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Selective reduction of nitroaromatic compounds on silver nanoparticles by visible light

For the first time, we report experimentally and theoretically that nitroaromatic compounds, 2,4-dinitrobenzenethiol and 4-chloro-2-nitrobenzenethiol, on silver sols can be selectively reduced to 2-amino-4-nitrobenzenethiol and 2-amino-4-chlorobenzenethiol simply by irradiating with a visible light in ambient conditions, and the selective photoreduction is a very facile process. The results of qua

Twisting mice move the dystonia field forward

A common form of the hyperkinetic movement disorder dystonia is caused by mutations in the gene TOR1A (located within the DYT1 locus), which encodes the ATPase torsinA. The underlying neurobiological mechanisms that result in dystonia are poorly understood, and progress in the field has been hampered by the absence of a dystonia-like phenotype in animal models with genetic modification of Tor1a a.

Trauma and Poor Mental Health in Relation to Economic Status: The Case of Cambodia 35 Years Later.

Cambodia is one of the poorest countries in south-east Asia and is still emerging from the events of the Khmer Rouge reign. It has been suggested that the atrocities experienced by the Cambodian population can explain why Cambodia continues to lag behind its neighbours in economic outcomes. The purpose of this study is to investigate whether there is an association between exposure to past trauma

Demand-Driven Dynamic Spectrum Allocation in Heterogeneous Cellular Networks

In this paper, we address the dynamic spectrum allocation problem in next generation cellular networks under the coordinated dynamic spectrum access (CDSA) model. Firstly, considering spectrum demands of base stations, we formulate spectrum allocation under physical interference models as a nonlinear optimization problem. Then, we propose a demand-driven dynamic spectrum allocation algorithm by tr

Magnetocrystalline anisotropy and uniaxiality of MnAs/GaAs(100) films

We present an investigation of the magnetic behavior of epitaxial MnAs films grown on GaAs(100). We address the dependence of the magnetic moment, ferromagnetic transition temperature (T-c), and magnetocrystalline anisotropy constants on epitaxial conditions. From thorough structural and magnetic investigations, our findings indicate a more complex relationship between strain and magnetic properti

Study of DNA methylation in human pancreatic islets

Popular Abstract in Swedish Diabetes är ett samlingsnamn för sjukdomar som ger förhöjt blodsocker (glukos) som gemensam nämnare. Diabetes ökar stort runt om i världen och ”International Diabetes Federation” (IDF) meddelade att det år 2014 fanns 387 miljoner individer med diabetes globalt och att denna siffra förväntas öka till 592 miljoner individer till år 2035. Ungefär 77% av alla som insjuknar Today type 2 diabetes is a common disease with a worldwide prevalence of 8.3%. The disease is characterised by hyperglycaemia which is a result of insufficient insulin secretion from the beta-cells in the pancreatic islets as well as an insulin resistance seen in the target tissues. Type 2 diabetes is a multifactorial disease with genetic, epigenetic and environmental background. In study I we in

Timing of the deglaciation in southern Patagonia: Testing the applicability of K-Feldspar IRSL

The timing of the ice margin retreat of the Late Glacial Patagonian Ice Sheet (PIS) in southern Patagonia has been the object of discussion for many years. In order to resolve questions about the complex response of the PIS to past climate change, any geological interpretation and data modelling need evaluation against an absolute chronology. The aim of this project is to investigate the applicabi

Surface science of free standing semiconductor nanowires

Due to the wide range of possible applications, there is a strong current interest in semiconductor nanowires, that began around the start of the millennia. As a result, a number of important new surface science challenges of both fundamental and practical nature have emerged. Surfaces govern important processes for nanowire growth, physical properties and the ability of nanowires to interact with

New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG)

Treatment in medical oncology is gradually shifting from the use of nonspecific chemotherapeutic agents toward an era of novel targeted therapy in which drugs and their combinations target specific aspects of the biology of tumor cells. Multiple myeloma (MM) has become one of the best examples in this regard, reflected in the identification of new pathogenic mechanisms, together with the developme

Climate Change : Believing and seeing implies adapting

Knowledge of factors that trigger human response to climate change is crucial for effective climate change policy communication. Climate change has been claimed to have low salience as a risk issue because it cannot be directly experienced. Still, personal factors such as strength of belief in local effects of climate change have been shown to correlate strongly with responses to climate change an

Low concentrations, potential ecological consequences: Synthetic estrogens alter life-history and demographic structures of aquatic invertebrates

Contraceptive drugs are nowadays found in aquatic environments around the globe. Particularly, 17 alpha-ethinylestradiol (EE2) may act even at low concentrations, such as those recorded in natural ecosystems. We evaluated the physiological effects of EE2 on cyclopoids and calanoids, common copepods in both marine and freshwater communities. We used three EE2 concentrations and assessed its impact

Differentiation of human embryonic stem cells into dopaminergic neurons for transplantation in Parkinson's disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder, characterized by tremor, muscle rigidity and bradykinesia, which is primarily due to the degeneration of nigrostriatal dopaminergic neurons. Currently, patients are primarily treated with L-dopa and other drugs that enhance dopaminergic function. Those are effective during the first years, but eventually the majority of patients

Flow-Through-Mediated Surface Immobilization of Sub-Micrometre Particles in Monolithic Cryogels

Particles with functional groups on their surface were immobilized on premade cryogels through covalent bonding to maximize the accessibility of the target molecules to the surface of the particles. The physical properties of the composite cryogel were characterized by SEM, texture analysis and nitrogen adsorption. Different key factors affecting immobilization were also investigated, e.g., recirc

A European Perspective on the Service Delivery Systems for Assistive Technology - Differences and Similarities Between Latvia and Sweden.

National laws and regulations on service delivery systems (SDS) for assistive technology (AT) in Europe aim to support the activity and participation of people with disabilities. The aim of this paper was to study similarities and differences in the SDS for AT of one Eastern and one Western EU member state. The legislation and regulations, and their operationalization were described from the persp

Optimal lag-length choice in stable and unstable VAR models under situations of homoscedasticity and ARCH

The performance of different information criteria - namely Akaike, corrected Akaike (AICC), Schwarz Bayesian (SBC), and Hannan-Quinn - is investigated so as to choose the optimal lag length in stable and unstable vector autoregressive (VAR) models both when autoregressive conditional heteroscedasticity (ARCH) is present and when it is not. The investigation covers both large and small sample sizes