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Business Model Design - A Matter of Perspective?

The shift from internal combustion to electric engines is currently transforming the automotive industry. Yet, the business model path forward for electric vehicles (EVs) is still uncertain, as the perspectives of different industry actors, especially incumbents and new entrants deviate. The understanding of varying views regarding business model design thus needs to be intensified. Therefore, the

The classification of the Tibetans as a people with the right to self-determination

Tibet, the land of snows, has always in many people's minds been a mystical land with a deeply rooted religion and a people living in harmony with themselves and nature. Once one step outside this picture, the confrontation with the reality of the enormous problems and suffering that the Tibetan people had gone through during the last fifty years becomes almost to painful. Much of the violatio

Regional trends and drivers of the global methane budget

The ongoing development of the Global Carbon Project (GCP) global methane (CH4) budget shows a continuation of increasing CH4 emissions and CH4 accumulation in the atmosphere during 2000–2017. Here, we decompose the global budget into 19 regions (18 land and 1 oceanic) and five key source sectors to spatially attribute the observed global trends. A comparison of top-down (TD) (atmospheric and tran

Development and validation of a machine learning-based model to predict isolated post-challenge hyperglycemia in middle-aged and elder adults : Analysis from a multicentric study

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

Combination of Lyapunov Functions and Density Functions for Stability of Rotational Motion

Lyapunov methods and density functions provide dual characterizations of the solutions of a nonlinear dynamic system. This work exploits the idea of combining both techniques, to yield stability results that are valid for almost all the solutions of the system. Based on the combination of Lyapunov and density functions, analysis methods are proposed for the derivation of almost input-to-state sta

Flood analysis and protection system : Application to The Hongru River

The definition of a decision support system(DSS) may be : human-computer interactive software system to solve semi-structured decisional problems for decisional makers with data utilizing, information management, knowledge, as well as model techniques. DSS only provide supporting information about making decision for the decision maker without stipulate the decision itself. Decision is made by hum

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Objective To explore the feasibility of retroviral-mediated Flt 3 ligand (FL) and thrombopoietin (Tpo) genes transferred into and expressed in a bone marrow stromal cell line HFCL by internal ribosome entry site(IRES)sequence. Methods IRES sequence, FL and Tpo cDNA were recombined with retroviral vector pLXSN by gene recombination technology. The recombinant plasmid was transferred into retrovirus