in
This article summarises the state of the science on the role of the gut microbiota (GM) in diabetes from a recent international expert forum organised by Diabetes, Diabetes Care, and Diabetologia, which was held at the European Association for the Study of Diabetes 2023 Annual Meeting in Hamburg, Germany. Forum participants included clinicians and basic scientists who are leading investigators in
A strong and prevailing innovation imperative is sweeping across the public sector and despite a growing literature on public sector innovation (PSI), the actors driving these processes tend to end up in the background of analysis. Based in an analytical framework of narrative theory and organization studies, and the efforts to introduce Social Impact Bonds (SIB) in Sweden as empirical case, the a
The aim of this study was to add knowledge of the longitudinal associations between gaming and emotional closeness between parents and their children. We hypothesized that parent–child emotional closeness was linked to less gaming activity over time and that more gaming activity was linked to less parent–child emotional closeness over time. We also tested the moderating effect of child gender on t
