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Bakgrund: Beslut om livsuppehållande åtgärder (LUÅ) inom akutsjukvård utgör en komplex del av sjuksköterskans yrkesutövning och innebär ofta etiska och emotionella utmaningar. Utförandet av livsuppehållande åtgärder kan medföra att förlängt liv, ibland på bekostnad av en försämrad livskvalitet för patienten. Den akuta och tidskritiska vårdmiljön medför risk för att patientens autonomi, delaktighetBackground: Decisions regarding life-sustaining treatment (LUÅ) in emergency care represent a complex aspect of nursing practice and often involve ethical and emotional challenges. The implementation of life-sustaining treatment can prolong life, sometimes at the expense of the patient’s quality of afterlife. The acute and time-critical care environment entails a risk that the patient’s autonomy,

Bakgrund: Akutsjukvården präglas av hög arbetsbelastning, tidsbrist och begränsade resurser, vilket skapade en spänd arbetsmiljö för sjuksköterskor. Krav-Kontroll-stödmodellen beskriver hur kombinationen av arbetskrav, kontroll och socialt stöd påverkar balans eller obalans, medan coping och resiliens är återhämtningsförmågor som påverkar sjuksköterskan att hantera påfrestningar. Syfte: SjuksköteBackground: Emergency care is characterized by high workload, time constraints, and limited resources, which create a tense work environment for nurses. The Job Demand–Control–Support model describes how the combination of job demands, control, and social support affects balance or imbalance, while coping and resilience are recovery abilities that influence the nurse’s capacity to handle stressors

Över hela världen ingick sjuksköterskor i en första linjen-strid mot viruset SARS CoV-2 som ledde till att COVID-19-pandemin förklarades i mars 2020 (WHO, 2020). Akutmottagningen fungerar som en första instans för de flesta patienter som passerar in till sjukhus vid akut sjukdom vilket ledde till att stora förändringar behövde genomföras på kort tid i form av utökade isoleringsplatser, organise

Bakgrund: Akutmottagningar i Sverige och internationellt står inför utmaningar med ökade patientflöden, överbelastning och långa väntetider. Teamtriage, där olika professioner arbetar och bedömer patienten tillsammans vid ankomst, har utvecklats som en möjlig lösning för att effektivisera vårdflödet. Syfte: Syftet med litteraturstudien var att beskriva teamtriagens effekter på vårdflöde, patientsä

Introduction: Despite factor (F)VIII prophylaxis, a perceived increased risk of bleeding for some people with severe haemophilia A (PwSHA) exists, limiting physical activity (PA) and restricting quality of life (QoL). Aim: HemiNorth 2 (EudraCT# 2020-003256-32) is an interventional study evaluating the impact of switching from FVIII prophylaxis to emicizumab in PwSHA without FVIII inhibitors who ha

Recent technological developments in warehousing have introduced new risks. This paper presents an integrative review that combines insights from highly automated warehouse systems (HAWS) and risk management, providing a comprehensive understanding of technology-related warehouse disruptions and vulnerabilities. We identify five major disruptions that can affect HAWS: cyberattacks, technology sabo

Biases in animal behaviour research are inevitable consequences of our societal and cultural standpoint. To remove our biases, the first stage is to identify them. We call on individual researchers to adopt a more active approach to addressing bias within their research. We propose that biases exist within a matrix defined by the general acceptance of a bias's existence and the understanding of th

Education reduces the intergenerational transfer of poverty and boosts growth according to the Social Investment (SI) approach (Morel, Palier, and Palme 2011). However, educational systems differ in their capacity to promote equality and produce the skills needed in today‘s knowledge economies. Despite extensive scholarship on how education policies vary in terms of their social and economic effec

Massive multiple input, multiple output (MIMO) systems are crucial for enhancing spectral efficiency and link reliability in next-generation wireless communications. However, high Peak-to-Average Power Ratio (PAPR) remains a significant challenge, leading to power inefficiencies and signal distortion. This paper presents a low complexity method for PAPR reduction using hard clipping tailored for f

Background: Infections trigger complex immune responses, with conserved as well as disease-specific characteristics. Methods: Proteomic screening technology and gene expression analysis were used here to define the immune response in infants, with their first episode of febrile urinary tract infection. Urine and peripheral blood samples were obtained at enrollment and at follow-up, after 6 months.

This study examines the current e-learning implementation in Tanzanian universities, highlighting the challenges and opportunities associated with its utilisation. Data was collected from 610 respondents, including e-learning support staff, lecturers, and students from five selected universities through questionnaires and interviews. The findings reveal that universities in Tanzania still face imp

Background: The Earth Hologenome Initiative (EHI) is a global endeavor dedicated to revisit fundamental ecological and evolutionary questions from the systemic host–microbiota perspective, through the standardized generation and analysis of joint animal genomic and associated microbial metagenomic data. Results: The first data release of the EHI contains 968 shotgun DNA sequencing read files conta

Purpose: Cardiorespiratory fitness (CRF) and muscle strength are associated with cancer risk/mortality in adults. However, there is yet no evidence for pediatric tumors. This study investigated the association of CRF and muscle strength with several tumor-related phenotypes in an aggressive childhood malignancy, high-risk neuroblastoma (HR-NB). Methods: Twelve mice bearing orthotopic HR-NB were st

Background: The cold-shock domain protein YB-1 is overexpressed in pleural mesothelioma (PM) and was shown to contribute to increased cell migration and platinum resistance. Methods: Phosphorylation of YB-1 at position serine 102 was analysed by immunohistochemistry, immunofluorescence and immunoblotting in PM tissue specimens and cell lines. Intracellular localisation experiments involved immunob

Background: The increased risk of colorectal cancer (CRC) associated with family history of both colorectal in situ or invasive carcinomas (Stage 0 to IV) and colorectal polyps is attributed solely to family history of CRC, resulting in an underestimation of the actual risk. We aimed to assess the association between overall and early-onset CRC (EOCRC) risk and family history of both colorectal ca

The dystrophin-glycoprotein complex (DGC) is composed of peripheral and integral membrane proteins at the muscle cell membrane that link the extracellular matrix with the intracellular cytoskeleton. While it is well established that genetic mutations that disrupt the structural integrity of the DGC result in numerous muscular dystrophies, the 3D structure of the complex has remained elusive. Two r

As the total cost of renewable electricity falls lower than the price of fossil fuel, not only can electricity be used to replace fossil fuels using batteries in vehicles but it can also be used to produce fuels. This makes it possible to replace fuels in sectors not easily directly electrified. It also provides new ways of balancing the electricity system. When renewable electricity is cheap a lo

This chapter critically examines a number of ethical dilemmas at stake for professionals working with refugee children and families in Denmark within the field of early childhood education. While national guidelines promote diversity by framing cultural differences as valuable resources, integration policies often result in efforts aimed at assimilation. The chapter explores how everyday ethical j

This article examines, firstly, how legal and safe pathways, in particular resettlement and humanitarian corridors, are regulated in French legislation and how they are implemented in practice, and secondly, the implications of this regulation and implementation for the promise of legal pathways to offer regular entry for asylum purposes. Using a legal and policy approach, our research shows that