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Lipolysis is an important metabolic pathway controlling energy homeostasis through degradation of triglycerides stored in lipid droplets and release of fatty acids. Lipid droplets of mammalian cells are coated with one or more members of the PAT protein family, which serve important functions in regulating lipolysis. In this study, we investigate the mechanisms by which PAT family members, perilip

As a global society we are entering an era where land areas and land-based resources are coming to the fore once again for capital accumulation and economic growth, for the first time since the end of the 18th century when Malthus forecasted a contradiction between population growth and agricultural output. That constraint on economic growth, imposed by limited land areas, was overcome by the comb

Heparan sulfate 3-O-sulfotransferase transfers sulfate to the 3-OH position of a glucosamine residue of heparan sulfate (HS) to form 3-O-sulfated HS. The 3-O-sulfated glucosamine residue contributes to two important biological functions of HS: binding to antithrombin and thereby carrying anticoagulant activity, and binding to herpes simplex viral envelope glycoprotein D to serve as an entry recept

The nexus of population growth and changing diets has increased the demands placed on agriculture to supply food for human consumption, animal feed and fuel. Rising incomes lead to dietary changes, from staple crops, towards commodities with greater land requirements, e.g. meat and dairy products. Despite yield improvements partially offsetting increases in demand, agricultural land has still been

The accumulation of empirical evidence that outward-oriented developing countries have generally performed better than inward-oriented ones in terms of growth, industrialisation, job creation and other macroeconomic indicators provides an essential lesson for both policy-makers and development economists worldwide. The acknowledged importance of trade and non-traditional exports for development an

Palaeomagnetic data are used to study the configurations of continents during the Proterozoic. Applying stringent reliability criteria, the positions of the continents at 12 times in the 2.45- to 1.00-Ga period have been constructed. The continents lie predominantly in low to intermediate latitudes. The sedimentological indicators of palaeoclimate are generally consistent with the palaeomagnetic l

What do we gain from labeling certain norms of social organization law? This question provides the backdrop against which this chapter will examine the works of Leon Petrażycki and Eugen Ehrlich, two of the founders of legal sociology who devised concepts of law broader than state law. In the course of this examination we shall also assess the relevance of Petrażycki’s 'intuitive law' and Ehrlich’

Over the years, the field of landslide disaster research has amassed a wealth of data and specialized knowledge. However, these resources originate from a wide array of sources and often feature complex data structures, highlighting a persistent lack of methods to integrate multi-source, heterogeneous data. Traditional landslide monitoring methods typically focus on singular monitoring targets and

Hydrological processes in a watershed consist of multiple sub-processes (such as plant growth, evapotranspiration, water yield, and soil–water balance) that have complex interactions. The common practice of calibrating hydrological models against only a single variable (e.g., streamflow) can lead to parameter uncertainty (also known as equifinality), resulting in significant uncertainties in the r

This thesis challenges the prevailing firm-consumer/customer-centric and dyadic perspective that prevails within the brand equity literature, which is based on a linear, straightforward stimulus-response approach to the creation of brand value. Leaning on the literature on interorganisational relationships, stakeholder theory, market emergence/market driving, and firm internationalisation, which s

In recent years, an increasing number of ecosystems are threatened by seasonal flooding, changing non-flooded shoreland (NF) into seasonally flooded wetland (SF), but the consequences of this hydrological change for soil organic carbon (SOC) dynamics remain unknown. In this study, we investigated how the SOC content was determined by flooding duration and soil physicochemical variables in adjacent

INTRODUCTION: Reporting of sex and gender analysis in medical research has been shown to improve quality of the science and ensures findings are applicable to women and men. There is conflicting evidence on whether efforts by funding agencies and medical journals to encourage reporting of sex and gender analysis has resulted in tangible improvements. This study mapped the inclusion of sex and gend

Solceller – en miljövänlig energikälla? Miljöförstöring i form av växthusgasutsläpp är en gigantisk utmaning som mänskligheten står inför och vi måste agera NU! Solceller innebär en fantastisk möjlighet att utvinna stora mängder “ren” energi från solen. Men hur miljövänliga är egentligen solceller och är det ett effektivt alternativ i Sverige? Varje timme träffas Jorden av tillräckligt mycket eClimate change is one of the greatest environmental challenges at the present time and is currently an issue affecting the entire global population. Alternative renewable energy sources are vital to be able to deal with this challenge. Solar energy is one of the most promising renewable energy sources and is therefore also one of the fastest growing industries in this field. However, solar energy