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Educational gains in cause-specific mortality : Accounting for cognitive ability and family-level confounders using propensity score weighting

A negative educational gradient has been found for many causes of death. This association may be partly explained by confounding factors that affect both educational attainment and mortality. We correct the cause-specific educational gradient for observed individual background and unobserved family factors using an innovative method based on months lost due to a specific cause of death re-weighted

N1-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism

Obesity is a major health problem, and although caloric restriction and exercise are successful strategies to lose adipose tissue in obese individuals, a simultaneous decrease in skeletal muscle mass, negatively effects metabolism and muscle function. To deeper understand molecular events occurring in muscle during weight-loss, we measured the expressional change in human skeletal muscle following

The use of public procurement to incentivize longer lifetime and remanufacturing of computers

Improving the product lifetime of consumer electronics can provide significant environmental benefits. However, there is a tendency among both professional users and consumers to change products, like computers and mobile phones regularly, and as a result their lifetimes become increasingly shorter. With the rise of the Circular Economy, new policies to promote longer product lifetimes have emerge

Circulating Human Basophils and Dendritic Cell Subsets. Aspects of antigen recognition and presentation in type I allergic immune responses

Allergic diseases currently affect a third of the population in the industrialized parts of the world. Despite this, the cellular and molecular mechanisms involved in the induction and activation of allergic diseases are not fully clarified. Dendritic cells (DCs) link the innate and adaptive immunity and play vital roles in protective immunity against pathogens, as well as in inducing tolerance t

The combined effect of wetting ability and durability on outdoor performance of wood : development and verification of a new prediction approach

Comprehensive approaches to predict performance of wood products are requested by international standards, and the first attempts have been made in the frame of European research projects. However, there is still an imminent need for a methodology to implement the durability and moisture performance of wood in an engineering design method and performance classification system. The aim of this stud

Environmental factors in the etiology of type 1 diabetes, celiac disease, and narcolepsy

The etiology of human leukocyte antigen (HLA)-associated organ-specific autoimmune diseases is incomplete. In type 1 diabetes and celiac disease, the strongest associations are with the HLA-DR3-DQ2 and DR4-DQ8 haplotypes, whereas the DQB1*06:02 allele has a strong negative association. In contrast, narcolepsy, especially as recently triggered by the Pandemrix® H1N1 vaccine (GlaxoKlineSmith (GSK),

Prevalence and genetics of immotile-cilia syndrome and left-handedness

Immotile-cilia syndrome is characterized by severe respiratory distress from early infancy, and also often by situs inversus. The first description of the disease was based on just four persons, but reasons were given to suggest that the disorder may not be exceedingly rare. The purpose of the present study was to estimate just how rare or how common it is and to evaluate its association with situ