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Complete Topological Mapping of a Cellular Protein Interactome Reveals Bow-Tie Motifs as Ubiquitous Connectors of Protein Complexes

The network topology of a protein interactome is shaped by the function of each protein, making it a resource of functional knowledge in tissues and in single cells. Today, this resource is underused, as complete network topology characterization has proved difficult for large protein interactomes. We apply a matrix visualization and decoding approach to a physical protein interactome of a dendrit

No more water, but fire next time : The conflict between environmental aims and social claims in Louisiana's post-Katrina coastal planning

There are two levels to this thesis, the examination of the particular case and the exposition of the general approach. The case the thesis deals with is Louisiana’s coastal land-loss crisis and what can and should be done about it. I examine the current approach to coastal protection and restoration in the state of Louisiana, drawing on different economic theories of sustainable development and c

Mixed airway and pulmonary parenchymal disease in patients with primary Sjögren's Syndrome - a six-year follow-up

OBJECTIVE: To assess pulmonary function and Chronic Obstructive Pulmonary Disease (COPD) development over time in patients with primary Sjögren's Syndrome (pSS) and the association between pulmonary function, radiographic findings, respiratory symptoms and clinical features of pSS, taking cigarette consumption into account.METHODS: Forty patients with pSS (mean age 66 yrs, range 42-81 yrs, 39 wome

Formation and composition of the UTLS aerosol

Stratospheric aerosol has long been seen as a pure mixture of sulfuric acid and water. Recent measurements, however, found a considerable carbonaceous fraction extending at least 8 km into the stratosphere. This fraction affects the aerosol optical depth (AOD) and the radiative properties, and hence the radiative forcing and climate impact of the stratospheric aerosol. Here we present an investiga

Innovation Region Sweden

Älska Skog educational competition (Gothenburg, Sweden)Gothenburg-based educational institute Universeum is running annual design competitions on forest topics for primary school pupils, starting in 2016. Based on various activities in which pupils gain knowledge about forest-related challenges and opportunities as well as forestry, they would design plans to deal with those problems. After a firs

Value of information-based inspection, monitoring, and damage detection system planning

Inspections, Structural Health Monitoring (SHM), and Damage Detection System (DDS) are integral parts of structural integrity management (SIM) to ensure the structural performance and the required safety. This paper describes novel approaches on how the outcomes of Structural Health Monitoring (SHM) can be modeled, predicted, and combined with inspection planning in the frame of pre-posterior deci

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Artiklen sætter fokus på en nylig materiel vending i litteraturen; en ny opmærksomhed mod litteraturens materielle diensioner som præger både litteraturkritikken olitteraturen selv. Med udgangspunkt i litterære materialitetsteorier af bl.a. Bill Brown og N. Katherine Hayles undersøger jeg, hvordan denne tendens kommer til udtryk i to værker, Anne Carsons Nox og Oscar K.s Af Olafur Kjartanssons opt

Intermedial Strategies of Memory in Contemporary Novels

In her article "Intermedial Strategies and Memory in Contemporary Novels" Sara Tanderup discusses a tendency in contemporary literature towards combining intermedial experiments with a thematic preoccupation with memory and trauma. Analyzing selected works by Steven Hall, Jonathan Safran Foer, and Judd Morrissey and drawing on the theoretical perspectives of N. Katherine Hayles (media studies) and

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Recently, several literary works have appeared which use formal experiments and intermedial strategies to thematize memory and history. Authors such as Alexander Kluge, W.G. Sebald, Daniel Mendelsohn, Monica Maron, Jonathan Safran Foer, Don DeLillo and Aleksandar Hemon include other, primarily visual, media such as film, photographs and drawings, in their works while dealing with historical events

Cities and Consumption - Urban Sustainability and the Sharing Economy : Course Guide

How can we govern consumption and the sharing economy in our cities? This course explores cities, consumption and the sharing economy in Europe and around the world. We connect together the key themes of the sharing economy, cities, governance, consumption and urban sustainability. We explore how the sharing economy can contribute to increasing social, environmental and economic sustainability. An

A Model for Evaluating Therapeutic Response of Combined Cancer Treatment Modalities : Applied to Treatment of Subcutaneously Implanted Brain Tumors (N32 and N29) in Fischer Rats with Pulsed Electric Fields (PEF) and 60Co-gamma Radiation (RT)

The aim of the present study is to develop a mathematical model for evaluating therapeutic response of combined treatment modalities. The study was performed in rats of the Fischer-344 strain with rat glioma N32 or N29 tumors implanted subcutaneously on the thigh of the hind leg. Pulsed electric fields, PEF, with 16 exponentially decaying pulses with a maximum electric field strength of 140 V/mm a

Quantitative study of flow dependence in NMR images at low flow velocities

A basic theoretical model that describes the effects of flow in and out of the imaging plane in nuclear magnetic resonance (NMR) images, obtained with the standard pulse sequences single spin echo, multiple spin echo, and inversion recovery, is presented. Theoretically calculated signal values are compared with experimental results obtained from single-slice images of a flow phantom for variable f

Liver blood flow studies during local hyperthermia. An experimental study in rats

Regional blood flow in rat liver and in inoculated liver tumors was studied before, during and after local hyperthermia treatment at 42.0°C for one hour. Hyperthermia was induced by microwave irradiation of the central liver lobe. The method used for blood flow studies was the clearance of Xenon-133 following portal and intraparenchymal injection. The wash-out curves were analyzed by using a bi-ex

Particle sizing and biokinetics of interstitiallymphoscintigraphic agents

The biokinetics of inert lymphoscintigraphic agentsstrongly depends on their particle size. Different techniques for characterization of colloids are discussed. Experiments have been performed on eight different colloids. The particle size has been investigated with scanning electron microscopy. Activity distributions have been obtained with ultrafiltration and gel-column scanning technique. The c