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Impact of temperature dependent sampling procedures in proteomics and peptidomics – A characterization of the liver and pancreas post mortem degradome

Little is known about the nature of post mortem degradation of proteins and peptides on a global level, the so-called degradome. This is especially true for non-neural tissues. Degradome properties in relation to sampling procedures on different tissues are of great importance for the studies of for instance post translational modifications and/or the establishment of clinical biobanks. Here, snap

Positive patch test reactions to oxidized limonene: exposure and relevance

Background. R-Limonene is a common fragrance terpene found in domestic and industrial products. R-Limonene autoxidizes on air exposure, and the oxidation products can cause contact allergy. In a recent multicentre study, 5.2% (range 2.3-12.1%) of 2900 patients showed a positive patch test reaction to oxidized R-limonene. Objective. To study the exposure to limonene among consecutive dermatitis pat

How to Handle Genetic Information: A Comparison of Attitudes among Patients and the General Population

Background: So far there are no studies comparing the attitudes of patients with hereditary conditions to the attitudes of the general public on how to handle genetic risk information which mutation carriers refuse to disclose to relevant family members. The purpose of the present study was to investigate whether such patients and members of the general public want to be informed about the existen

Improved diagnostic accuracy in patients with suspected appendicitis

Background: Studies during the 1990s showed that it was possible to reduce the rate of negative appendectomies by using various diagnostic methods. The present study aims to evaluate the effect on diagnostic accuracy of implementation of repeated clinical examination and blood tests in a small county hospital without possibilities of radiological assistance on a 24-hour basis. Methodology: Prospec

Strategies for feeling secure influence parents' participation in care

This study investigates what makes parents of hospitalized children feel secure and factors influencing their level of participation. It also studies, whether the degree to which parents participate affects their child's pain and sleep during hospitalization. Questionnaires were distributed to a series of parents whose children were discharged from two paediatric surgical wards and one paediatric

A homozygous nonsense mutation (428G -> A) in the human secretor (FUT2) gene provides resistance to symptomatic norovirus (GGII) infections

Noroviruses (formerly Norwalk-like viruses) are a major cause of acute gastroenteritis worldwide and are associated with a significant number of nosocomial and food-borne outbreaks. In this study we show that the human secretor FUT2 gene, which codes for an alpha(1,2)-fucosyltransferase synthesizing the H-type 1 antigen in saliva and mucosa, is associated with susceptibility to norovirus infection

Prophylaxis and treatment of bleeding complications in von Willebrand disease type 3.

Treatment of type 3 von Willebrand disease (vWD) relies on infusion with plasma-derived factor concentrates containing von Willebrand factor (vWF). Patients with types 1 and 2 vWD who do not respond satisfactorily after receiving desmopressin need treatment with concentrates. The rationale for long-term prophylaxis in vWD is obvious: prophylaxis has been successfully used in hemophilia, and joint

Measurements of ATP in forest humus

The measurement of ATP as an estimate of microbial biomass C in humus was studied. Three different acid extractants, H2SO4, TCA and H3PO4 were compared, as well as two different buffers, Tris and arsenate. No difference in extraction efficiency was found when the light output was converted to ATP content using internal ATP standards, but the different extraction agents and buffers influenced the l

Do partial and regular migrants differ in their responses to weather?

Partial migration is often considered a transitory stage between migration and residency, and whether partial migrants take weather conditions into account during migration is largely unknown. To assess whether partial migrants differ from regular migrants in their responses to weather, we compared the migratory intensity of a partial migrant, the Blue Tit (Cyanistes caeruleus), with more regular

...han fick det bättre i himmelen

En ny europeisk studie granskar hur allmänheten i sex länder ser på organtransplantationer och postnatala genetiska test. Det rör sig om Cypern, Österrike, Tyskland, Frankrike och Sverige. I undersökningen framkommer att de tillfrågade personernas funderingar följer två övergripande spår: Här finns å ena sidan tankar om den medicinska utvecklingens potential, å andra sidan reflektioner rörande desRecent developments in the field of biomedicine do not only constitute a challenge for the health care systems of modern societies. They also have a profound impact on the core concepts of individual and collective life. The corresponding changes of individual and collective identities take place within the framework of different historically shaped national conditions and traditions. This leads t

Assessing the Functionality of Common Agricultural Policy Payment Instruments in Mixed Forestry-Farming Regions

The EU’s Common Agricultural Policy (CAP) has been broadened over recent decades in response to evolving challenges faced by the EU and its farmers. It now claims to support not only food security and farmers’ incomes, but also transitioning to a green economy, conservation of biodiversity and climate action. We have evaluated to what extent four main types of CAP payment instruments form a cohesi