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On the Thermodynamic Solvation of Biomolecules in Solution

The topic solvation thermodynamics is an important aspect of chemistry, dealing with the effects introduced by solvents onto solutes. In particular, biological systems are highly heterogeneous in their choice of solvent typically characterized by either being in a polar or non-polar environment. For example, the cytoplasm of cells constituting the internal environment of cells is an aqueous solven

Strävan efter självständighet : Inre och yttre krav på en idéburen välfärdsaktör

En ideal bild av en aktör visar på självständighet och kontroll. För organisationer i det civila samhället är frågorna om beroende och oberoende ständigt brännande. Ett nytt krav på en ”effektrapport” väcker mycken tankemöda. Ska den idéburna verksamheten börja ”mäta en massa saker” i stället för att ”jobba, jobba!”?Kapitlet redovisar en studie som sträcker sig över fem år om införandet av en redo

COVID-19 in Pregnancy and Early Childhood (COPE) : study protocol for a prospective, multicentre biobank, survey and database cohort study

INTRODUCTION: There is limited knowledge on how the SARS-CoV-2 affects pregnancy outcomes. Studies investigating the impact of COVID-19 in early pregnancy are scarce and information on long-term follow-up is lacking.The purpose of this project is to study the impact of COVID-19 on pregnancy outcomes and long-term maternal and child health by: (1) establishing a database and biobank from pregnant w

On user effects of a low-profile MIMO terminal antenna with wideband multimodal excitation

When in use, a mobile terminal is often held in the hand by the user. However, conventionally terminal antennas are only evaluated in free space, disregarding the effects of user interaction. In this paper, the performance of a low-profile twoport multiple-input multiple-output (MIMO) antenna that offers wide symmetrical bandwidth and low correlation in free space is investigated in presence of a

Association of managerial position with cardiovascular risk factors : A fixed-effects analysis for japanese employees

Objectives Although higher occupational classes have been reported to be associated with better health, researchers do not fully understand whether such associations derive from the position or individual characteristics of the person in that position. We examined the association between being a manager and cardiovascular disease (CVD) risk factors using unique panel data in Japan that annually ob

Association of Sleep Duration with All- And Major-Cause Mortality among Adults in Japan, China, Singapore, and Korea

Importance: The association between long sleep duration and mortality appears stronger in East Asian populations than in North American or European populations. Objectives: To assess the sex-specific association between sleep duration and all-cause and major-cause mortality in a pooled longitudinal cohort and to stratify the association by age and body mass index. Design, Setting, and Participants

Citizenship Denied, Deferred and Assumed : A Legal History of Racialized Citizenship in Myanmar

Since the late colonial period, Myanmar has experienced heated debates over notions of belonging, including belonging as inscribed through citizenship status. At independence, Myanmar opted for a hybrid citizenship regime that allowed for paths to citizenship based on both jus sanguinis and jus soli principles, as well as a liberal naturalization policy. However, a new citizenship law passed in 19

Myanmar's Hidden-in-plain-sight social infrastructure : Nalehmu through multiple ruptures

This article examines nalehmu, a set of informal relational practices for negotiating power across scales which have facilitated access and enforced accountability through mutually recognized norms and social sanctions in Myanmar. Like Asef Bayat’s “quiet encroachment” in the Middle East, nalehmu is Myanmar’s discreet and prolonged practice of agency that has enabled ordinary people to survive and

Models of natural pest control : Towards predictions across agricultural landscapes

Natural control of invertebrate crop pests has the potential to complement or replace conventional insecticide-based practices, but its mainstream application is hampered by predictive unreliability across agroecosystems. Inconsistent responses of natural pest control to changes in landscape characteristics have been attributed to ecological complexity and system-specific conditions. Here, we revi

Male Sex Work in Sweden: Criminalization of the Client

The chapter engages with the so-called Swedish Model in the country of its invention: Sweden. First, it examines feminist thought that has supported the implementation of this legislation. Next, it looks at the effects of this law according to 12 key informants and 25 male sex workers. Ultimately, the criminalization of sex work in Sweden is so focused on women selling sex to men that police and p

Unpicking the Sex Work Conundrum

What is sex work? I have decided to start this short contribution with a question, which I think the reader should answer before continuing. So what is sex work? Is it a legitimate form of work or is it a job whose only characteristics are exploitation, harassment, and coercion? Also, can a person (woman or man) freely decide to be a sex worker or is it impossible to engage in such profession with

Helical tomotherapy for total marrow and total skin irradiation : Optimisation, verification, and clinical results

In modern cancer therapy, radiotherapy (RT) is a vital part of most treatments. Most RT treatments in Sweden are performed using intensity-modulated radiotherapy (IMRT) with fixed or dynamic arc delivery. The dose gradients outside the target are steep, the margins are small, and the treatment delivery is complicated. Complicated treatments increase the requirement for control of the uncertaintiesIn modern cancer therapy, radiotherapy (RT) is a vital part of most treatments. Most RT treatments in Sweden are performed using intensity-modulated radiotherapy (IMRT) with fixed or dynamic arc delivery. The dose gradients outside the target are steep, the margins are small, and the treatment delivery is complicated. Complicated treatments increase the requirement for control of the uncertainties

A drug screen with approved compounds identifies amlexanox as a novel Wnt/β-catenin activator inducing lung epithelial organoid formation

Background and Purpose: Emphysema is an incurable disease characterized by loss of lung tissue leading to impaired gas exchange. Wnt/β-catenin signalling is reduced in emphysema, and exogenous activation of the pathway in experimental models in vivo and in human ex vivo lung tissue improves lung function and structure. We sought to identify a pharmaceutical able to activate Wnt/β-catenin signallin

Dopaminergic and serotonergic alterations in plasma in three groups of dystonia patients

Introduction: In dystonia, dopaminergic alterations are considered to be responsible for the motor symptoms. Recent attention for the highly prevalent non-motor symptoms suggest also a role for serotonin in the pathophysiology. In this study we investigated the dopaminergic, serotonergic and noradrenergic metabolism in blood samples of dystonia patients and its relation with (non-)motor manifestat