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Effect of sodium taurodeoxycholate on PEO-PPO-PEO triblock copolymer F127 with incorporated SNAP: Insights into micellization, gelation, and nitric oxide release

We report the first incorporation of S-nitroso-N-acetylpenicillamine (SNAP) into micellar systems of the poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) triblock copolymer Pluronic® F127 for nitric oxide (NO) delivery and show how sodium taurodeoxycholate (NaTDC) modulates F127 micellization and gelation. Using differential scanning calorimetry, small-angle X-ray scat

Distal Radius Fractures in the Elderly

This thesis combines quantitative, qualitative, and experimental approaches to address different aspects of distal radius fractures (DRFs) in the elderly.Study I was a registry-based cohort study of 5,536 DRF patients, of whom 259 (5%) sustained a concomitant distal metaphyseal ulna fracture. These patients, with a mean age of 73 years (SD 15), had nearly twice the odds of reporting severe symptom

Index Theorems with Spectral Localizers

The Atiyah--Singer index theorem is a foundational result in mathematics, providing a deep connection between the analytical properties of an elliptic differential operator and the topological properties of its underlying manifold. This thesis focuses on a numerical approach to index theory for generalized Toeplitz operators. Building on the work of Loring and Schulz-Baldes, we utilize the spectra

A Sea of Plasticity

An exploration of perspectives in art through technology, by way of Graham Harman

Trichotillomania and Risk of Alcohol- and Drug-Related Problems

Background: Trichotillomania is an understudied psychiatric disorder characterized by repeated hair-pulling resulting in hair loss. Little is known about the risk of problematic substance use in this patient group. In this nationwide matched cohort study, we investigated the association between trichotillomania and substance-related problems. Methods: We linked various nationwide administrative an