The aim of this study was to evaluate whether biomarkers of environmental tobacco smoke exposure [i.e, 4-aminobiphenyl-hemoglobin (4-ABP-Hb) adducts] were predictive of the risk of tobacco-related cancers and diseases. We did a case control study nested within the European Prospective Investigation into Cancer and Nutrition, involving 190 controls and 149 cases (incident cancer of the lung, bladde

Intravenous infusions of 750 and 1000 ml 2.2% sodium citrate were given over a 60 min period to 17 pigs to study its effect on aortic pressure, electrocardiogram, ionised calcium, and citrate clearance. In group 1 (seven pigs) the animals did not receive calcium and the median survival time was 30 min (range 20-70 min). In groups 2 and 3 (five in each group) the pigs were treated with calcium chlo

Epitopes found on Mucin-1 are differentially expressed on tumour versus normal tissue. Such epitopes have also been shown to have a potential in immunotherapy and tumour detection. The major epitope explored in this context is located within the variable number of tandem repeats. It has however recently been demonstrated that this epitope exists in several sequence variants. The standard sequence

The mixed-valence dinuclear ruthenium complex [Ru2(bpmp)(-OAc)2]2+ (where bpmp is the phenolate anion of 2,6-bis[bis(2-pyridylmethyl) aminomethyl]-4-methylphenol, H-bpmp) has been studied by UV-Vis-NIR, IR, and EPR spectroscopic and electrochemical techniques. The Ru2II,III complex undergoes reversible one-electron reduction (E1/2 = -0.61 V vs Fc+/0) and oxidation (E1/2 = 0.09 V vs Fc+/0), resulti

The Rydberg formula is emblematic of atomic spectroscopy. We review here the personal background, research accomplishments, and academic career of its discoverer, Janne Rydberg. Although his formula is often introduced as a generalization of the hydrogenic Balmer formula, Rydberg’s work was independent of Balmer’s, and displayed great ingenuity and a rare ability to recognize hidden patterns in co

The thesis presents the author s research on numerical methods for Com-putational Aeroacoustics and the development of computational tools with direct applicability in industry. The designers in the gas-turbine industry, require accurate methods for predicting the onset and the frequencies of dangerous (pressure) oscillations, like the ones which typically occur in Lean Premixed Pre-vaporized (LPP

On 7 December 1975 Indonesian troops invaded the former Portuguese colony of East Timor, which had unilaterally declared itself independent on 28 November the same year. The immediate background to the Indonesian invasion of East Timor was that the old regime in Portugal was overthrown in April 1974, resulting in a decolonisation programme for Portugal's colonies. Immediately after the invasion In

The potential and limitations of the Homogeneous Charge Compression Ignition (HCCI) engine concept has been experimentally investigated. The operation range, in terms of usable air/fuel ratio and engine load, and the emission characteristics have been studied. An 1.6 litre single cylinder engine based on a heavy duty six cylinder Volvo, was used for the tests. As follows the experimental work was

Synaptotagmins (Syts) are involved in Ca2+-dependent insulin release. However, which Syt isoform is functional in primary beta-cells remains unknown. We demonstrate by electron microscopy of pancreatic islets, the association of Syt 9 with insulin granules. Silencing of Syt 9 by RNA interference adenovirus in islet cells had no effect on the expression of Syt 5, Syt 7 and Syt 3 isoforms. The latte

The CHIC Collaboration has performed a series of simultaneous pp, np and nn fermion interferometry experiments in order to study the space-time evolution of the emission sources in intermediate energy heavy ion reactions. Furthermore, when correlations of non-identical particles are available, additional model independent information on the emission chronology of the particles is obtained. In this

Methods of analysing and interpreting two-dimensional velocity field data in order to understand the scales of turbulence of bubbly two-phase flow were developed. Reynolds decomposition and large eddy simulation (LES) decompositions (low-pass filtering), in conjunction with proper orthogonal decomposition (POD) energy spectra analysis, as well as adjusted convective decomposition (constant convect

Eko-doppler med vävnadsdoppler ger säkrare hjärtsviktsdiagnostik och kan utföras vid sängkanten. Vävnadsdoppler har givit ny insikt i patofysiologin vid hjärtsvikt. Färgvävnadsdoppler är grunden för parametriska hjärtbilder och kan användas för icke-invasiv skattning av fyllnadstryck. Systolisk och diastolisk funktion är alltid kopplade. Man bör därför använda begreppen »svikt med normal EF« respe