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Background: Various plasma phosphorylated tau species have been shown to be associated with amyloid-β (Aβ) PET and Tau PET in Alzheimer’s disease (AD), but whether APOE ε4 affects the interaction between glial fibrillary acidic protein (GFAP) and phosphorylated tau (pTau), and whether a three-way interaction exists among APOE ε4, GFAP, and pTau that influences AD progression remain unclear. Method

Popular Abstract in Swedish Diabetes är en grupp sjukdomar som alla kännetecknas av en förhöjd nivå av sockerarten glukos i blodet. Antalet individer som drabbas av diabetes ökar hela tiden, en utveckling som ses över hela världen. Bara i Sverige har drygt 5% av befolkningen diagnosen diabetes, motsvarande 484.400 personer i åldern 20-79 år. Typ 2 diabetes är den vanligaste formen av diabetes, ochThe incidence of diabetes is increasing worldwide, with the most prevalent form being type 2 diabetes. Two fundamental processes contribute to the development of type 2 diabetes: insulin resistance in target organs and insufficient insulin secretion from the pancreatic beta-cells. The aim of this thesis was to explore the role of DNA methylation and common genetic variation on glucose metabolism a

Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING PÅ SVENSKA Kadmium är en giftig metall vilken finns i mat som vi rekommenderas äta mycket av, exempelvis sädesprodukter, grönsaker och skaldjur. Våra matjordar är kontaminerade med kadmium och föroreningen kommer att kvarstå under mycket lång tid framöver. Kadmium skadar framförallt njurarna och skelettet och kan antagligen även orsaAbstract: Cadmium (Cd) is ubiquitous in the environment. Human exposure in non-smokers occurs mainly via intake of healthy food like vegetables, cereals, and shellfish. Adverse health effects on kidney and bone at low-level environmental Cd exposure are well-documented in adults. There is considerable inter-individual variation in both metabolism (toxicokinetics) and toxicity (toxicodynamics) of C

In hydrological models for water resources management and planning, the model output or design quantities are functions of the input data and a number of parameters that are essentially stochastic processes or random variables. The task of uncertainty analysis is to estimate the uncertainty characteristics of the model output in terms of the uncertainties in the input, model parameters and initial

Popular Abstract in Swedish Nästan en miljon nya fall av magsäckscancer diagnostiseras årligen världen över. Även om frekvensen har fallit dramatiskt de senaste åren så är magsäckscancern fortfarande den näst vanligaste orsaken till död i cancer sett ur ett världsperspektiv. Den geografiska variationen av denna cancertyp är anmärkningsvärd med den högsta förekomsten i asiatiska länder såsom Japan,

Under de senaste 10 åren har ökningen av export från EU av farligt och ”ofarligt” avfall varit betydande. Rapporter visar att en övervägande del av EU:s el-avfall och elektroniska avfall exporteras till Asien och Afrika. ”Ofarligt” avfall, såsom plast och papper, transporteras främst till Asien och i synnerhet till Kina. I dessa länder finns emellertid ofta inte kapaciteten och tekniken att hanter

Sri Lanka is a small island in the Indian Ocean with a population of 19.5 million. UN (2005), &lt&semichttp://news.bbc.co.uk/2/hi/south_asia/country_profiles/1168427.stm&gt&semic, visited on 13th December 2005. History witnesseth of the Yakka &amp&semic Naga tribes ('Gothras') and the Nittevo The Nittevo are said to have been a dwarfish race of men who lived in the

Ett för miljörätten tidigt uppkommet styrmedel som idag hyllas är miljökonsekvensbeskrivningen. Flertalet länder har infört MKB i sin lagstiftning och det har utformats internationella bestämmelser för gränsöverskridande miljöpåverkan. Även inom klimatregimen finns reglering för projekt i CDM systemet. I detta arbete har Sveriges CDM projekt studerats för att fastställa syfte med MKB inom CDM systA respected and early invention among the means of control in environmental law is the impact assessment. Numerous countries have implemented EIA in their national legislation and international treaties regulates transboundary environmental impacts. UNFCCC also contains EIA regulations for projects within the clean development mechanism. In this study Swedish projects are examined to establish the

Spatial downscaling is an effective way to obtain precipitation with sufficient spatial details. The performance of downscaling is typically determined by the empirical statistical relationships between precipitation and the used auxiliary variables. In this study, we conducted a comprehensive comparison of five empirical statistical methods for spatial downscaling of GPM IMERG V06B monthly and an

This Ph.D. submission deals with contemporary demonstration culture and political activism, seen as performance through performance. It consists of both a practical and a theoretical part. These are intertwined on various levels of the project. My submission, however, is made up of the two following parts: 1: A textual part, divided into 8 parts. Each part contains a script, an analysis and a nu

Based on trend, cross-cutting relationships and U-Pb dating, Precambrian mafic dykes in the Singhbhum craton, earlier collectively identified as ‘Newer Dolerite Swarm’ have been separated into seven distinct swarms, which are thought to be the plumbing systems for Large Igneous Provinces (LIPs). These Singhbhum swarms range in age from ∼2.80 Ga to ∼1.76 Ga, and include the ∼2.80 Ga NE-SW trending

Version 3 av ecoinvent är den första databasen att erbjuda möjligheten att koppla samman livscykelinventeringar (LCI) utefter olika länkningsalgoritmer. Genom dessa länkningsalgoritmer tar ecoinvent nu fram bakgrundslivscykelinventeringar med både medeldata och långsiktig marginaldata (t.ex. över elmarknader i olika länder). Idealt sett representerar långsiktig marginaldata över elmarknader den ytVersion 3 of the ecoinvent database is the first background database to offer the possibility to link life cycle inventories (LCI) according to different linking algorithms. Using those algorithms, ecoinvent now provides both average and long-term, marginal background LCI data, (e.g. for electricity markets for different countries). Long-term, marginal data for electricity markets ideally represen

Eddy covariance (EC) measurements are often used to validate net ecosystem productivity (NEP) estimated from satellite remote sensing data and biogeochemical models. However, EC measurements represent an integrated flux over their footprint area, which usually differs from respective model grids or remote sensing pixels. Quantifying the uncertainties of scale mismatch associated with gridded flux

Background: The frequent emergence of the re-positive patients with COVID-19 is a potential threat worldwide. This study aimed to describe data from admission to follow-up for patients with COVID-19 and analyze the possible causes for re-positive nucleic acid tests to provide more scientific basis for reducing the numbers of re-positive patients after discharge. Methods: We retrospectively recorde

Between 15 and 27kyrb2k (thousands of years before 2000CE) during the last glacial, Greenland experienced a prolonged cold stadial phase, interrupted by two short-lived warm interstadials. Greenland ice-core calcium data show two periods, preceding the interstadials, of anomalously high atmospheric dust loading, the origin of which is not well understood. At approximately the same time as the Gree

Popular Abstract in Swedish Avhandlingen diskuterar Sociologins position i debatten kring artificiell intelligens, d.v.s sådan AI som kan skapa kunskap på egen hand. Det påpekas att sociologin behöver göra en åtskillnad mellan två sätt att skapa AI system: Symbolisk AI (eller Klassisk AI) och Distribuerad AI – DAI. Den sociologiska litteraturen visar en i stort kritisk attityd till symbolisk AI viThis dissertation is concerned with Sociology’s stance in the debate on Strong Artificial Intelligence, i.e. such AI that is able to shape new knowledge without human interference. There is a need for sociologists to realize the difference between two approaches to constructing AI systems: Symbolic AI (or Classic AI) and Distributed AI – DAI. Sociological literature shows a largely critical attitu

4th International Workshop on the Sharing Economy THE INTERNATIONAL INSTITUTE FOR INDUSTRIAL ENVIRONMENTAL ECONOMICS AT LUND UNIVERSITY LUND, SWEDEN, 15-16 JUNE 2017 Nomen Nescio, Titulus etc SPONSORS: THE INTERNATIONAL INSTITUTE FOR INDUSTRIAL ENVIRON- MENTAL ECONOMICS, AT LUND UNIVERSITY THE DEPARTMENT OF URBAN PLANNING AND ENVIRONMENT AT KTH, ROYAL INSTITUTE OF TECHNOLOGY 4th International Work

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/4iwse_final_31_oct._2016.pdf - 2026-01-11