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One of the longest debates in biology has been over the relative importance of different isolating barriers in speciation. However, for most species, there are few data evaluating their relative contributions and we can only speculate on the general roles of pre- and postzygotic isolation. Here, we quantify the absolute and cumulative contribution of 19 potential reproductive barriers between two

The number of applications sharing the same embedded device is increasing dramatically. Very efficient mechanisms (resource managers) for assigning the CPU time to all demanding aplications are needed. Unfortunately existing optimization-based resource managers consume too much resource themselves. In this paper, we address the problem of distributed convergence to efficient CPU allocation for ti

Background: Plasmodium falciparum is the most pathogenic of the human malaria parasite species and a major cause of death in Africa. It's resistance to most of the current drugs accentuates the pressing need for new chemotherapies. Polyamine metabolism of the parasite is distinct from the human pathway making it an attractive target for chemotherapeutic development. Plasmodium falciparum spermidin

Lactobacillus kunkeei is the most abundant bacterial species in the honey crop and food products of honeybees. The 16S rRNA genes of strains isolated from different bee species are nearly identical in sequence and therefore inadequate as markers for studies of co-evolutionary patterns. Here, we have compared the 1.5 Mb genomes of ten L. kunkeei strains isolated from all recognized Apis species and

We report the novel observation that engagement of beta 2 integrins on human neutrophils is accompanied by increased levels of the small GTPases Rap1 and Rap2 in a membrane-enriched fraction and a concomitant decrease of these proteins in a granule-enriched fraction. In parallel, we observed a similar time-dependent decrease of gelatinase B (a marker of specific and gelatinase B-containing granule

The possibility to study variations in the oxygen isotopic ratio with photon tagged nuclear reaction analysis (pNRA) is evaluated in the current work. The experiment described in the article was performed at Lund Ion Beam Analysis Facility (LIBAF) with a 2 MeV deuteron beam. Isotopic fractionation of light elements such as carbon, oxygen and nitrogen is the basis of many analytical tools in hydrol

In this report on 303 gliomas we show the highest frequency of TERT promoter mutations in gliobastomas (80%) followed by oligodendrogliomas (70%) and astrocytomas (39%). We observed positive association between TERT promoter and IDH mutations in oligodendroglial tumors (OR = 26.3; 95% CI 2.5-250.2) and inverse association in primary glioblastomas (OR = 0.13; 95% CI 0.03-0.58). Tumors with TERT pro

We observe that the recent quasi-polynomial time approximation scheme (QPTAS) of Adamaszek and Wiese for the Maximum Weight Independent Set of Polygons problem, where polygons have at most a polylogarithmic number of vertices and nonnegative weights, yields: 1. a QPTAS for the problem of finding, for a set S of n points in the plane, a planar straight-line graph (PSLG) whose vertices are the point

A search for supersymmetry (SUSY) in events with large missing transverse momentum, jets, and at least one hadronically decaying tau lepton, with zero or one additional light lepton (e/mu), has been performed using 4.7 fb(-1) of proton-proton collision data at root s = 7 TeV recorded with the ATLAS detector at the Large Hadron Collider. No excess above the Standard Model background expectation is

Much evidence highlights the importance of polyamines for VSMC (vascular smooth muscle cell) proliferation and migration. Cav-1 (caveolin-1) was recently reported to regulate polyamine uptake in intestinal epithelial cells. The aim of the present study was to assess the importance of Cav-1 for VSMC polyamine uptake and its impact on cell proliferation and migration. Cav-1 KO (knockout) mouse aorti

The regeneration niche has been little investigated in studies of community assembly and plant distribution. We examined adaptive associations between seedling traits and habitat specialization. Two habitat contrasts were investigated across several evolutionary lineages of angiosperms: species specialized to forest vs. open habitats and to dry vs. wet habitats. We also tested whether effects of s

Background and purpose Bone morphogenic proteins (BMPs) can be used in non-unions to replace autograft. BMPs induce osteoblasts and (less well known) also osteoclasts, which can in turn be controlled by a bisphosphonate. In the present study, our aim was to improve the biological effect of autologous bone graft by adding an anabolic BMP, with or without bisphosphonates, in an open-fracture model p

In multiowner wireless networks, access points (APs) are owned and operated by different administrations, leading to significant authentication delays during handoff between APs. We propose to exploit the trust between the owners of neighboring APs for reducing the authentication delay. In the proposed authentication scheme, neighboring APs that trust each other share the security key for the visi

This Letter reports on a first measurement of the inclusive W + jets cross section in proton-proton collisions at a centre-of-mass energy of 7 TeV at the LHC, with the ATLAS detector. Cross sections, in both the electron and muon decay modes of the W-boson, are presented as a function of jet multiplicity and of the transverse momentum of the leading and next-to-leading jets in the event. Measureme

PalCom is a pervasive middleware that enables users to combine services from different devices into assemblies, or usage scenarios. The mechanism of device discovery in PalCom builds an ad-hoc network of interconnected devices while replacing cross-network periodic keep-alive messages with timely forwarded events that notify devices about the discovery and undiscovery of each other. Moreover, the

The factors that determine species' range limits are of central interest to biologists. One particularly interesting group comprises odonates (dragonflies and damselflies), which show large differences in secondary sexual traits and respond quickly to climatic factors, but often have minor interspecific niche differences, challenging models of niche-based species coexistence. We quantified the env

Background: Oral polio vaccine (OPV) is recommended to be given at birth together with BCG vaccine. While we were conducting two trials including low-birth-weight (LBW) and normal-birth-weight (NBW) infants in Guinea-Bissau, OPV was not available during some periods and therefore some infants did not receive OPV at birth, but only BCG. We investigated the effect of OPV given simultaneously with BC

Although recent evidence is somewhat ambiguous, if not confusing, Patrick Grim still seems to believe that his Cantorian argument against omniscience is sound. According to this argument, it follows by Cantor’s power set theorem that there can be no set of all truths. Hence, assuming that omniscience presupposes precisely such a set, there can be no omniscient being. Reconsidering this argument, h