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The Primacy of Right. On the Triad of Liberty, Equality and Virtue in Wollstonecraft's Political Thought

I argue along the following lines: For Wollstonecraft, liberty is independence in two different spheres, one presupposing the other. On the one hand, liberty is independence in relation to others, in the sense of not being vulnerable to their whim or arbitrary will. Call this social, or political, liberty. For liberty understood in this way, infringements do not require individual instances of int

Long-term follow-up and cost analysis following surgery for small bowel obstruction caused by intra-abdominal adhesions.

Background: This study examined the natural course of patients following surgery for small bowel obstruction (SBO) caused by abdominal adhesions. In addition, a cost analysis was performed. Methods: A retrospective analysis was undertaken of 102 patients who underwent surgery between 1987 and 1992 for intestinal obstruction due to abdominal adhesions. Results: Median follow-up was 14 years. The 10

Understanding the unperceivable: ideas about cholesterol expressed by middle-aged men with recently discovered hypercholesterolaemia

OBJECTIVE: We aimed to describe the perception of hypercholesterolaemia among middle-aged, urban men who had recently received the diagnosis of moderate hypercholesterolaemia. METHOD: Within a project screening for risk factors for coronary heart disease among 453 men, 63 were identified as moderately hypercholesterolaemic. Among these, 62 agreed to tape-recording and transcription of the first co

Murine models of acute neuronopathic Gaucher disease

Gaucher disease (GD) is an autosomal recessive lysosomal storage disorder caused by mutations in the glucosidase, beta, acid (GBA) gene that encodes the lysosomal enzyme glucosylceramidase (GCase). GCase deficiency leads to characteristic visceral pathology and, in some patients, lethal neurological manifestations. Here, we report the generation of mouse models with the severe neuronopathic form o

Mediterranean dietary pattern and prediction of all-cause mortality in a US population - Results from the NIH-AARP diet and health study

Background: The Mediterranean diet has been suggested to play a beneficial role for health and longevity. However, to our knowledge, no prospective US study has investigated the Mediterranean dietary pattern in relation to mortality. Methods: Study participants included 214 284 men and 166 012 women in the National Institutes of Health (NIH)-AARP ( formerly known as the American Association of Ret

Modeling transmission and scatter for photon beam attenuators

The development of treatment planning methods in radiation therapy requires dose calculation methods that are both accurate and general enough to provide a dose per unit monitor setting for a broad variety of fields and beam modifiers. The purpose of this work was to develop models for calculation of scatter and transmission for photon beam attenuators such as compensating filters, wedges, and blo

Modelling of hydrogen cyanide formation in room fires

A chemical kinetics model for calculation of the formation of hydrogen cyanide (HCN) has been made. The combustion of a mixture of methylamine and ethylene has been modelled using the stationary laminar flamelet concept. The flamelet calculations are based on several thousand elementary reaction steps including the chemical kinetics of HCN in combustion. The flamelets for both cold (293 K) and hot

Comparison of two leukapheresis programs for computerized collection of blood progenitor cells on a new cell separator

BACKGROUND: Peripheral blood progenitor cells (PBPCs) can be collected on various cell separators. Two leukapheresis programs (LP-MNC and LP-PBSC-Lym) were evaluated for computerized collection of PBPCs on a new cell separator. STUDY DESIGN AND METHODS: Leukapheresis assisted by the LP-MNC or LP-PBSC-Lym software was performed for the harvesting of PBPCs in 52 oncology patients after chemotherapy

Frost Resistance of Building Materials : Proceedings of the 3rd Nordic Research Seminar in Lund, 1999

This report contains papers presented at a Research Seminar , or rather "workshop", organised by our Department. It is the third in a series. The previous seminars were held in 1993 and 19961• The seminar is "Nordic", by which is meant that the speakers came from the Scandinavian countries -Demnark, Norway, Sweden- and Finland. Certainly there are other Nordic countries in which frost is a real pr

Conservation laws of the Camassa-Holm equation

We use the bi-Hamiltonian structure of the Camassa-Holm equation to show that its conservation laws H-n[m] are homogeneous with respect to the scaling m --> lambdam. Moreover, a direct argument is presented proving that H-1, H-2,..., are of local character. Finally, simple representations of the conservation laws in terms of their variational derivatives are derived and used to obtain a constructi

Expression of antioxidant enzymes in rat retinal ischemia followed by reperfusion.

To evaluate the expression and protein levels of antioxidant enzymes in the rat retina exposed to oxidative stress induced by ischemia-reperfusion injury. Retinal ischemia was induced in female Wistar rats by ligation of the optic nerve and vessels behind the left eye bulb, and was followed by reperfusion for 0, 3, 6, or 24 hours. The right eye served as control. RNA and protein were extracted sim

Efficient internalization into low-passage glioma cell lines using adenoviruses other than type 5: an approach for improvement of gene delivery to brain tumours

There is a need for improvement of the commonly used adenovirus vectors based on serotype 5. This study was performed on three adenovirus serotypes with a CAR-binding motif (Ad4p, Ad5p and Ad17p) and three non-CAR-binding serotypes (Ad11p, Ad16p and Ad21p). The capacity of these alternative adenovirus vector candidates to deliver DNA into low-passage glioma cell lines from seven different donors w

Beach nourishment projects, practices, and objectives - a European overview

The uses of beach fill in the countries of the European Union are highlighted and discussed with respect to the general situation, project type and objectives, design and evaluation procedures, legal framework, and financial aspects. As expected, significant differences were found among the investigated countries. In general, the study shows that it would be very profitable for south European coun