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The Last Termination in the South Indian Ocean: A unique terrestrial record from Kerguelen Islands (49 degrees S) situated within the Southern Hemisphere westerly belt
The awareness of the significance of the Southern Ocean in the Earth's climate system has become increasingly obvious. The deglacial atmospheric CO2 rise during warming periods in Antarctica has been attributed to CO2 ventilation from the deep ocean caused by enhanced upwelling around the Antarctic Divergence. It has been hypothesized that, more intense Southern Hemisphere westerly winds aligned w
Alcohol abuse in cancer patients: a shadow side in the oncological field and research.
This article aims to foreground alcohol abuse by cancer patients and explore how alcohol abuse functions as a biographic master motive and at the same time is a shadow side in the oncological field and research. The research is based on a single case study which draws on empirical material from interviews, field notes and staff policy, with analysis using Bourdieu's concepts of trajectory of life
Climate variability and glacial processes in eastern Iceland during the past 700 years based on varved lake sediments
Properties of varved sediments from Lake Logurinn in eastern Iceland and their link to climate and glacial processes of Eyjabakkajokull, an outlet glacier of the Vatnajokull icecap, were examined. A varve chronology, which covers the period AD 1262-2005, was constructed from visual observations, high-resolution images, X-ray density and geochemical properties determined from X-radiography and X-ra
Associations of invasive alien species and other threats to IUCN Red List species (Chordata: vertebrates)
Apart from acting synergistically or additively, threats to species may be associated or disassociated. Here we link global data on threatened Chordata species, mainly birds, mammals, and amphibians, with a probabilistic methodology to test whether the impact from invasive alien species co-occurs purely randomly, associated, or disassociated with impact from nine other major threats to biodiversit
Differentiated Knowledge Bases and the Nature of Innovation Networks
It is argued in this paper that the nature of innovation networks can vary substantially with regard to the type of knowledge that is critical for innovation. Subject to the knowledge base of an industry, networks between companies can differ in various aspects, such as their geographical configuration, their structure, the type of actors holding a strategic position and the type of relations betw
Pore size assessment based on wall collision broadening of spectral lines of confined gas: experiments on strongly scattering nanoporous ceramics with fine-tuned pore sizes
Wall collision broadening of absorption lines of gases confined in porous media is a recently opened domain of high-resolution spectroscopy. Here, we present an experimental investigation of its application for pore size assessment. We report on the manufacturing of nanoporous zirconia ceramics with well-defined pore sizes fine-tuned from 50 to 150 nm. The resulting pore structure is characterized
Prevention and treatment of colon cancer by peroral administration of HAMLET (human α-lactalbumin made lethal to tumour cells).
BACKGROUND: Most colon cancers start with dysregulated Wnt/β-catenin signalling and remain a major therapeutic challenge. Examining whether HAMLET (human α-lactalbumin made lethal to tumour cells) may be used for colon cancer treatment is logical, based on the properties of the complex and its biological context. OBJECTIVE: To investigate if HAMLET can be used for colon cancer treatment and preven
Ecological-Level Associations Between Highly Processed Food Intakes and Plasma Phospholipid Elaidic Acid Concentrations: Results From a Cross-Sectional Study Within the European Prospective Investigation Into Cancer and Nutrition (EPIC)
Elaidic acid is the main unnatural trans fatty acid isomer occurring during partial hydrogenation of vegetable oils used as ingredients for the formulation of processed foods. The main objective is to assess associations between processed food intakes and plasma phospholipid elaidic acid concentrations within the European Prospective Investigation into Cancer and Nutrition study. A cross-sectional
An optogenetic approach in epilepsy.
Optogenetic tools comprise a variety of different light-sensitive proteins from single-cell organisms that can be expressed in mammalian neurons and effectively control their excitability. Two main classes of optogenetic tools allow to either depolarize or hyperpolarize, and respectively generate or inhibit action potentials in selective populations of neurons. This opens unprecedented possibiliti
Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate
Recent studies have identified a number of transcriptional regulators, including E2A, early B-cell factor 1 (EBF1), FOXO1, and paired box gene 5 (PAX5), that promote early B-cell development. However, how this ensemble of regulators mechanistically promotes B-cell fate remains poorly understood. Here we demonstrate that B-cell development in FOXO1-deficient mice is arrested in the common lymphoid
Performing work: The drama of everyday working life
Abstract in UndeterminedIn this article, a perspective on work time patterns is outlined; a perspective that emphasizes the importance of observing how work time is subject not only to task and contract agreements but also to social norms and individual needs to express identity. The article takes its starting point in Goffman’s dramaturgic approach. From this perspective, the workplace is viewed
IL-17A is Elevated in End-stage COPD and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis.
End-stage chronic obstructive pulmonary disease (COPD) is associated with an accumulation of pulmonary lymphoid follicles. Interleukin (IL)-17A is implicated in COPD and pulmonary lymphoid neogenesis in response to microbial stimuli. We hypothesized that IL-17A is increased in peripheral lung tissue during end-stage COPD and also directly contributes to cigarette smoke-induced lymphoid neogenesis.
Assessment of legal framework for corporate environmental behaviour and perceptions of residents in mining communities in Ghana
The paper examines the laws and policies that regulate corporate environmental practices in Ghana, with an emphasis on mining. In particular, the analysis of the legal and regulatory framework examines the extent to which it meets international best practices and standards of corporate conduct and the extent to which self-regulatory mechanisms are accommodated under the framework. This was accompl
Dietary intake of iron, heme-iron and magnesium and pancreatic cancer risk in the European prospective investigation into cancer and nutrition cohort
Several studies support a protective effect of dietary magnesium against type 2 diabetes, but a harmful effect for iron. As diabetes has been linked to pancreatic cancer, intake of these nutrients may be also associated with this cancer. We examined the association between dietary intake of magnesium, total iron and heme-iron and pancreatic cancer risk in the European Prospective Investigation int
The Moral Foundations taxonomy: Structural validity and relation to political ideology in Sweden
Although Moral Foundations Theory claims that the foundations of morality are universal, there are still few studies addressing it through non-English measures. In the current research, 540 persons filled out a Swedish translation of the Moral Foundations Questionnaire, and 332 of them filled out political attitude measures. Confirmatory factor analyses suggested that the fit of the five-factor mo
Tiger talk and candy king: marketing of unhealthy food and beverages to Swedish children
An Exploratory Study of Rework Causality in Uganda
Review Article of Self-Projection : The Director's Image in Art Cinema
Retailers' management of CSR in their supplier relationships - does practice follow best practices?
The aim of this study is to further explore (a) the extent to which retailers deploy corporate social responsibility (CSR) best practices to ensure social and environmental sustainability in international supplier relationships and (b) the association between firm characteristics and the retailers’ CSR activities in the supply chain. As a first step, the study identifies eight best practices based