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Decreasing incidence of major amputation in diabetic patients: a consequence of a multidisciplinary foot care team approach?

The purpose of this retrospective study was to evaluate the changes in diabetes-related lower extremity amputations following the implementation of a multidisciplinary programme for prevention and treatment of diabetic foot ulcers in a 0.2 million population with a 2.4% prevalence of diabetes. All diabetes-related primary amputations from toe to hip from 1 January 1982 to 31 December 1993 were inc

Differentiated Knowledge Bases and Varieties of Regional Innovation Systems

This article introduces a theoretical and analytical framework for discussing regional development and regional advantage with reference to a regional innovation system strategy. It uses the differentiated knowledge base approach to transcend the traditional codified-tacit dichotomy of knowledge, and for providing a trans-sectoral understanding of economic activities. Different regional innovation

Nuclear Structure far off Stability - RISING Campaigns

Nuclear structure studies at CST attracted recently increased interest for the results of present activities as well as for the future project FAIR. A broad range of physics phenomena can be addressed by high-resolution in-beam gamma-ray spectroscopy experiments with radioactive beams offered within the Rare Isotopes Spectroscopic INvestigation at GSI (RISING) project. It combined the EUROBALL Ge-

Huntington's disease: a synaptopathy?

Huntington's disease (HD) is caused by a polyglutamine expansion in the protein huntingtin. In its terminal stage, HD is characterized by widespread neuronal death in the neocortex and the striatum. Classically, this neuronal death has been thought to underlie most of the symptoms of the disease. Accumulating evidence suggests, however, that cellular dysfunction is important in the pathogenesis of

Nyquist's Contributions to Control and Communication

Slides from two lectures given at the commemoration of the Nyquist Hall at Karlstad Institute of Technology. The first lecture presents Nyquist's stability criterion and discusses its consequences for the field of Automatic Control. The second lecture (in Swedish) gives a shorter but broader presentation of Nyquist's contributions to communication and control.

Lipoprotein production by the heart: a novel pathway of triglyceride export from cardiomyocytes

The current knowledge on lipoprotein secretion from the heart is examined in this article. The ability of cells to secrete apolipoprotein B (apo-B) containing lipoproteins depends on expression of the apo-B and microsomal triglyceride transfer protein (MTP) genes. Initially, it was shown that both genes are expressed in cardiac myocytes of mice and humans. Electron microscopy of human cardiac myoc

Whitepaper: S88 for Beginners

Are you interested in or curious about Batch Control, ISA S88, and/or Plant Automation in general, then this whitepaper is for you. In the following three pages you will learn the basics about Batch Control and ISA S88 and you will understand how you can benefit from knowing them. For a deeper understanding I recommend you to read the other whitepapers in this series as well as reading the ISA S8

The Department of English in Lund : Working Papers in Linguistics Vol. 3

The Department of English in Lund: Working Papers in Linguistics is an annual volume produced by the English Department at Lund University in Sweden. Its main aim is to publicize research being carried out by staff and post-graduate students in the department, but we are also pleased to include contributions from members of neighbouring departments and universities. The contributions in volume 3

A computational study of an HCCI engine with direct injection during gas exchange

We present a new probability density function (PDF)-based computational model to simulate a homogeneous charge compression ignition (HCCI) engine with direct injection (DI) during gas exchange. This stochastic reactor model (SRM) accounts for the engine breathing process in addition to the closed-volume HCCI engine operation. A weighted-particle Monte Carlo method is used to solve the resulting PD