BACKGROUND: The progression of tumor growth requires the recruitment of new blood vessels. It has been suggested that the degree of neovascularization would correlate with clinical prognosis. The purpose of the present study was to ascertain whether tumor vascularization correlated with clinical outcome in cases of primary squamous cell carcinoma of the head and neck (SCCHN).METHODS: In tumor biop

The present invention relates to a method of extg. 3-​hydroxypropionaldehyde (3-​HPA) and​/or derivs. thereof from an aq. soln. comprising 3-​HPA. This method comprises (a) contacting the aq. soln. comprising 3-​HPA with chitosan and​/or chitosan comprising polymers, (b) sepg. the 3-​HPA bound chitosan and​/or chitosan comprising polymers, and (c) washing the 3-​HPA bound chitosan and​/or chitosan

We analyze the role of migrants in productivity growth in the three largest European countries—France, Germany and the United Kingdom—in the years 1994–2007, using Total Factor Productivity. Unlike previous research, which mainly employs a regional approach, our analysis is at the sectoral level: this allows to distinguish the real contribution of migrants to productivity from possible inter-secto

For a better understanding of possible physical links between geophysical observables and earthquake characteristics, it is important to analyze statistical spatiotemporal patterns in nature related to such events. For this purpose, characteristic changes in groundwater level (GWL) were observed before and after the 2016 Kumamoto earthquake in Japan. Previous research has shown that self-organizin

AIM: The aim of this study was to assess the predictive role of biomarkers, associated with cardiovascular stress and its neuroendocrine response as well as renal function, in relation to mortality and risk of re-hospitalization among consecutive patients admitted because of heart failure (HF).METHODS AND RESULTS: A total of 286 patients (mean age, 75 years; 29% women) hospitalized for newly diagn

Background: Plasmodium falciparum malaria is an important cause of morbidity in northern Uganda. This study was undertaken to assess village-, household-, and individual-level risk factors of asymptomatic falciparum malaria in children in 12 villages in northern Uganda. Methods: Between 10/2011 and 02/2014, 1006 apparently healthy children under 16 years old were enrolled in 12 villages using a st

To identify homeless people with chronic kidney disease (CKD) who were at highest risk for end-stage renal disease (ESRD), we studied 982 homeless and 15,674 domiciled people with CKD receiving public health care. We developed four risk prediction models for the primary outcome of ESRD. Overall, 71 homeless and 888 domiciled people progressed to ESRD during follow-up (median: 6.6 years). Homeless

Background Cardiac fibrosis is thought to play a central role in the pathogenesis of atrial fibrillation (AF). Retrospective studies have suggested that circulating fibrosis biomarkers are associated with AF, but prospective studies are limited. Methods We measured circulating levels of 2 fibrosis biomarkers, procollagen type III, N-terminal propeptide (PIIINP) and transforming growth factor β1 am

Systematic profiling of expressed gene products represents a promising research strategy for elucidating the molecular phenotypes of islet cells. To this end, we have combined complementary genomic and proteomic methods to better assess the molecular composition of murine pancreatic islet glucagon-producing αTC-1 cells as a model system, with the expectation of bypassing limitations inherent to ei

Background: Membrane proteins constitute up to 30% of the human proteome. These proteins have special properties because the transmembrane segments are embedded into lipid bilayer while extramembranous parts are in different environments. Membrane proteins have several functions and are involved in numerous diseases. A large number of prediction methods have been introduced to predict protein subc

Aims. The central region of a circumstellar disk is difficult to resolve in global numerical simulations of collapsing cloud cores, but its effect on the evolution of the entire disk can be significant. Methods. We used numerical hydrodynamics simulations to model the long-term evolution of self-gravitating and viscous circumstellar disks in the thin-disk limit. Simulations start from the gravitat

Assessment of bilingual children in only one language fails to acknowledge their distributed linguistic competence and has been shown to overidentify language disorder in bilingual populations. However, other factors, sometimes associated with bilingualism, may also contribute to low results in language assessments. Our aim was to examine the impact of these factors on language abilities. We used

Bakgrund Med en snabbt växande äldre populationsgrupp kommer även andelen med kognitiva störningar, som demens, att växa. Det är således nödvändigt med forskning på kognition och åldrande. Denna avhandling, genom fyra delarbeten, redogör för testledareffekter vid kognitionsmätningar och hur yngre födelsekohorter (generationer) presterar bättre än äldre på kognitionstester. Den kommer även förklaraGiven a growing population of older adults and the common occurrence of natural as well as pathological cognitive decline, i.e. dementia, there is a need to better understand how to accurately measure and classify level of cognitive functioning. Both using multiple test administrators to collect cognitive data and what year the participant is born (birth cohort effects) can influence participants’

Abstract: Catalysts used for selective catalytic reduction of NOx on diesel engines were deactivated for 890 and 2299 h in the exhausts from a diesel engine running on Swedish diesel fuel mark 1. The deactivated catalytic monoliths (100 mm long) were cut in 10 mm pieces along their axis and were characterized by physicochemical methods as well as by determination of the activity in the reduction o

Background Nocturia is one of the most prevalent and bothersome lower urinary tract symptoms (LUTS) in men, leading to increased morbidity and mortality and a considerable economic burden on healthcare systems. Understanding its natural history, effect of pharmacotherapy, and predictors of failure of pharmacotherapy would allow optimised patient management. Objective To evaluate the prevalence an

Equatorial volcanic eruptions are known to impact the atmospheric circulation on seasonal time scales through a strengthening of the stratospheric zonal winds followed by dynamic ocean-atmosphere coupling. This emerges as the positive phase of the North Atlantic Oscillation in the first 5 years after an eruption. In the North Atlantic, other modes of atmospheric circulation contribute to the clima

In this paper, we study how increasing the cognitive demands of multitasking affects time preferences. The novelty of this paper is that it studied how time perception mediates the effect of multitasking on time preferences. Results from experimental psychology have demonstrated that people tend to experience the passage of time as quicker when they are busy with cognitively-demanding tasks. If ti

OBJECTIVES: There is highly suggestive evidence for an effect of air pollution exposure on dementia-related outcomes, but evidence is not yet present to clearly pinpoint which pollutants are the probable causal agents. The aims of this study was to assess the longitudinal association between exposures of fine ambient particulate matter (PM2.5) from residential wood burning, and vehicle exhaust, wi