The matter of white matter in Alzheimer's disease. -On white matter disease from neuropathology and neuroimaging to clinical presentation.
Alzheimer's disease (AD) is the most prevalent type of dementing disorder. The cortical pathology of AD has been recognized for almost a century. In later years, an associated pathological feature of AD has been identified which affects the white matter. This white matter disease (WMD), defined in the microscope, consists of a subtotal tissue loss of the white matter structural components. WMD is
